4-dodecylmercapto-butyric acid | 40520-14-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-dodecylmercapto-butyric acid
• 英文别名: 4-Dodecylmercapto-buttersaeure；4-(dodecylthio)butanoic Acid；4-(Dodecylsulfanyl)butanoic acid；4-dodecylsulfanylbutanoic acid
• CAS: 40520-14-7
• 化学式: C₁₆H₃₂O₂S
• mdl: MFCD00088084
• 分子量: 288.495
• InChiKey: HRDGPYWHDRZWEK-UHFFFAOYSA-N

物化性质

• 熔点：
  57.5-58.5 °C
• 沸点：
  419.0±28.0 °C(Predicted)
• 密度：
  0.957±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  19
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.937
• 拓扑面积：
  62.6
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2930909090

反应信息

• 作为反应物：
  描述：

  4-dodecylmercapto-butyric acid 在 双氧水 、 溶剂黄146 作用下， 生成 4-dodecyl sulfonyl butanoic acid
  参考文献：
  名称：

  Some Alkyl and Heterocyclic Sulfides and Sulfones

  摘要：

  DOI：

  10.1021/ja01137a506
• 作为产物：
  描述：

  sodium dodecanethiolate 在 乙醚 、 乙醇 、 lithium 作用下， 生成 4-dodecylmercapto-butyric acid
  参考文献：
  名称：

  Some Alkyl and Heterocyclic Sulfides and Sulfones

  摘要：

  DOI：

  10.1021/ja01137a506

文献信息

• Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof
  申请人：Darteil Raphael

  公开号：US20060154984A1

  公开（公告）日：2006-07-13

  The invention relates to the use of acyl glycerols and the nitrogen- and sulfur-containing analogues thereof in the therapeutic field, particularly in human health. The inventive compounds have advantageous pharmacological properties and are particularly of use for the prevention or treatment of neurodegenerative diseases.

  这项发明涉及在治疗领域中使用酰基甘油及其氮和硫含量类似物，特别是在人类健康领域。这些创新化合物具有有益的药理特性，特别适用于预防或治疗神经退行性疾病。
• Therapeutic use of of acyglycerols and the nitrogen-and sulphur-containing analogues thereof
  申请人：Darteil Raphael

  公开号：US20060252827A1

  公开（公告）日：2006-11-09

  The invention relates to the use of acylglycerols and the nitrogen- and sulfur-containing analogues thereof in therapy, particularly for the treatment of cerebral ischemia. The invention further relates to methods for preparing said derivatives, novel compounds, in particular acylglycerols, the nitrogen- and sulfur-containing analogues thereof and methods for preparing same.

  这项发明涉及在治疗中使用酰基甘油和其氮和硫含量类似物，特别是用于治疗脑缺血。该发明还涉及制备这些衍生物的方法，新颖化合物，特别是酰基甘油，其氮和硫含量类似物以及制备它们的方法。
• Fatty acid compounds, preparation and uses thereof
  申请人：——

  公开号：US20040192908A1

  公开（公告）日：2004-09-30

  The invention concerns novel molecules, their preparation and their uses, in particular in the field of human and veterinary medicine and cosmetics. The inventive compounds are partly fatty acid derivatives and exhibit advantageous pharmacological and cosmetic properties. The invention also concerns various uses of said compounds, the pharmaceutical compositions containing them and methods for preparing them. The inventive compounds are useful in particular for preventing and/or treating dyslipidemiae, cardiovascular diseases, syndrome X, restenosis, diabetes, obesity, hypertension, certain cancers, dermatological diseases and in cosmetics, for fighting against skin aging and its effects notably against wrinkles and the like

  这项发明涉及新颖分子，它们的制备和用途，特别是在人类和兽医医学以及化妆品领域。这些创新化合物部分是脂肪酸衍生物，并具有有利的药理和化妆品特性。该发明还涉及所述化合物的各种用途，含有它们的药物组合物以及制备它们的方法。这些创新化合物特别适用于预防和/或治疗血脂异常、心血管疾病、X综合征、再狭窄、糖尿病、肥胖、高血压、某些癌症、皮肤病以及在化妆品中，用于对抗皮肤衰老及其影响，尤其是对抗皱纹等。
• Rubber compositions having improved processability
  申请人：MONSANTO EUROPE S.A.

  公开号：EP0401193A1

  公开（公告）日：1990-12-05

  Alkylthioalkanoic acids, salts or esters having the formula R¹S(CR³R⁴)xCO₂R² where R¹ represents an alkyl or alkenyl group, or a hydroxy- or alkoxy- substituted alkyl or alkenyl group, said group containing (apart from the alkoxy carbon atoms in an alkoxy-substituted alkyl or alkenyl group) from 4 to 22 carbon atoms, R² represents hydrogen, a metallic or other cationic group, or an esterifying group, each of R³ and R⁴ represents independently hydrogen or an alkyl group, and x has a value of from 1 to 10, act as viscosity-­modifying agents in unvulcanised rubber compositions. Compared with conventional processing aids, they improve the processing characteristics of unvulcanised rubber compositions and can have beneficial effect on the physical properties of vulcanisates obtained by the vulcanisation of such compositions.

  烷基硫代烷酸、盐或酯，其式为 R¹S(CR³R⁴)xCO₂R² 其中，R¹ 代表烷基或烯基，或羟基或烷氧基取代的烷基或烯基，所述基团含有 4 至 22 个碳原子（烷氧基取代的烷基或烯基中的烷氧基碳原子除外）；R² 代表氢、金属或其他阳离子基团或酯化基团；R³ 和 R⁴ 各自独立地代表氢或烷基；x 的值为 1 至 10。与传统加工助剂相比，它们可改善未硫化橡胶组合物的加工特性，并对通过硫化此类组合物获得的硫化胶的物理性质产生有利影响。
• Synthesis and Some Derivatives of 3-Butenenitrile
  作者：JOHN W. LYNN、RICHARD L. ROBERTS、JOHN R. KILSHEIMER

  DOI：10.1021/jo01069a028

  日期：1961.11