3-tert-butyl-2-hydroxybenzyl bromide | 1072238-39-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-tert-butyl-2-hydroxybenzyl bromide
• 英文别名: 3-tert-butyl-2-hydroxybenzylbromide；2-Hydroxy-3-t-butyl-benzylbromide；2-(bromomethyl)-6-tert-butylphenol
• CAS: 1072238-39-1
• 化学式: C₁₁H₁₅BrO
• 分子量: 243.143
• InChiKey: MOOMNUVQRHXGEV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3-tert-butyl-2-hydroxybenzyl bromide 、 二甲基吡啶胺 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 以82%的产率得到[N-(3-tert-butyl-2-hydroxybenzyl)-N,N-di-(2-pyridylmethyl)]amine
  参考文献：
  名称：

  Mononuclear iron(III) complexes supported by tripodal N3O ligands: Synthesis, structure and reactivity towards DNA cleavage

  摘要：

  A new synthetic route to the known tripodal tetradentate N3O ligand L-1 (HL1 = [N-(3,5-di-tert-butyl-2-hydroxybenzyl)-N,N-di-(2-pyridylmethyl)]amine) is reported. The related compounds HLn (n = 2, 3) were prepared by a similar procedure. Treatment of HLn (n = 1-3) with FeCl3 center dot 6H(2)O in hot methanol led to the mononuclear iron(III) complexes [Fe(Ln)Cl-2] (1: n = 1, 2: n = 2, 3: n = 3). The solid-state structures of complexes 1 and 2 were determined by X-ray crystallography. [Fe(L-1)Cl-2] (1) showed effective nuclease activity in the presence of hydrogen peroxide, converting supercoiled plasmid DNA to its linear form. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2009.12.039
• 作为产物：
  描述：

  2-叔丁基苯酚 在 sodium tetrahydroborate 、 三正丁胺 、 三溴化磷 、 四氯化锡 作用下， 以 甲醇 、 氯仿 、 甲苯 为溶剂， 生成 3-tert-butyl-2-hydroxybenzyl bromide
  参考文献：
  名称：

  具有N封端的三脚架N 2 O 2四齿配体的 新型二氧钼（vi）和钨（vi）配合物：合成，结构和对烯烃环氧化的催化活性†

  摘要：

  源自di- /的一系列N 2 O 2三脚架四齿配体四叔丁基 替代的 2- [双（2-羟基苄基）氨基甲基] X （X = 吡啶 和 苯并咪唑）（H 2 L n（n = 1-4））和8- [双（3,5-二叔丁基-2-羟基苄基）]氨基喹啉（H 2 L 5）是通过4步反应流程合成的，该流程涉及顺序的甲酰化，还原，溴化和烷基化。用[WO 2 Cl 2（dme）]处理H 2 L n（n = 1-5）（dme = 1,2-二甲氧基乙烷） 在......的存在下 三乙胺 给了相应的 顺式-二氧杂钨（VI）络合物[WO 2（L n）]（n = 1-5）。相应的钼类似物[的MoO 2（L Ñ）]（Ñ = 1-5）也从[的MoO的反应来制备2（ACAC）2 ]（ACAC =乙酰丙酮）与H 2 L n（n = 1-3）或[MoO 2 Cl 2（dme）]（dme = 1,2-二甲氧基乙烷）且H 2 L n（n =

  DOI：

  10.1039/b926864b

文献信息

• Synthesis, structures and catalytic properties of iron(iii) complexes with asymmetric N-capped tripodal NO3 ligands and a pentadentate N2O3 ligand
  作者：Lok H. Tong、Yee-Lok Wong、Sofia I. Pascu、Jonathan R. Dilworth

  DOI：10.1039/b804414g

  日期：——

  [Fe(L(5))] (5). All complexes were structurally characterised by X-ray crystallography. In complexes 1-4, the ligands form five- and six-membered chelate rings with the iron centres which have distorted trigonal bipyramidal geometry with an N(2)O(3) coordination environment. Complex 5 adopts a similar distorted trigonal bipyramidal geometry also with N(2)O(3) coordination around the iron centre. The catalytic

  N封顶的三脚架NO（3）配体的新家族N，N-双（2-羟基-3,5-二叔丁基苄基）-N-（2'-羟基-5'-R-苯基）胺[H（3）（L（n））] [当R = Me时，n = 1；R =（t）Bu，n = 2；R = Cl，n = 3]在一个芳环和N，N-双（2-羟基-3-叔丁基苄基）-N-（2'-羟基-5'-甲基苯基）胺中具有不同的取代基H（3）（L（4））]已合成。一种新的五齿配体N-甲基-N，N'，N'-三（2-羟基-3,5-二叔丁基苄基）乙烷-1,2-二胺[H（3）（L（ 5））]也有N（2）O（3）供体组。配体[H（3）（L（n））]（n = 1-4）与氯化铁（III）在碱（三乙胺）和1-甲基咪唑（1-Meim）共配体存在下的反应导致分别形成[Fe（L（n））（1-Meim）]（n = 1-4）（1-4）类型的铁络合物，同时用氯化铁（III）处理[H（3）（L（5））]三锂盐可制得[
• [EN] SALALEN LIGANDS AND ORGANOMETALLIC COMPLEXES<br/>[FR] LIGANDS DE SALALÈNE ET COMPLEXES ORGANOMÉTALLIQUES
  申请人：UNIV RAMOT

  公开号：WO2011158241A1

  公开（公告）日：2011-12-22

  Use of homogeneous catalytic systems which include as a pre-catalyst a complex of a Group IV metal and a salalen ligand in the polymerization of alpha-olefins, is disclosed. The alpha-olefin polymers obtained are characterized by controlled levels of tacticity. Also disclosed are novel salalen ligands and novel complexes thereof with Group IV metals.

  本发明揭示了在α-烯烃聚合中使用包括群四金属和Salalen配体复合物作为前催化剂的均相催化体系。所得的α-烯烃聚合物具有受控的立构度水平。还公开了新型Salalen配体以及与群四金属形成的新型配合物。
• METAL COMPLEXES OF SALAN-TYPE LIGANDS AND USES THEREOF AS CATALYSTS FOR POLYMERIZATION OF ALPHA-OLEFINS
  申请人：Kol Moshe

  公开号：US20130310529A1

  公开（公告）日：2013-11-21

  Use of homogeneous catalytic systems which include as a pre-catalyst a complex of a group 4 metal and a Salan ligand in the polymerization of alpha-olefins, is disclosed. The Salan ligand is characterized by a sequential diamino-containing skeleton unit which is non-symmetric, and the pre-catalysts can also be such that are devoid of a symmetry element. The disclosed polymerization results in alpha-olefin polymers such as polypropylene which are characterized by high levels of tacticity. Also disclosed are novel Salan ligands and novel complexes thereof with group 4 metals.

  揭示了在α-烯烃聚合中使用包括第4族金属和Salan配体的预催化剂的均相催化体系的用途。Salan配体的特点是具有非对称的顺序二氨基骨架单元，预催化剂也可以是不具有对称元素的。所揭示的聚合产物为α-烯烃聚合物，例如高度具有定向性的聚丙烯。还揭示了新型的Salan配体及其与第4族金属的新配合物。
• SALALEN LIGANDS AND ORGANOMETALLIC COMPLEXES
  申请人：Kol Moshe

  公开号：US20130096271A1

  公开（公告）日：2013-04-18

  Use of homogeneous catalytic systems which include as a pre-catalyst a complex of a Group IV metal and a salalen ligand in the polymerization of alpha-olefins, is disclosed. The alpha-olefin polymers obtained are characterized by controlled levels of tacticity. Also disclosed are novel salalen ligands and novel complexes thereof with Group IV metals.

  揭示了在α-烯烃聚合中使用包括一种Group IV金属和一种salalen配体的前催化剂的均相催化系统。所获得的α-烯烃聚合物具有可控的立构性水平。还揭示了新型的salalen配体及其与Group IV金属的新型配合物。
• US8907032B2
  申请人：——

  公开号：US8907032B2

  公开（公告）日：2014-12-09