2-[(吡啶-2-基甲基氨基)甲基]苯甲酸 | 658706-44-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-[(吡啶-2-基甲基氨基)甲基]苯甲酸
• 英文名称: N-(2-methylpyridine)-2-aminomethyl benzoic acid
• 英文别名: 2-[(pyridin-2-ylmethylazaniumyl)methyl]benzoate
• CAS: 658706-44-6
• 化学式: C₁₄H₁₄N₂O₂
• 分子量: 242.277
• InChiKey: WUZJJLRDZDXSOZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  62.2
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  manganese(II) perchlorate hexahydrate 、 2-[(吡啶-2-基甲基氨基)甲基]苯甲酸 在 NaOH 作用下， 以 乙腈 为溶剂， 以0%的产率得到bis (N-(2-methylpyridine)-2-aminomethylbenzoate) manganese(II)
  参考文献：
  名称：

  Synthesis, structural characterization and redox properties of copper(II) and manganese(II) complexes containing tridentate (N-(2-methylpyridine)-2-aminomethyl benzoate) ligand

  摘要：

  Two new complexes, [Cu(mamba)(2)] and [Mn(mamba)(2)] (mamba(-), N-(2-methylpyridine)-2-aminomethyl benzoate) were synthesized and characterized by X-ray crystallography. Whereas the [Cu(mamba)(2)] complex crystallizes in a monoclinic P2(1)/c space group, the [Mn(mamba)(2)] complex crystallizes in a triclinic P (l) over bar space group. The nature of the metal ion greatly influences the lattices and the molecular structures of the compounds. In the crystal lattice of the copper complex are four cocrystallized methanol solvent, which are all involved in building six strong H-bonds with the complex. However, the lattice for the manganese complex contain only one cocrystallized methanol, along with one NaClO4, that is also involved in making one H-bond with the [Mn(mamba)(2)] unit. Nevertheless, the sodium ion is coordinated to the ClO4, the methanol and two [Mn(mamba)(2)] to form a stable extended chain metal complex. Electrochemical studies indicated that both complexes undergo quasi reversible one electron reduction in acetonitrile. (C) 2003 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2003.10.025

文献信息

• Hexacoordinated cobalt(II) and nickel(II) complexes of a novel mixed ligand, N-(2-methylpyridine)-2-aminomethyl benzoic acid: structures, spectroscopic characterizations and redox studies
  作者：Xiaobao Li、Ghezai T Musie、Douglas R Powell

  DOI：10.1016/s0020-1693(03)00339-6

  日期：2003.11

  Two new metal complexes, [Co(Mamba)(2)] and [Ni(Mamba)(2)], have been prepared by the treatment of the tridentate ligand N-(2-methylpyridine)-2-aminomethyl benzoic acid (HMamba) with the respective metal salts (CO(ClO4)(2) and Ni(C2H3O2)(2)) in the presence of sodium hydroxide. The ligand was synthesized by reduction of the Schiff base which was obtained by condensation of 2-carboxybenzaldehyde with 2-(aminomethyl)pyridine, The complexes have been characterized using single crystal X-ray diffraction and other spectroscopic techniques. The structures of the complexes are octahedral with each metal center chelated to two ligands through the amine nitrogen atom, the pyridine nitrogen atom and benzoic acid oxygen atom of each Mamba(-). In solid state, an extended networks of H-bonding between cocrystallized solvent molecules and the metal complexes have been observed. Electrochemical studies of the complexes revealed the presence of metal-based one electron quasi-reversible reduction in acetonitrile. (C) 2003 Elsevier B.V. All rights reserved.
• Synthesis, structural characterization and redox properties of copper(II) and manganese(II) complexes containing tridentate (N-(2-methylpyridine)-2-aminomethyl benzoate) ligand
  作者：Ghezai T Musie、Xiaobao Li、Douglas R Powell

  DOI：10.1016/j.ica.2003.10.025

  日期：2004.3

  Two new complexes, [Cu(mamba)(2)] and [Mn(mamba)(2)] (mamba(-), N-(2-methylpyridine)-2-aminomethyl benzoate) were synthesized and characterized by X-ray crystallography. Whereas the [Cu(mamba)(2)] complex crystallizes in a monoclinic P2(1)/c space group, the [Mn(mamba)(2)] complex crystallizes in a triclinic P (l) over bar space group. The nature of the metal ion greatly influences the lattices and the molecular structures of the compounds. In the crystal lattice of the copper complex are four cocrystallized methanol solvent, which are all involved in building six strong H-bonds with the complex. However, the lattice for the manganese complex contain only one cocrystallized methanol, along with one NaClO4, that is also involved in making one H-bond with the [Mn(mamba)(2)] unit. Nevertheless, the sodium ion is coordinated to the ClO4, the methanol and two [Mn(mamba)(2)] to form a stable extended chain metal complex. Electrochemical studies indicated that both complexes undergo quasi reversible one electron reduction in acetonitrile. (C) 2003 Elsevier B.V. All rights reserved.