1-(p-methoxyphenyl)-1-(thiophene-2-yl)-prop-2-yn-1-ol | 211796-85-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-(p-methoxyphenyl)-1-(thiophene-2-yl)-prop-2-yn-1-ol
• 英文别名: 1-(4-methoxyphenyl)-1-(2-thienyl)-2-propyn-1-ol；1-(thiophen-2-yl)-1-(4-methoxyphenyl)-prop-2-yn-1-ol；1-(4-methoxyphenyl)-1-(2-thienyl)-prop-2-yn-1-ol；1-(4-methoxyphenyl)-1-(thiophene-2-yl)prop-2-yn-1-ol；1-(4-methoxyphenyl)-1-thiophen-2-ylprop-2-yn-1-ol
• CAS: 211796-85-9
• 化学式: C₁₄H₁₂O₂S
• 分子量: 244.314
• InChiKey: KLTRLSNGWVFQNG-UHFFFAOYSA-N

物化性质

• 沸点：
  379.0±42.0 °C(Predicted)
• 密度：
  1.237±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  57.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-(p-methoxyphenyl)-1-(thiophene-2-yl)-prop-2-yn-1-ol 在 对甲苯磺酸 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 反应 48.0h， 生成
  参考文献：
  名称：

  光调制材料的前体噻吩取代的3 H-萘[2,1 - b ]吡喃的合成

  摘要：

  3的合成ħ -萘并[2,1- b ]吡喃9 - 21连接于噻吩部分进行说明。两种不同的合成方法被用于制备这些新颖的功能化化合物，并报道了它们在溶液中的光谱动力学性质。

  DOI：

  10.1002/hlca.19980810540
• 作为产物：
  描述：

  2-(4-甲氧基苄氧基)噻吩 、 乙炔钠 以 xylene 为溶剂， 反应 48.0h， 以90%的产率得到1-(p-methoxyphenyl)-1-(thiophene-2-yl)-prop-2-yn-1-ol
  参考文献：
  名称：

  光调制材料的前体噻吩取代的3 H-萘[2,1 - b ]吡喃的合成

  摘要：

  3的合成ħ -萘并[2,1- b ]吡喃9 - 21连接于噻吩部分进行说明。两种不同的合成方法被用于制备这些新颖的功能化化合物，并报道了它们在溶液中的光谱动力学性质。

  DOI：

  10.1002/hlca.19980810540

文献信息

• Oligothiophene-Linked Bisnaphthopyrans: Sequential and Temperature-Dependent Photochromism
  作者：Weili Zhao、Erick M. Carreira

  DOI：10.1002/chem.200600958

  日期：2007.3.16

  Photochromic bisnaphthopyrans linked with oligothiophenes were synthesized and their photochromic behavior studied. Sequential and temperature-dependent photochromism was observed in the oligothiophene linked bisnaphthopyrans. The kinetics of photo and thermal processes in bisnaphthopyrans in comparison with naphthopyrans were studied. Substituent and linking effects on the photochromic properties

  合成了与寡噻吩连接的光致变色双萘并吡喃并研究了它们的光致变色行为。在寡噻吩连接的双萘并吡喃中观察到顺序和温度相关的光致变色现象。研究了萘并吡喃与萘并吡喃的光和热过程动力学。讨论了取代基和连接效应对光致变色性质的影响。我们证明了两个光致发色团之间的串扰取决于寡噻吩接头的长度。联噻吩接头的存在导致了高着色性和着色的高量子产率。
• Facile One-Pot Synthesis of Photochromic Pyrans
  作者：Weili Zhao、Erick M. Carreira

  DOI：10.1021/ol035599x

  日期：2003.10.1

  [reaction: see text]. Photochromic pyrans, including [3H]naphtho[2,1-b]pyrans, [2H]naphtho[1,2-b]pyrans, indeno-fused naphtho[1,2-b]pyrans, and heteroannulated pyrans, were synthesized in excellent yields through a facile one-pot procedure by reaction of propargyl alcohol and naphthol or phenol derivatives in the presence of 5 mol % PPTS and 2 equiv of (MeO)3CH. Symmetrical and nonsymmetrical bispyrans

  [反应：请参见文字]。合成了包括[3H]萘[2,1-b]吡喃，[2H]萘[1,2-b]吡喃，茚并稠合的萘[1,2-b]吡喃和异环吡喃的光致变色吡喃。在5 mol％PPTS和2当量（MeO）3CH存在下，通过炔丙醇与萘酚或苯酚衍生物反应，通过简便的一锅法获得优异的收率。对称和非对称双吡喃也可以使用该方案制备。
• Two Stage Colour Modulation of Triarylmethine Dyes Derived from a Photochromic Naphthopyran
  作者：Christopher D. Gabbutt、B. Mark Heron、Suresh B. Kolla、Matthew Mcgivern

  DOI：10.1002/ejoc.200800178

  日期：2008.4

  The synthesis of the unsymmetrical triarylmethine dyes 4derived from a lithiated naphthopyran and diaryl ketones is reported. In toluene solution 4 display a typical reversible photochromic response becoming coloured upon irradiation with UV light and fading upon cessation of irradiation. At low pH an intensely coloured dye cation is generated and UV irradiation of this solution results in a further

  报道了由锂化萘并吡喃和二芳基酮衍生的不对称三芳基次甲基染料 4 的合成。在甲苯溶液 4 中，显示出典型的可逆光致变色响应，在用紫外线照射时变得有色，并在停止照射时褪色。在低 pH 值下，会产生强烈着色的染料阳离子，并且由于萘并吡喃单元的光致变色循环，该溶液的紫外线照射会导致进一步的颜色变化
• Photochromic bis-naphthopyran compounds and methods for their manufacture
  申请人：——

  公开号：US20030078441A1

  公开（公告）日：2003-04-24

  The invention provides photochromic bis-naphthopyran compounds as well as methods for their manufacture and their use. The bis-naphthopyran compounds of the invention exhibit a wide range of color, i.e., from pink to purple to blue gray, upon activation by a source of UV light. Additionally, the bis-naphthopyran compounds of the present invention exhibit broad coloration ability, fast response as to both color change on activation and return to original color, and good fatigue-resistance.

  该发明提供了光致变色的双萘吡喃化合物及其制备和使用方法。该发明的双萘吡喃化合物在受到紫外光源激活时，表现出从粉色到紫色到蓝灰色的广泛颜色范围。此外，本发明的双萘吡喃化合物表现出广泛的着色能力，对激活后的颜色变化和恢复到原始颜色的反应速度快，并且具有良好的耐疲劳性。
• Photochromic systems with photoinduced emission modulation of colloidal CdSe quantum wells
  作者：Valery A. Barachevsky、Olga V. Venidiktova、Tatyana M. Valova、Alexander M. Gorelik、Roman B. Vasiliev、Artur A. Khuzin、Airat R. Tuktarov、Pavel V. Karpach、Vitali I. Stsiapura、Gennady T. Vasilyuk、S. A. Maskevich

  DOI：10.1039/c9pp00341j

  日期：2019.11

  A spectroscopic study of photochromic systems containing two-dimensional CdSe nanoparticles (colloidal quantum wells) and photochromic compounds of the thermally relaxing chromene and thermally irreversible diarylethene classes in solutions was carried out. First, the systems were found to exhibit modulation of emission of two-dimensional nanoparticles in accordance with the photochromic transformations of compounds due to Forster resonance energy transfer (FRET) from the two-dimensional nanoparticles to photoinduced photochromic isomers.