Zinc-EDTA | 12519-36-7

• 物质功能分类: 催化剂及助剂 - 贵金属催化剂
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Zinc-EDTA
• 英文别名: dizinc;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate
• CAS: 12519-36-7
• 化学式: C10H12N2O8Zn2
• 分子量: 419.0
• InChiKey: WHYUWYVXDNNLTR-UHFFFAOYSA-J

计算性质

• 辛醇/水分配系数(LogP)：
  -7.42
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  167
• 氢给体数：
  0
• 氢受体数：
  10

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26
• 危险类别码：
  R36
• 储存条件：
  室温，惰性气体

文献信息

• SAMPLE FIXATION AND STABILISATION
  申请人：Goldsborough Andrew Simon

  公开号：US20140295404A1

  公开（公告）日：2014-10-02

  It has surprisingly been discovered that it is possible to stabilise biomolecules such as RNA, DNA and proteins in biological samples such as cells, tissues, biopsies and blood using deep eutectic solvents (DES). It has also been discovered that DES mixtures can be used to fix and preserve cell morphology in biological samples such as tissue blocks, cancer biopsies and whole blood. This invention describes methods to stabilise and preserve biomolecules, whole cells, tissues, blood and biological samples using DES mixtures.

  令人惊讶地发现，使用深共熔溶剂（DES）可以稳定生物样本中的生物分子，如RNA、DNA和蛋白质，例如细胞、组织、活检和血液。同时，也发现DES混合物可以用于固定和保护生物样本中的细胞形态，例如组织块、癌症活检和全血。本发明描述了使用DES混合物稳定和保护生物分子、整个细胞、组织、血液和生物样本的方法。
• Verfahren zur Stabilisierung der alkalischen Phosphatase
  申请人：MERCK PATENT GmbH

  公开号：EP0042969A1

  公开（公告）日：1982-01-06

  Die Erfindung betrifft Verfahren und Mittel zur Stabilisierung der alkalischen Phosphatase in Pufferlösungen. Zu diesem Zweck wird der Pufferlösung ein wasserlöslicher Komplex aus Zinkionen und einem Chelatbildner zugesetzt.

  本发明涉及在缓冲溶液中稳定碱性磷酸酶的方法和手段。为此，在缓冲溶液中加入锌离子和螯合剂的水溶性复合物。
• Chelated plant nutrients
  申请人：ACTAGRO, INC.

  公开号：EP0284339A2

  公开（公告）日：1988-09-28

  Liquid micronutrient compositions are pre­pared by combining fulvic acid extracted from leonardite ore with a metal salt, a hydroxy acid and/or a hydroxy acid salt, and ammonia. The extract of leonardite ore is obtained by combination with a suitable chelant, while the subsequent combination with the metal salt and hydroxy acid/salt is accomplished in a heated aqueous medium. After allowing the desired metal chelates to form, the composition is combined with anhydrous ammonia, usually by sparging, to obtain a stable end product. The micronutrient compositions display enhanced plant uptake in both soil and foliar applications. Moreover, the compositions are particu­larly stable and suitable for application through drip irrigation systems.

  液体微量营养素组合物的制备方法是从褐铁矿中提取的富勒酸与金属盐、羟基酸和/或羟基酸盐以及氨结合在一起。褐铁矿提取物通过与合适的螯合剂结合获得，而随后与金属盐和羟基酸/盐的结合则在加热的水介质中完成。在形成所需的金属螯合物后，将组合物与无水氨（通常是通过喷射）结合，以获得稳定的最终产品。微量营养元素组合物在土壤和叶面应用中都能提高植物的吸收率。此外，这种组合物特别稳定，适合通过滴灌系统施用。
• Glass ionomer dental cement curable in two stages
  申请人：Kerr Manufacturing Company (a Delaware corporation)

  公开号：EP0329268A2

  公开（公告）日：1989-08-23

  A series of dual curing dental cements are disclosed which consist of powder and liquid components to be mixed within a preferred powder to liquid range by weight. Mixing is initiated immediately prior to usage following which the mixed material is applied to the tooth surface as required and cured within a few seconds by irradiation with high intensity visible light energy to a tough leathery consistency, thus permitting the bulk placement of other dental restoratives over it without disturbance. The second stage curing, which is chemically initiated, occurs much more slowly between the powder and the liquid and results in a fully set cement which is hard and rigid. These cements are adhesive, both to prepared tooth structure and to composite dental restorative materials bulk placed over them. Thus, they combine the advantages of conventional dental glass ionomer cements with those of a first generation visible light cured cavity liner.

  本发明公开了一系列双重固化牙科水门汀，由粉末和液体成分组成，按重量计，粉末与液体的混合比例为优选范围。在使用前立即开始混合，然后根据需要将混合材料涂抹在牙齿表面，并通过高强度可见光照射在几秒钟内固化成坚韧的皮革状，从而允许在其上大量放置其他牙科修复材料而不受干扰。第二阶段的固化是化学反应，在粉末和液体之间进行，速度要慢得多，最终形成坚硬的完全固化水门汀。 这些水门汀具有粘接性，既能粘接制备好的牙齿结构，也能粘接置于其上的大量复合牙科修复材料。因此，这些水门汀结合了传统牙科玻璃离聚体水门汀和第一代可见光固化空腔衬垫的优点。
• Stabilization of isothiazolones
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0425143A2

  公开（公告）日：1991-05-02

  A composition comprising (a) One or more 3-isothiazolones of the formula: wherein Y is a (C₁-C₁₈)alkyl or (C₃-C₁₂), preferably (C₅-C₈), cycloalkyl each optionally substituted with one or more of hydroxy, halo, cyano, alkylamino, dialkylamine, arylamino, carboxy, carbalkoxy, alkoxy, aryloxy, alkylthio, haloalkoxy, cycloalkylamino, carbamoxy, or isothiazolonyl; an unsubstituted or halo-substituted (C₂-C₈), preferably (C₂-C₄) alkenyl or alkynyl; a (C₇-C₁₀)aralkyl optionally substituted with one or more of halogen, (C₁-C₄)alkyl or (C₁-C₄)alkoxy; or an aryl optionally substituted with one or more of halogen, nitro, (C₁-C₄)alkyl, (C₁-C₄)alkyl-acylamino, carb(C₁-C₄)alkoxy or sulfamyl; and X and X₁ are each independently hydrogen, chloro, or methyl; and (b) a metal salt comprising a copper, zinc, manganese, ferrous or ferric salt, the anion of which is an organic carboxylic acid of at least six carbon atoms, EDTA, 8-hydroxyquinolinate, gluconate, o-phenanthroline, quinolinate N,N-bis(2-hydroxy-5-sulfobenzyl) glycine, a lignosulfonate polymer, or a polyacrylate; and (c) a locus to be protected against the growth of algae, bacteria, or fungi, said locus being of: (i) a metal working fluid (MWF) comprising at least one component selected from the group consisting of an alkanolamine, a petroleum sulfonate emulsifier, a boric acid ester or boric acid amide, a corrosion inhibitor, and a fatty acid; (ii) cooling tower water comprising corrosion inhibitors or scale inhibitors; (iii) laundry dish water; (iv) a cosmetic formulation; (v) a fuel system; (vi) an emulsion; (vii) a solid protective or decorative film; (viii) a film-forming, substantially non-wood-penetrating, organic polymeric paint vehicle in the case where the salt is a manganese, ferrous or ferric salt is disclosed, together with a method of stabilizing 3-isothiazolones in such loci using said metal salts.

  一种组合物，包括 (a) 一种或多种 3-异噻唑酮，其式如下 其中 Y 是(C₁-C₁₈)烷基或(C₃-C₁₂)，优选(C₅-C₈)，环烷基，每个环烷基任选被羟基、卤代、氰基中的一个或多个取代、烷基氨基、二烷基胺、芳基氨基、羧基、碳烷氧基、烷氧基、芳氧基、烷硫基、卤代烷氧基、环烷基氨基、氨基甲氧基或异噻唑基；未取代或卤代取代的(C₂-C₈)，最好是(C₂-C₄)烯基或炔基；任选被卤素、(C₁-C₄)烷基或(C₁-C₄)烷氧基中的一个或多个取代的(C₇-C₁₀)芳烷基；或任选被卤素、硝基、(C₁-C₄)烷基、(C₁-C₄)烷基-酰氨基、碳(C₁-C₄)烷氧基或氨基磺酰基中的一个或多个取代的芳基；以及 X 和 X₁ 各自独立地为氢、氯或甲基；以及 (b) 金属盐，包括铜盐、锌盐、锰盐、亚铁盐或铁盐，其阴离子为至少含 6 个碳原子的有机羧酸、乙二胺四乙酸、8-羟基喹啉酸盐、葡萄糖酸盐、邻菲罗啉、喹啉酸盐、N,N-双（2-羟基-5-磺酸基苄基）甘氨酸、木质素磺酸盐聚合物或聚丙烯酸酯；以及 (c) 需要防止藻类、细菌或真菌生长的基因座，所述基因座属于以下物质： (i) 金属加工液 (MWF)，包括至少一种选自以下组别的成分：烷醇胺、石油磺酸盐乳化剂、硼酸酯或硼酸酰胺、缓蚀剂和脂肪酸； (ii) 含有缓蚀剂或阻垢剂的冷却塔水； (iii) 洗碗水 (iv) 化妆品配方 (v) 燃料系统 (vi) 一种乳液 (vii) 固体保护膜或装饰膜； (viii) 成膜的、基本上不渗透木材的有机聚合涂料载体，其中盐为锰、亚铁或铁 盐 本发明公开了 3-异噻唑啉酮类化合物，以及使用上述金属盐在这些位置稳定 3-异噻唑啉酮类化合物的方法。