phenyl[1-(4-tolylethyl)]selane | 103971-87-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: phenyl[1-(4-tolylethyl)]selane
• 英文别名: 1-Methyl-4-(1-phenylselanylethyl)benzene
• CAS: 103971-87-5
• 化学式: C₁₅H₁₆Se
• 分子量: 275.252
• InChiKey: XWVXUCYVJLZTGS-UHFFFAOYSA-N

物化性质

• 沸点：
  353.9±35.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.09
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  phenyl[1-(4-tolylethyl)]selane 在 sodium phosphite 、 Thermobifida fusca recombinant phenylacetone monooxygenase 、 phosphite dehydrogenase 、 NADP+ 作用下， 以 二甲基亚砜 为溶剂， 反应 8.0h， 以9%的产率得到
  参考文献：
  名称：

  Chemoenzymatic approaches to obtain chiral-centered selenium compounds

  摘要：

  The synthesis of chiral-centered selenium compounds is presented. Enantioselective oxidations of these organoselenium compounds were performed using a wide range of biocatalysts, including Baeyer-Villiger monooxygenases, oxidoreductases-containing Aspergillus terreus and lipase (Cal-B) in the presence of oxidants. Finally, efficient synthesis of enantiopure organoselenium compounds using a kinetic resolution approach mediated by Cal-B was achieved. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.09.087
• 作为产物：
  描述：

  溴苯 在 zinc(II) chloride selenium 、 magnesium 作用下， 以 四氯化碳 为溶剂， 反应 1.5h， 生成 phenyl[1-(4-tolylethyl)]selane
  参考文献：
  名称：

  Synthesis of selenoacetals

  摘要：

  DOI：

  10.1016/s0040-4020(01)96719-5

文献信息

• A Facile Method for Synthesis of Alkyl Phenyl Selenides. The Reaction of Diphenyl Diselenide with Oxygen-containing Compounds Using La/Me₃SiCl/^cat.I₂/^cat.CuI System
  作者：Toshiki Nishino、Yutaka Nishiyama、Noboru Sonoda

  DOI：10.1246/cl.2003.918

  日期：2003.10

  Alcohols, ethers, and esters were directly converted to the corresponding alkyl phenyl selenides by the reaction of diphenyl diselenide and the La/Me3SiCl/cat.I2/cat.CuI. It was suggested that alkyl phenyl selenides were formed by the SH2 type reaction of diphenyl diselenide with alkyl radicals generated from alcohols, ethers or esters.

  通过二苯基二硒化物和 La/Me3SiCl/cat.I2/cat.CuI 的反应，醇、醚和酯直接转化为相应的烷基苯基硒化物。有人提出烷基苯基硒化物是由二苯基二硒化物与醇、醚或酯产生的烷基自由基的SH2型反应形成的。
• Synthesis of selenoacetals
  作者：M. Clarembeau、A. Cravador、W. Dumont、L. Hevesi、A. Krief、J. Lucchetti、D. Van Ende

  DOI：10.1016/s0040-4020(01)96719-5

  日期：1985.1
• Chemoenzymatic approaches to obtain chiral-centered selenium compounds
  作者：Patrícia B. Brondani、Nathalie M.A.F. Guilmoto、Hanna M. Dudek、Marco W. Fraaije、Leandro H. Andrade

  DOI：10.1016/j.tet.2012.09.087

  日期：2012.12

  The synthesis of chiral-centered selenium compounds is presented. Enantioselective oxidations of these organoselenium compounds were performed using a wide range of biocatalysts, including Baeyer-Villiger monooxygenases, oxidoreductases-containing Aspergillus terreus and lipase (Cal-B) in the presence of oxidants. Finally, efficient synthesis of enantiopure organoselenium compounds using a kinetic resolution approach mediated by Cal-B was achieved. (C) 2012 Elsevier Ltd. All rights reserved.