4,4'''-diamino-o-quaterphenyl | 212002-63-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,4'''-diamino-o-quaterphenyl
• 英文别名: [1,1';2',1'';2'',1''']quaterphenyl-4,4'''-diyldiamine；[1,1';2',1'';2'',1''']Quaterphenyl-4,4'''-diyldiamin；o-Quaterphenyldiyl-(4.4''')-diamin；4.4'''-Diamino-o-quaterphenyl；4.4'''-Diamino-[2'.2'']quaterphenyl；4-[2-[2-(4-Aminophenyl)phenyl]phenyl]aniline
• CAS: 212002-63-6
• 化学式: C₂₄H₂₀N₂
• 分子量: 336.436
• InChiKey: RSNQFSRZWXDXSI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  52
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4,4'''-diamino-o-quaterphenyl 在 盐酸 、 potassium iodide 、 sodium nitrite 作用下， 生成 4,4'''-diiodo-o-quaterphenyl
  参考文献：
  名称：

  Syntheses and physical properties of several octiphenyls containing mixed linkages.

  摘要：

  通过碘四联苯的Ullmann同系偶联反应合成了8个新型线性八联苯，包含2种或3种连接方式。其中5个化合物是通过双(乙酰丙酮)镍(II)催化的二碘四联苯和联苯基溴化镁或三联苯基碘化镁的Kharash型Grignard交叉偶联反应替代合成的。光谱研究表明，这些合成的八联苯显示出非常有特征的红外、紫外和核磁共振光谱。同时对八联苯最长波长吸收带的实验性Huckel分子轨道计算也进行了研究，除了两种化合物外，计算得到的波长与观测值相当吻合。

  DOI：

  10.1248/cpb.29.344
• 作为产物：
  描述：

  2-碘联苯 在 铁粉 、 铜 作用下， 以 苯 为溶剂， 反应 1.0h， 生成 4,4'''-diamino-o-quaterphenyl
  参考文献：
  名称：

  Syntheses and physical properties of several octiphenyls containing mixed linkages.

  摘要：

  通过碘四联苯的Ullmann同系偶联反应合成了8个新型线性八联苯，包含2种或3种连接方式。其中5个化合物是通过双(乙酰丙酮)镍(II)催化的二碘四联苯和联苯基溴化镁或三联苯基碘化镁的Kharash型Grignard交叉偶联反应替代合成的。光谱研究表明，这些合成的八联苯显示出非常有特征的红外、紫外和核磁共振光谱。同时对八联苯最长波长吸收带的实验性Huckel分子轨道计算也进行了研究，除了两种化合物外，计算得到的波长与观测值相当吻合。

  DOI：

  10.1248/cpb.29.344

文献信息

• THE SYNTHESIS OF 2,2′-DIPHENYLBENZIDINE
  作者：Shin-ichi Sako

  DOI：10.1246/bcsj.10.593

  日期：1935.12
• OZASA SHIGERU; FUJIOKA YASUHIRO; TSUKADA MACHIYO; IBUKI EIICHI, CHEM. AND PHARM. BULL., 1981, 29, NO 2, 344-355
  作者：OZASA SHIGERU、 FUJIOKA YASUHIRO、 TSUKADA MACHIYO、 IBUKI EIICHI

  DOI：——

  日期：——
• [EN] PROCESS FOR MAKING BENZOXAZINES<br/>[FR] PROCÉDÉ DE FABRICATION DE BENZOXAZINES
  申请人：CYTEC IND INC

  公开号：WO2016069358A1

  公开（公告）日：2016-05-06

  A synthesis process for making a benzoxazine compound containing at least one benzoxazine unit from aromatic amine containing at least one primary amino group, at least one phenolic compound with at least one ortho-hydrogen, and alkyl formcel. In one embodiment, the aromatic amine is reacted with alkyl formcel to generate an alkoxymethyl intermediate compound. Subsequently, the intermediate compound is reacted with a phenol to generate the benzoxazine compound. In another embodiment, the benzoxazine compound is formed by reacting aromatic amine with alkyl formcel and phenol in one reaction step. Also disclosed is a method for isolating the alkoxymethyl compound formed by reacting aromatic amine with alkyl formcel. The isolated alkoxymethyl compound is useful as a reactant in a subsequent reaction.
• Syntheses and physical properties of several octiphenyls containing mixed linkages.
  作者：SHIGERU OZASA、YASUHIRO FUJIOKA、MACHIYO TSUKADA、EIICHI IBUKI

  DOI：10.1248/cpb.29.344

  日期：——

  Eight new linear octiphenyls containing two or three kinds of linkage were synthesized by the Ullmann homo-coupling reaction of iodoquaterphenyl. Among them, five compounds were alternatively synthesized by the Kharash-type Grignard cross-coupling of biphenylylmagnesium bromide and diiodoquaterphenyl or of terphenylylmagnesium iodide and diiodoquaterphenyl in the presence of bis (acetylacetonato) nickel (II). Spectral studies proved that the octiphenyls thus prepared displayed highly characteristic infrared, ultraviolet, and nuclear magnetic resonance spectra. Empirical Huckel molecular orbital calculations of the longest wavelength absorption bands of the octiphenyls were also performed. The calculated and observed wavelengths were in rather good agreement, except for the cases of two compounds.

  通过碘四联苯的Ullmann同系偶联反应合成了8个新型线性八联苯，包含2种或3种连接方式。其中5个化合物是通过双(乙酰丙酮)镍(II)催化的二碘四联苯和联苯基溴化镁或三联苯基碘化镁的Kharash型Grignard交叉偶联反应替代合成的。光谱研究表明，这些合成的八联苯显示出非常有特征的红外、紫外和核磁共振光谱。同时对八联苯最长波长吸收带的实验性Huckel分子轨道计算也进行了研究，除了两种化合物外，计算得到的波长与观测值相当吻合。