[(tri-n-butyl-phosphane)CuCl] | 51430-34-3

• 分子结构分类: 有机化合物 - 有机磷化合物 - 有机膦及其衍生物
• 英文名称: [(tri-n-butyl-phosphane)CuCl]
• 英文别名: Chlorocopper;tributylphosphane；chlorocopper;tributylphosphane
• CAS: 51430-34-3
• 化学式: C₁₂H₂₇ClCuP
• 分子量: 301.319
• InChiKey: QACGFSNEATYORN-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.87
• 重原子数：
  15
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  [(tri-n-butyl-phosphane)CuCl] 、 potassium trifluoroacetate 以 乙醚 为溶剂， 以83%的产率得到[(tri-n-butyl-phosphane)CuO2CCF3]
  参考文献：
  名称：

  [(nBu3P)mCuO2CR] (m = 1, 2, 3) 型的铜 (I) 羧酸盐 - 合成、性质及其作为 CVD 前体的用途

  摘要：

  [(nBu3P)mCuO2CR] 型的铜 (I) 羧酸盐 (m = 1: 3a, R = Me; 3b, R = CF3; 3c, R = Ph; 3d, R = CH=CHPh. m = 2: 4a, R = Me; 4b, R = CF3; 4c, R = Ph; 4d, R = CH=CHPh.m = 3: 8a, R = Me; 8b, R = CF3; 8c, R = CH2Ph; 8d, R = (CH2OCH2)3H; 8e, R = cC4H7O) 可通过以下合成方法获得：[CuO2CR] (1a, R = Me; 1b, R = CF3; 1c, R = Ph; 1d, R = CH=CHPh ) 用 m 等量的 nBu3P (2) (m = 1, 2, 3)，或用 [KO2CCF3] (6) 处理 [(nBu3P)mCuCl] (5a, m = 1; 5b, m = 2)。8a

  DOI：

  10.1002/zaac.200800189
• 作为产物：
  描述：

  三丁基膦 、 以 not given 为溶剂， 生成 [(tri-n-butyl-phosphane)CuCl] 、
  参考文献：
  名称：

  Hessler, Gisbert; Knueppel, Peter C.; Stelzer, Othmar, Chemische Berichte, 1990, vol. 123, p. 653 - 660

  摘要：

  DOI：

文献信息

• 16 alpha-methyl steroids and their preparation
  申请人：THE UPJOHN COMPANY

  公开号：EP0165037A2

  公开（公告）日：1985-12-18

  16-Unsaturated corticoids are readily transformed to correspoding 16α-methyl-17α-hydroxycorticoids, respectively via novel silyl derivatives which are Δ17(20)-steroids, 17α, 20-epoxide steroids and 17α-sityl ether steroids. The first step in the overall process involves the use of a methylating agent, in the presence of a copper catalyst, and then a silylating agent. The last step in the overall process can be carried out under mild conditions, using a peracid.

  16- 不饱和皮质类固醇很容易通过新型硅烷衍生物分别转化为相应的 16α-甲基-17α-羟基皮质类固醇，这些新型硅烷衍生物是 Δ17(20)- 类固醇、17α，20-环氧类固醇和 17α - 叔位醚类固醇。 整个过程的第一步涉及在铜催化剂存在下使用甲基化剂，然后使用硅烷化剂。 整个过程的最后一步可在温和条件下使用过酸进行。
• 9,11-Epoxy-21-hydroxypregnane derivatives
  申请人：THE UPJOHN COMPANY

  公开号：EP0278319A1

  公开（公告）日：1988-08-17

  The compounds 9β,11β-­epoxy-21-hydroxypregna-4,16-diene-3,20-dione 21-acetate and 9β,11β-epoxy-21-hydroxypregna-1,4,16-triene-3,20-­dione 21-acetate.

  9β,11β-环氧-21-羟基孕甾-4,16-二烯-3,20-二酮 21-乙酸酯和 9β,11β-环氧-21-羟基孕甾-1,4,16-三烯-3,20-二酮 21-乙酸酯。
• Shin, H.-K.; Hampden-Smith, M. J.; Duesler, E. N., Canadian Journal of Chemistry, 1992, vol. 70, # 12, p. 2954 - 2966
  作者：Shin, H.-K.、Hampden-Smith, M. J.、Duesler, E. N.、Kodas, T. T.

  DOI：——

  日期：——
• Dithiocarbamate copper(I) and silver(I) complexes: Synthesis, structure and thermal behavior
  作者：Robert Mothes、Holm Petzold、Alexander Jakob、Tobias Rüffer、Heinrich Lang

  DOI：10.1016/j.ica.2015.02.008

  日期：2015.4

  Complexes [M(PBu3)(n)(S2CNRR')] (M = Cu, Ag; n = 1, 2, 3; R = R' = CH2CH@CH2, (CH2)(4), C2H4OH; R = Me, R' = C2H4OH; R = Bu, R' = C2H4OH) (4-9) are accessible by the reaction of [Cu(PBu3)(n)Cl] (1a-c) or [Ag(PBu3)(n)(NO3)] (2a-c) with [K(S2CNRR')] (3a-e). The respective silver(I) dithiocarbamates 7-9 and [Ag(PPh3)(2)(S2CNRR')] (12a, R = Me; 12b, R = Bu) could be synthesized by the subsequent treatment of 3 with [AgNO3] (10) giving [AgS2CNRR'] (11) followed by addition of n equivalents of the phosphine L (L = PBu3, PPh3). Exemplary, the P-31H-1} NMR spectra of [Ag(PBu3)(n)(S2CNMe(C2H4OH)] (n = 1.0, 1.5, 2.0, 2.5, 3.0, 3.5, 4.0, 4.5) were investigated in the temperature range of 308-178 K showing phosphine ligand exchange processes in solution. The molecular structures of 12a, b in the solid state are reported confirming the monomeric architecture with coordination number 4 at silver, which is setup by a chelate-bonded (kappa(2)-S,S') S2CNR(C2H4OH) unit and two coordinated PPh3 ligands. The thermal behavior of selected samples was studied by thermogravimetry. Depending on R, R' and the number of phosphines n, decomposition occurs in varying temperature ranges giving different decomposition residues (CuxS,x = 1.96, 2; Ag, Ag2S), which were characterized by XRPD. (C) 2015 Elsevier B.V. All rights reserved.
• 16$g(a)-METHYLATION PROCESS
  申请人：THE UPJOHN COMPANY

  公开号：EP0308412B1

  公开（公告）日：1992-03-18