3-(1-oxo-1H-2,3-dihydroisoindol-2-yl)benzoic acid | 4770-70-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 3-(1-oxo-1H-2,3-dihydroisoindol-2-yl)benzoic acid
• 英文别名: 2-(3-carboxyphenyl)isoindolin-1-one；3-(1-oxoisoindol-2-yl)benzoic acid；2-(m-Carboxy-phenyl)-phthalimidin；mHpba；3-(1-oxo-1,3-dihydro-isoindol-2-yl)-benzoic acid；3-(1-Oxo-1,3-dihydro-2H-isoindol-2-yl)benzoic acid；3-(3-oxo-1H-isoindol-2-yl)benzoic acid
• CAS: 4770-70-1
• 化学式: C₁₅H₁₁NO₃
• 分子量: 253.257
• InChiKey: RLIXOQAKBDGAOW-UHFFFAOYSA-N

物化性质

• 沸点：
  515.3±50.0 °C(Predicted)
• 密度：
  1.385±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  57.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-硝基苯甲酸甲酯 在 铁粉 、 氯化铵 、 三乙胺 、 sodium hydroxide 作用下， 以 四氢呋喃 、 乙醇 、 水 为溶剂， 反应 5.0h， 生成 3-(1-oxo-1H-2,3-dihydroisoindol-2-yl)benzoic acid
  参考文献：
  名称：

  一类含多氟烷基异吲哚啉酮苯甲酰胺类衍生物、其制备方法及应用

  摘要：

  本发明提供了一类含多氟烷基异吲哚啉酮苯甲酰胺类衍生物，具有以下通式A‑1：取代基见说明书。本发明提供的含多氟烷基异吲哚啉酮苯甲酰胺类衍生物适合用于农用杀虫。

  公开号：

  CN112778192B

文献信息

• Synthesis of phthalimides, isoindolin-1-ones and isoindolines bearing aminobenzoic acids as a new fluorescent compounds
  作者：Melchor Solis-Santos、Mario Ordóñez、Adrián Ochoa-Terán、Rodrigo Morales-Cueto、Victoria Labastida-Galván

  DOI：10.1016/j.jphotochem.2021.113185

  日期：2021.5

  properties of nine new compounds based on phthalimides, isoindolin-1-ones and isoindolines bearing aminobenzoic acids (2-aminobenzoic acid, 3-aminobenzoic acid and 4-aminobenzoic acid), which were obtained under mild reaction conditions. The photophysical properties of all the compounds were studied by electronic absorption and fluorescence spectroscopy in methanol solutions. All compounds exhibited fluorescence

  为了研究九种基于邻苯二甲酰亚胺，异吲哚啉-1-酮和带有氨基苯甲酸（2-氨基苯甲酸，3-氨基苯甲酸和4-氨基苯甲酸）的异吲哚啉的新化合物的荧光性质，使用了实验方法和理论方法。在温和的反应条件下获得。通过电子吸收和荧光光谱在甲醇溶液中研究了所有化合物的光物理性质。所有化合物均显示出荧光发射和高量子产率。另外，发现这些供体-受体系统中的分子内电荷显着取决于羧酸位置的吸电子取代基。
• 2-, 3-, and 4-(1-Oxo-1H-2,3-dihydroisoindol-2-yl)benzoic acids and their corresponding organotin carboxylates: Synthesis, characterization, fluorescent, and biological activities
  作者：Shuang-Lian Cai、Yong Chen、Wen-Xia Sun、Hui Li、Yun Chen、Shi-Shan Yuan

  DOI：10.1016/j.bmcl.2010.08.034

  日期：2010.10

  Three novel organotin complexes with general formula Sn(OH)(bz)(2)L (bz = benzyl, HL = 2-, 3-, or 4-(1-oxo-1H-2,3-dihydroisoindol-2-yl)benzoic acid) and one of their ligands were prepared and characterized. In vitro antifungal and antibacterial activities of these complexes and ligands were investigated with the representative strains of Candida albicans, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. Their fluorescence properties have also been discussed. (C) 2010 Elsevier Ltd. All rights reserved.
• MOFs Modified Paper-Based Materials: Preparation and Application to EtOH Fluorescence Response
  作者：Qiang Yang Qiang Yang、Meiyun Zhang Meiyun Zhang、Wei Gong Wei Gong、Xiaowei Cui Xiaowei Cui、Chunsheng Zhou Chunsheng Zhou

  DOI：10.52568/001032/jcsp/44.03.2022

  日期：——

  Based on the solvothermal method, two new MOFs with 3-(1-Oxo-1H-2,3-dihydroisoindol-2-yl)benzoic acid as the organic ligand, Zn-HBPA and Zn-bpy-HBPA were synthesized. The structure of MOFs was characterized by 1H-NMR, XRD, FT-IR and SEM. A series of modified cellulose paper-based functional materials with different spraying times were prepared by flame spraying method, and the fluorescence property of MOFs modified cellulose paper to EtOH small molecules was investigated by fluorescence spectrometer. The results of FT-IR and SEM showed that the flame spraying method could effectively improve the retention rate of MOFs on cellulose paper materials. The PL characterization results displayed that Zn-HBPA@PFP exhibited a decrease in fluorescence after UV irradiation, while Zn-bpy-HBPA@PFP demenstrated an increase in fluorescence at λ=338 nm. The above results indicated that Zn-bpy-HBPA@PFP had an excellent response ability to EtOH small molecules, and when Cycle=7 times, Zn-bpy-HBPA@PFP had the best fluorescence enhancement effect.
• 一类含多氟烷基异吲哚啉酮苯甲酰胺类衍生物、其制备方法及应用
  申请人：浙江省化工研究院有限公司

  公开号：CN112778192B

  公开（公告）日：2022-12-02

  本发明提供了一类含多氟烷基异吲哚啉酮苯甲酰胺类衍生物，具有以下通式A‑1：取代基见说明书。本发明提供的含多氟烷基异吲哚啉酮苯甲酰胺类衍生物适合用于农用杀虫。