1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazole-3-carboximidamide | 1354044-23-7

分子结构分类

有机化合物 - 苯类化合物 - 苯和取代衍生物

中文名称

——

中文别名

——

英文名称

1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazole-3-carboximidamide

英文别名

1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazole-3-carboximidamide

1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazole-3-carboximidamide化学式

CAS

1354044-23-7

化学式

C₁₄H₁₂FN₅O

mdl

——

分子量

285.281

InChiKey

VVZILIBRXVGUHY-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

1.4
重原子数：

21
可旋转键数：

4
环数：

3.0
sp3杂化的碳原子比例：

0.07
拓扑面积：

93.7
氢给体数：

2
氢受体数：

5

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	ethyl 1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazole-3-carboxylate	1354044-05-5	C₁₆H₁₄FN₃O₃	315.304

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)-pyrimidin-4-amine	1354041-25-0	C₁₇H₁₃FN₆O	336.328
——	2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidin-4-ol	1354041-90-9	C₁₇H₁₂FN₅O₂	337.313
——	5-fluoro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidin-4-amine	1354041-37-4	C₁₇H₁₂F₂N₆O	354.319
——	3-(3-(4-chloro-5-fluoropyrimidin-2-yl)-1-(2-fluorobenzyl)-1H-pyrazol-5-yl)isoxazole	1446358-48-0	C₁₇H₁₀ClF₂N₅O	373.749
——	[5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]hydrazine	1446358-50-4	C₁₇H₁₃F₂N₇O	369.333
——	3-(3-(4,6-dichloro-5-fluoropyrimidin-2-yl)-1-(2-fluorobenzyl)-1H-pyrazol-5-yl)isoxazole	1446359-43-8	C₁₇H₉Cl₂F₂N₅O	408.194
——	2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile	1354041-38-5	C₁₈H₁₁FN₆O₂	362.323
——	5-fluoro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)-pyrimidin-4-ol	1354041-91-0	C₁₇H₁₁F₂N₅O₂	355.303
——	3-[5-(5-Bromo-4-chloropyrimidin-2-yl)-2-[(2-fluorophenyl)methyl]pyrazol-3-yl]-1,2-oxazole	1446358-80-0	C₁₇H₁₀BrClFN₅O	434.655
——	3-(3-(5-fluoro-4-methoxypyrimidin-2-yl)-1-(2-fluorobenzyl)-1H-pyrazol-5-yl)isoxazole	1446358-49-1	C₁₈H₁₃F₂N₅O₂	369.33
——	[4-Amino-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-5-yl] 1-methylcyclopropane-1-carboxylate	1446358-79-7	C₂₂H₁₉FN₆O₃	434.43
——	5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidine-4-carbonitrile	1446359-52-9	C₁₈H₁₀F₂N₆O	364.314
——	4-chloro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidine-5-sulfonyl chloride	1446358-84-4	C₁₇H₁₀Cl₂FN₅O₂	406.203
——	2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)-5-(4-fluorophenylthio)pyrimidin-4-ol	1446358-64-0	C₂₃H₁₅F₂N₅O₂S	463.467
——	2-[5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]acetonitrile	1446359-60-9	C₁₉H₁₂F₂N₆O	378.341
——	4-chloro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidine-5-sulfonyl chloride	1446359-92-7	C₁₇H₁₀Cl₂FN₅O₃S	454.269
——	N-(2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)-4-hydroxypyrimidin-5-yl)benzamide	1354041-88-5	C₂₄H₁₇FN₆O₃	456.436
——	2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)-4-hydroxypyrimidine-5-sulfonyl chloride	1354044-11-3	C₁₇H₁₁ClFN₅O₄S	435.823
——	5-fluoro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidine-4,6-diol	——	C₁₇H₁₁F₂N₅O₃	371.303
——	2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]-5-(1,3-thiazol-2-yl)-1H-pyrimidin-6-one	1446358-92-4	C₂₀H₁₃FN₆O₂S	420.427
——	2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)-5-(2-hydroxypropan-2-yl)pyrimidin-4-ol	1354041-62-5	C₂₀H₁₈FN₅O₃	395.393
——	2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)-5-(pyridin-2-ylthio)pyrimidin-4-ol	1446358-67-3	C₂₂H₁₅FN₆O₂S	446.465
——	2-morpholinoethyl (5-fluoro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidin-4-yl)carbamate	——	C₂₄H₂₃F₂N₇O₄	511.488
——	2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]-5-(1,3-oxazol-2-yl)-1H-pyrimidin-6-one	1446358-94-6	C₂₀H₁₃FN₆O₃	404.36
——	2,2-Difluoro-3-[[5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]amino]propanoic acid	——	C₂₀H₁₄F₄N₆O₃	462.363
——	2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]-5-pyridin-2-yl-1H-pyrimidin-6-one	1446358-90-2	C₂₂H₁₅FN₆O₂	414.399
——	3-[5-(5-Bromo-4-phenylmethoxypyrimidin-2-yl)-2-[(2-fluorophenyl)methyl]pyrazol-3-yl]-1,2-oxazole	1446358-85-5	C₂₄H₁₇BrFN₅O₂	506.334
——	4-chloro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidine-5-sulfonyl chloride	1446358-81-1	C₁₉H₁₇FN₆O₄S	444.446
——	2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]-5-thiophen-3-yl-1H-pyrimidin-6-one	1446358-88-8	C₂₁H₁₄FN₅O₂S	419.439
——	3-(3-(4-chloro-5-fluoro-6-methoxypyrimidin-2-yl)-1-(2-fluorobenzyl)-1H-pyrazol-5-yl)isoxazole	1446359-44-9	C₁₈H₁₂ClF₂N₅O₂	403.775
——	6-fluoro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)-5-(trifluoromethyl)pyrimidin-4(3H)-one	1446358-51-5	C₁₈H₁₀F₅N₅O₂	423.302
——	5-(4-chlorophenylsulfonyl)-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidin-4(3H)-one	——	C₂₃H₁₅ClFN₅O₄S	511.921
——	3-[5-[5-Bromo-4-[(4-methoxyphenyl)methoxy]pyrimidin-2-yl]-2-[(2-fluorophenyl)methyl]pyrazol-3-yl]-1,2-oxazole	1446358-86-6	C₂₅H₁₉BrFN₅O₃	536.36
——	1-(5-fluoro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidin-4-yl)piperidine-4-carboxylic acid	——	C₂₃H₂₀F₂N₆O₃	466.447
——	3,3,3-trifluoro-2-(((5-fluoro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidin-4-yl)amino)methyl)-2-hydroxypropanamide	——	C₂₁H₁₆F₅N₇O₃	509.395
——	3,3,3-Trifluoro-2-[[[5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]amino]methyl]-2-hydroxypropanoic acid	——	C₂₁H₁₅F₅N₆O₄	510.38
——	4-chloro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidine-5-sulfonyl chloride	1446358-82-2	C₂₁H₁₉FN₆O₄S	470.484
——	N-benzyl-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]-N-methyl-6-oxo-1H-pyrimidine-5-sulfonamide	1446358-73-1	C₂₅H₂₁FN₆O₄S	520.544
——	3-[2-[(2-Fluorophenyl)methyl]-5-[4-[(4-methoxyphenyl)methoxy]-5-thiophen-3-ylpyrimidin-2-yl]pyrazol-3-yl]-1,2-oxazole	1446358-87-7	C₂₉H₂₂FN₅O₃S	539.59
——	4-[6-Chloro-5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]morpholine	——	C₂₁H₁₇ClF₂N₆O₂	458.855