ethyl 3-cyclopentyl-5-phenylpentanoate | 1132649-93-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: ethyl 3-cyclopentyl-5-phenylpentanoate
• 英文别名: Ethyl 3-cyclopentyl-5-phenylpentanoate
• CAS: 1132649-93-4
• 化学式: C₁₈H₂₆O₂
• 分子量: 274.403
• InChiKey: OGOZBDAKFNDXNY-UHFFFAOYSA-N

物化性质

• 沸点：
  374.4±21.0 °C(predicted)
• 密度：
  1.012±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  20
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  碘代环戊烷 、 ethyl 5-phenyl-2-pentenoate 在 indium(III) chloride 、 indium 、 copper(l) iodide 作用下， 以 水 为溶剂， 反应 24.0h， 以84%的产率得到ethyl 3-cyclopentyl-5-phenylpentanoate
  参考文献：
  名称：

  Indium/copper-mediated conjugate addition of unactivated alkyl iodides to α,β-unsaturated carbonyl compounds in water

  摘要：

  An efficient method for the conjugate addition of unactivated alkyl iodides to alpha,beta-Unsaturated carbonyl compounds using indium/copper in water is described. The reactions proceed more efficiently in water than in organic solvents. In, CuI, and InCl3 are all essential for efficient reaction. Formation of a symmetrical vic-diarylalkane is observed when an aryl-substituted alkene is used as substrate. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.12.079

文献信息

• Indium/copper-mediated conjugate addition of unactivated alkyl iodides to α,β-unsaturated carbonyl compounds in water
  作者：Zhi-Liang Shen、Hao-Lun Cheong、Teck-Peng Loh

  DOI：10.1016/j.tetlet.2008.12.079

  日期：2009.3

  An efficient method for the conjugate addition of unactivated alkyl iodides to alpha,beta-Unsaturated carbonyl compounds using indium/copper in water is described. The reactions proceed more efficiently in water than in organic solvents. In, CuI, and InCl3 are all essential for efficient reaction. Formation of a symmetrical vic-diarylalkane is observed when an aryl-substituted alkene is used as substrate. (C) 2009 Elsevier Ltd. All rights reserved.