2-[(2,5-二甲基苯氧基)甲基]环氧乙烷 | 4287-29-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 2-[(2,5-二甲基苯氧基)甲基]环氧乙烷
• 英文名称: (2,5-dimethyl-phenoxymethyl)-oxirane
• 英文别名: 2-[(2,5-Dimethylphenoxy)methyl]oxirane
• CAS: 4287-29-0
• 化学式: C₁₁H₁₄O₂
• mdl: MFCD06655561
• 分子量: 178.231
• InChiKey: PGSFTJDYQSZEKZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.454
• 拓扑面积：
  21.8
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2910900090

反应信息

• 作为反应物：
  描述：

  2-[(2,5-二甲基苯氧基)甲基]环氧乙烷 、 3-(2-amino-2-methylpropoxy)-6-chloropyridazine 以 叔丁醇 为溶剂， 反应 8.0h， 生成 1-(2,5-Dimethylphenoxy)-3-[1,1-dimethyl-2-(3-chloro-6-pyridazinyloxy)ethylamino]-2-propanol
  参考文献：
  名称：

  Studies on Agents with Vasodilator and .BETA.-Blocking Activities. II.

  摘要：

  一系列含有哒嗪基肼结构的苯氧丙醇胺类化合物被合成，并通过静脉注射给麻醉大鼠后评估了它们的降压和β阻断活性。其中一些化合物显示了这两种活性。特别是化合物20k，由于其降压活性与肼达嗪相当，且β阻断活性比普萘洛尔强2.7倍，因此被认为是临床应用的候选药物。

  DOI：

  10.1248/cpb.43.247

文献信息

• Studies on Agents with Vasodilator and ,B-Blocking Activities. IV.
  作者：Toshimi SEKI、Tomio NAKAO、Takeshi MASUDA、Kohichi HASUMI、Kotaro GOTANDA、Tsutomu ISHIMORI、Seijiro HONMA、Nobuyoshi MINAMI、Kenyu SHIBATA、Kikuo YASUDA

  DOI：10.1248/cpb.44.2061

  日期：——

  A series of novel pyridazinone derivatives (II) having a phenoxypropanolamine moiety was synthesized. Their hypotensive and β-blocking activities were evaluated after intravenous administration of the compounds to anesthetized rats. Among them, the 5-chloro-2-cyanophenoxy derivative (29) showed the promising dual activities and was selected for further studies.

  合成了一系列具有苯氧基丙醇胺结构的新型哒嗪酮衍生物（II）。在静脉注射给麻醉大鼠后，评估了它们的降压和β-阻断活性。其中，5-氯-2-氰基苯氧基衍生物（29）显示出有前途的双重活性，并被选中进行进一步研究。
• Polymer electrolyte and method for producing the same
  申请人：——

  公开号：US20010041279A1

  公开（公告）日：2001-11-15

  Provided is a polymer electrolyte containing a block copolymer comprising one or more blocks having sulfonic acid groups and one or more blocks having substantially no sulfonic acid group, and at least one block among all blocks is a block having aromatic rings in the main chain thereof, and a method for producing the same. The polymer electrolyte is suitable for a proton conductive film of a fuel cell due to excellent water resistance and heat resistance, and high proton conductivity.

  提供的是一种聚合物电解质，包含一种嵌段共聚物，其中包括一个或多个具有磺酸基团的块和一个或多个几乎没有磺酸基团的块，而所有块中至少有一个块具有其主链中的芳香环，以及其制备方法。由于具有优异的耐水性、耐热性和高质子传导性，该聚合物电解质适用于燃料电池的质子传导膜。
• Polymer electrolyte
  申请人：Sumitomo Chemical Company Limited

  公开号：EP2461413A1

  公开（公告）日：2012-06-06

  Provided is a polymer electrolyte containing a block copolymer comprising one or more blocks having sulfonic acid groups and one or more blocks having substantially no sulfonic acid group, and at least one block among all blocks is a block having aromatic rings in the main chain thereof, and a method for producing the same. The polymer electrolyte is suitable for a proton conductive film of a fuel cell due to excellent water resistance and heat resistance, and high proton conductivity.

  本发明提供了一种聚合物电解质，它含有一种嵌段共聚物，该嵌段共聚物由一个或多个具有磺酸基团的嵌段和一个或多个基本上没有磺酸基团的嵌段组成，所有嵌段中至少有一个嵌段是主链上具有芳香环的嵌段，还提供了生产这种聚合物电解质的方法。该聚合物电解质具有优异的耐水性、耐热性和高质子传导性，适用于燃料电池的质子传导膜。
• DE1236523
  申请人：——

  公开号：——

  公开（公告）日：——
• Epoxy Resin Composition,Cured Article Thereof, Semiconductor Sealing Material, Novel Phenol Resin, Novel Epoxy Resin,Method for Producing Novel Phenol Resin, And Method For Producing Novel Epoxy Resin
  申请人：Ogura Ichiro

  公开号：US20080255315A1

  公开（公告）日：2008-10-16

  An epoxy resin composition including an epoxy resin and a curing agent as essential components, in which the curing agent comprises a phenol resin which has each structural moiety of a phenolic hydroxyl group-containing aromatic hydrocarbon group (P), an alkoxy group-containing aromatic hydrocarbon group (B) and a divalent aralkyl group (X), and also has, in a molecular structure, a structure in which the phenolic hydroxyl group-containing aromatic hydrocarbon group (P) and the alkoxy group-containing aromatic hydrocarbon group (B) are bonded with the other phenolic hydroxyl group-containing aromatic hydrocarbon group (P) or alkoxy group-containing aromatic hydrocarbon group (B) via the divalent aralkyl group (X).