N-phenyl-2-(phenylthio)benzamide | 109806-80-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-phenyl-2-(phenylthio)benzamide
• 英文别名: N-phenyl-2-phenylsulfanylbenzamide
• CAS: 109806-80-6
• 化学式: C₁₉H₁₅NOS
• 分子量: 305.4
• InChiKey: BFWCYMMSVLVGOR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-phenyl-2-(phenylthio)benzamide 在 双氧水 、 溶剂黄146 作用下， 生成 2-benzenesulfonyl-benzoic acid anilide
  参考文献：
  名称：

  Adams et al., Croatica Chemica Acta, 1957, vol. 29, p. 277,284, 285

  摘要：

  DOI：
• 作为产物：
  描述：

  2-苯基-1,2-苯并噻唑-3-酮 、 phenylmagnesium bromide 以 四氢呋喃 为溶剂， 反应 1.0h， 以79%的产率得到N-phenyl-2-(phenylthio)benzamide
  参考文献：
  名称：

  Reactions of N-sulfenyl-1,2-benzisothiazolin-3-ones with nucleophiles

  摘要：

  Reactions of N-[2-(alkoxycarbonyl)benzenesulfenyl]-1,2-benzisothiazolin-3-ones (1) with various nucleophiles were examined. Anions of active methylene compounds attacked the sulfur atoms of the suffenyl moieties of I to afford sulfide compounds, while thiols attacked the sulfur atoms of the benzisothiazolinone moieties of 1 to afford ring-opened products. Grignard reagents attacked both the above sulfur atoms to give ring-opened products along with sulfide compounds. (C) 2004 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tet.2004.09.093

文献信息

• Adams et al., Croatica Chemica Acta, 1957, vol. 29, p. 277,284, 285
  作者：Adams et al.

  DOI：——

  日期：——
• Reactions of N-sulfenyl-1,2-benzisothiazolin-3-ones with nucleophiles
  作者：Ming Bao、Masao Shimizu、Shigeru Shimada、Jun'ichi Inoue、Takeo Konakahara

  DOI：10.1016/j.tet.2004.09.093

  日期：2004.12

  Reactions of N-[2-(alkoxycarbonyl)benzenesulfenyl]-1,2-benzisothiazolin-3-ones (1) with various nucleophiles were examined. Anions of active methylene compounds attacked the sulfur atoms of the suffenyl moieties of I to afford sulfide compounds, while thiols attacked the sulfur atoms of the benzisothiazolinone moieties of 1 to afford ring-opened products. Grignard reagents attacked both the above sulfur atoms to give ring-opened products along with sulfide compounds. (C) 2004 Published by Elsevier Ltd.