2-(棕榈酰-甲基氨基)乙酸 | 2421-33-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 2-(棕榈酰-甲基氨基)乙酸
• 中文别名: N-十六烷酰肌氨酸；N-甲基-N-苯基-10-(磺酸根氧代)十八烷酰胺酸氢钠
• 英文名称: N-hexadecanoylsarcosine
• 英文别名: N-palmitoyl-sarcosine；N-palmitoylsarcosine；N-methyl-N-palmitoyl-glycine；N-Methyl-N-palmitoyl-glycin；(Methyl-palmitoyl-amino)-essigsaeure；N-Palmitoyl-sarkosin；Palmitoyl sarcosine；2-[hexadecanoyl(methyl)amino]acetic acid
• CAS: 2421-33-2
• 化学式: C₁₉H₃₇NO₃
• 分子量: 327.508
• InChiKey: LFJJOPDNPVFCNZ-UHFFFAOYSA-N

物化性质

• 沸点：
  465.0±28.0 °C(Predicted)
• 密度：
  0.959±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  23
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  57.6
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2924199090

反应信息

• 作为产物：
  描述：

  sodium sarcosinate 、 棕榈酰氯 在 sodium hydroxide 作用下， 反应 1.0h， 生成 2-(棕榈酰-甲基氨基)乙酸
  参考文献：
  名称：

  George, Alex; Modi, Jayesh; Jain, Nirmesh, Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1998, vol. 37, # 11, p. 985 - 992

  摘要：

  DOI：

文献信息

• Preparation of N-acyl amino carboxylic acids, amino carboxylic acids and their derivatives by metal-catalyzed carboxymethylation in the presence of a promoter
  申请人：——

  公开号：US20020058834A1

  公开（公告）日：2002-05-16

  A process for the preparation of amino carboxylic acids, N-acyl amino carboxylic acids, or derivatives thereof by carboxymethylation of an amide, amide precursor or amide source compound in the presence of a carboxymethylation catalyst precursor and a promoter is provided. A carboxymethylation reaction mixture is formed by introducing a promoter, an amide, amide precursor or amide source compound, carbon monoxide, hydrogen, an aldehyde or aldehyde source compound, and a carboxymethylation catalyst precursor into a carboxymethylation reaction zone. In a preferred embodiment, the promoter is a supported noble metal promoter. In another preferred embodiment, the amide compound and aldehyde are selected to yield an N-acyl amino carboxylic acid which is readily converted to N-phosphonomethyl)glycine, or a salt or ester thereof.

  提供了一种通过在存在羧甲基化催化剂前体和促进剂的情况下，通过羧甲基化酰胺、酰胺前体或酰胺源化合物的羧甲基化制备氨基羧酸、N-酰基氨基羧酸或其衍生物的方法。通过将促进剂、酰胺、酰胺前体或酰胺源化合物、一氧化碳、氢气、醛或醛源化合物以及羧甲基化催化剂前体引入羧甲基化反应区域形成羧甲基化反应混合物。在一种首选实施例中，促进剂是支持的贵金属促进剂。在另一种首选实施例中，所选的酰胺化合物和醛可产生一种易于转化为N-磷酸甲基)甘氨酸或其盐或酯的N-酰基氨基羧酸。
• Use of n-acylamino acid compounds as texturing agents
  申请人：Societe d'Exploitation de Produits pour les Industries Chimiques Seppic

  公开号：US06274151B1

  公开（公告）日：2001-08-14

  Use of at least one compound of formula (I): in which R represents the characterizing chain of a saturated or unsaturated, linear or branched fatty acid, comprising from 16 to 22 carbon atoms, represents the characterizing chain or cyclic radical of an amino acid, R2 represents a hydrogen atom or an alkyl radical comprising from 1 to 3 carbon atoms, or the topically acceptable salts thereof, as texturing agents, it being understood that the amino acid characterized by R1 is not lysine, hydroxylysine or arginine. Novel compositions Application in cosmetics.

  至少使用公式（I）中的一个化合物，其中R代表饱和或不饱和，线性或支链脂肪酸的表征链，包括16到22个碳原子，代表氨基酸的表征链或环状基团，R2代表氢原子或由1到3个碳原子组成的烷基基团，或其局部可接受的盐，作为纹理剂。理解R1表征的氨基酸不是赖氨酸，羟基赖氨酸或精氨酸。新颖组合物应用于化妆品。
• GEL COMPOSITION AND NAIL COSMETIC
  申请人：SHISEIDO COMPANY LIMITED

  公开号：EP0379590A1

  公开（公告）日：1990-08-01

  A gel composition and a nail cosmetic are disclosed, which contain one, two or more of cationic surfactants having propylene oxide chain and/or ethylene oxide chain, an organic compound-modified clay mineral, and a solvent. Addition of the above-described specific cationic surfactants serves to well keep thixotropic properties by the organic clay mineral and depress change with time in viscosity and change in viscosity due to slight change in the amount of the organic solvent to an extremely small range.

  本发明公开了一种凝胶组合物和一种指甲化妆品，其中包含一种、两种或两种以上具有环氧丙烷链和/或环氧乙烷链的阳离子表面活性剂、一种有机化合物改性粘土矿物和一种溶剂。添加上述特定的阳离子表面活性剂可以很好地保持有机粘土矿物的触变性能，并将粘度随时间的变化和因有机溶剂量的微小变化而引起的粘度变化控制在极小的范围内。
• Compatibilized internal mold release compositions for preparation of foamed and fiber-reinforced polymeric articles
  申请人：THE DOW CHEMICAL COMPANY

  公开号：EP0490342A2

  公开（公告）日：1992-06-17

  Compositions and a process for preparing a molded foamed polymeric article comprising (1) a relatively high molecular weight polyahl and a relatively low molecular weight polyol, in proportions such that the relatively high molecular weight polyahl and the relatively low molecular weight polyol are incompatible, (2) a polyisocyanate, (3) a blowing agent, and (4) an internal mold release/compatibilizing agent containing (a) a metal salt of a weak acid, wherein the metal is selected from elements of the Periodic Table of the Elements having Atomic Numbers 3-5, 11-14, 19-34, 37-52, 55-57, and 72-84, and (b) a compound containing at least one amine group, wherein the internal mold release/compatibilizing agent is present in an amount sufficient to provide mold release properties to the article and to compatibilize the relatively high molecular weight polyahl and the relatively low molecular weight polyol, are disclosed. In a preferred embodiment the blowing agent is water. The compatibilized compositions exhibit mold release characteristics and also improved adhesion to vinyl-based polymers.

  用于制备模塑发泡聚合制品的组合物和工艺，包括(1)相对高分子量的多元醇和相对低分子量的多元醇，其比例应使相对高分子量的多元醇和相对低分子量的多元醇不相容；(2)多异氰酸酯；(3)发泡剂；(4)内脱模剂/相容剂，其中含有(a)弱酸的金属盐、其中金属选自原子序数为 3-5、11-14、19-34、37-52、55-57 和 72-84 的元素周期表中的元素，以及 (b) 含有至少一个胺基的化合物，其中内部脱模剂/相容剂的存在量足以为制品提供脱模性能，并使相对高分子量的多元醇和相对低分子量的多元醇相容。在一个优选的实施方案中，发泡剂是水。相容后的组合物不仅具有脱模特性，还能改善与乙烯基聚合物的粘附性。
• Base material for cosmetics and uses of the same
  申请人：SEIWA KASEI CO., LTD.

  公开号：EP0699431A1

  公开（公告）日：1996-03-06

  A base material for cosmetics which comprises a silylated peptide of the formual (I): wherein R¹, R² and R³ are the same or different and each is methyl group or hydroxyl group, R⁴ is a group bonding the terminal amino group in a side chain of a basic amino acid to the α-carbon atom wherein the side chain -R⁴NH₂ may partly form an N-heterocyclic ring, R⁵ is a side chain of an amino acid other than the above basic amino acid, A is methylene, propylene, -CH₂OCH₂CH(OH)CH₂- or -(CH₂)₃OCH₂CH(OH)CH₂- group, m is 0 to 100, n is 0 to 100, and m+n is 1 to 100, provided that m and n only show the number of amino acid units, but not amino acid sequence. The silylated peptide (I) is very useful as an additive for hair and skin cosmetics, particularly for aqueous cosmetics, and have excellent pH and storage stabilities and excellent properties such as gloss and moisture impartment to hairs and skins, improvement of combability of hairs, prevention of hairs from being damaged, restoration of damaged hairs, smoothing skin, and the like.

  一种用于化妆品的基质材料，它包含形式为 (I) 的硅烷化肽： 其中，R¹、R² 和 R³ 是相同或不同的基团，每个基团都是甲基或羟基；R⁴ 是将碱性氨基酸侧链中的末端氨基与 α 碳原子结合的基团，其中侧链 -R⁴NH₂ 可部分形成 N-杂环、R⁵ 是上述碱性氨基酸以外的氨基酸侧链，A 是亚甲基、丙烯、-CH₂OCH₂CH(OH)CH₂- 或 -(CH₂)₃OCH₂CH(OH)CH₂- 基团、m 为 0 至 100，n 为 0 至 100，m+n 为 1 至 100，但 m 和 n 仅表示氨基酸单元的数目，而不表示氨基酸序列。硅烷基化肽(I)作为头发和皮肤化妆品的添加剂，尤其是水性化妆品的添加剂非常有用，它具有优异的 pH 值和贮存稳定性，以及诸如头发和皮肤的光泽度和保湿性、改善头发的梳理性、防止头发受损、修复受损头发、平滑皮肤等优异特性。