2-(7-Chloro-4-hydroxy-1-methylisoquinoline-3-carboxamido)acetic acid | 916171-78-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-(7-Chloro-4-hydroxy-1-methylisoquinoline-3-carboxamido)acetic acid
• 英文别名: 2-[(7-chloro-4-hydroxy-1-methylisoquinoline-3-carbonyl)amino]acetic acid
• CAS: 916171-78-3
• 化学式: C₁₃H₁₁ClN₂O₄
• 分子量: 294.69
• InChiKey: GJXSIWAHDZXUNY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  99.5
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• IMPROVED TREATMENT FOR ANEMIA USING A HIF-ALPHA STABILISING AGENT
  申请人：FIBROGEN, INC.

  公开号：EP1893186A2

  公开（公告）日：2008-03-05
• METHODS FOR INCREASING WHITE BLOOD CELLS
  申请人：Fibrogen, Inc.

  公开号：EP2231156A1

  公开（公告）日：2010-09-29
• Treatment method for anemia
  申请人：Klaus J. Stephen

  公开号：US20060276477A1

  公开（公告）日：2006-12-07

  The present invention relates to improved methods for treating anemia. Methods and compounds useful for treating anemia, wherein the anemia treatment is associated with a lower risk of thrombosis or hypertension compared to that observed with rhEPO therapy, are provided.
• INFLAMMATORY BOWEL DISEASE THERAPIES
  申请人：Colgan Sean P.

  公开号：US20110065771A1

  公开（公告）日：2011-03-17

  The invention relates to methods of treating inflammatory bowel disease in a subject. Methods of promoting intestinal barrier function as well as related compositions are also provided.
• US8962530B2
  申请人：——

  公开号：US8962530B2

  公开（公告）日：2015-02-24