(Z)-1-(4-hydroxyphenyl)propene | 85960-81-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (Z)-1-(4-hydroxyphenyl)propene
• 英文别名: (Z)-4-(1-Propenyl)phenol；4-[(Z)-prop-1-enyl]phenol
• CAS: 85960-81-2
• 化学式: C₉H₁₀O
• 分子量: 134.178
• InChiKey: UMFCIIBZHQXRCJ-IHWYPQMZSA-N

物化性质

• LogP：
  2.69
• 保留指数：
  1279.6

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (Z)-1-(4-hydroxyphenyl)propene 在 磷酸 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 48.0h， 生成 (E)-1-(4-hydroxyphenyl)propene
  参考文献：
  名称：

  Chiral Phosphoric Acid Catalyzed Inverse-Electron-Demand Aza-Diels–Alder Reaction of Isoeugenol Derivatives

  摘要：

  Highly enantio- and diastereoselective three-component inverse electron-demand aza-Diels-Alder reaction of aldehydes, anilines, and isoeugenol derivatives catalyzed by a chiral phosphoric acid catalyst are reported. A wide variety of 2,3,4-trisubstituted tetrahydroquinolines containing an aryl group at the 4-position were obtained in a one-pot process with good to high yields and excellent stereoselectivities (>95:5 dr and up to >99% ee).

  DOI：

  10.1021/ol301251h
• 作为产物：
  描述：

  乙基三苯基溴化膦 、 对羟基苯甲醛 在 水 、 potassium carbonate 作用下， 以 1,4-二氧六环 为溶剂， 反应 1.5h， 生成 (E)-1-(4-hydroxyphenyl)propene 、 (Z)-1-(4-hydroxyphenyl)propene
  参考文献：
  名称：

  异质固相-液相反应：醛类的转化指导

  摘要：

  在质子和非质子介质中，在碳酸钾的存在下，使用固-液相转移，可以直接获得新的烯基酚，而无需保护酚基不受酚醛与各种salts盐之间的缩合反应的影响。

  DOI：

  10.1016/s0040-4039(00)81363-5

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• [EN] LATENT ACIDS AND THEIR USE<br/>[FR] ACIDES LATENTS ET LEUR UTILISATION
  申请人：BASF SE

  公开号：WO2016124493A1

  公开（公告）日：2016-08-11

  Compounds of the formula (I) and (IA) wherein X is -O(CO)-; R1 is C1-C12haloalkyl or C6-C10haloaryl; R2 is located in position 7 of the coumarinyl ring and is OR8; R2a, R2b and R2C independently of each other are hydrogen; R3 is C1-C8haloalkyl or C1-C8haloalkyl; R4 is hydrogen; and R8 is C1-C6alkyI; are suitable as photosensitive acid donors in the preparation of photoresist compositions such as used for example in the preparation of spacers, insulating layers, interlayer dielectric films, insulation layers, planarization layers, protecting layers, overcoat layers, banks for electroluminescence displays and liquid crystal displays (LCD).

  化合物的化学式（I）和（IA），其中X为-O(CO)-；R1为C1-C12卤代烷基或C6-C10卤代芳基；R2位于香豆素环的第7位，为OR8；R2a、R2b和R2C彼此独立地为氢；R3为C1-C8卤代烷基或C1-C8卤代烷基；R4为氢；R8为C1-C6烷基，适用于作为感光酸给体，用于制备光刻胶组合物，例如用于制备间隔层、绝缘层、层间介质膜、绝缘层、平坦化层、保护层、覆盖层、电致发光显示器和液晶显示器（LCD）的制备。
• Alkylsulfonyloximes for high-resolution i-line photoresists of high sensitivity
  申请人：——

  公开号：US20040013974A1

  公开（公告）日：2004-01-22

  The invention describes the use of oxime alkyl sulfonate compounds of formula 1 1 R 0 is either an R 1 —X group or R 2 ; X is a direct bond, an oxygen atom or a sulfur atom; R 1 is hydrogen, C 1 -C 4 alkyl or a phenyl group which is unsubstituted or substituted by a substituent selected from the group consisting of chloro, bromo, C 1 -C 4 alkyl and C 1 -C 4 -alkyloxy; R 2 is hydrogen or C 1 -C 4 alkyl; and R 3 is straight-chain or branched C 1 -C 12 alkyl which is unsubstituted or substituted by one or more than one halogen atom; as photosensitive add generator in a chemically amplified photoresist which is developable in alkaline medium and which is sensitive to radiation at a wavelength of 340 to 390 nanometers and correspondingly composed positive and negative photoresists for the above-mentioned wavelength range.

  该发明描述了氧肟烷磺酸酯化合物的使用，其化学式为11R0，其中R0是R1—X基团或R2；X是一个直接键，一个氧原子或一个硫原子；R1是氢，C1-C4烷基或苯基，未取代或取代，取代基选择自氯、溴、C1-C4烷基和C1-C4-烷氧基组成的组；R2是氢或C1-C4烷基；R3是直链或支链的C1-C12烷基，未取代或取代，取代一个或多个卤素原子；作为化学增感光阻剂中的光敏添加剂，该增感光阻剂可在碱性介质中显影，对波长为340至390纳米的辐射敏感，相应地组成了上述波长范围内的正负光刻胶。
• NOVEL CHEMOTHERAPEUTIC AGENTS AGAINST INFLAMMATION AND CANCER
  申请人：Bose Julie Saha

  公开号：US20100168228A1

  公开（公告）日：2010-07-01

  Novel compounds, their methods of preparation and use in therapies related to cancer and inflammation are provided. Compounds comprise esters of cinnamic acid, vanillic acid and 4-hydroxy cinnamic acid and derivatives and salts thereof. Compounds with novel benzofuran lignan structure as a potent antimitotic agent and inducer of apoptosis are provided. Formulations and methods for treatment of diseases mediated by NF-kappaB are also provided.

  提供了新型化合物、其制备方法以及在与癌症和炎症相关的治疗中的用途。这些化合物包括肉桂酸酯、香草酸酯和4-羟基肉桂酸酯及其衍生物和盐。提供了具有新型苯并呋喃木脂素结构的化合物，作为一种强效抗有丝分裂剂和诱导凋亡剂。还提供了用于治疗NF-kappaB介导的疾病的配方和方法。
• Oximesulfonic acid esters and the use thereof as latent sulfonic acids
  申请人：——

  公开号：US20010037037A1

  公开（公告）日：2001-11-01

  The invention relates to the use of oximesulfonic acid esters of formula I 1 wherein m is 0 or 1 and x is 1 or 2; R 1 is, for example, substituted phenyl, R 2 has, for example, one of the meanings of R 1 or is unsubstituted phenyl, C 1 -C 6 alkanoyl, unsubstituted or substituted benzoyl, C 2 -C 6 alkoxycarbonyl or phenoxycarbonyl; or R 1 and R 2 , if necessary together with the CO group, form a ring, R 3 , when x is 1, is, for example, C 1 -C 18 alkyl, phenyl or phenanthryl, the radicals phenyl and phenanthryl being unsubstituted or substituted, or R 3 , when x is 2, is, for example, C 2 -C 12 alkylene, phenylene or oxydiphenylene, the radicals phenylene and oxydiphenylene being unsubstituted or substituted, as latent acid donors, especially at wavelengths over 390 nm, and to the use of the compounds in the production of photoresists.

  该发明涉及使用式I1的羟胺磺酸酯，其中m为0或1，x为1或2；R1为例如取代苯基，R2为例如具有R1的一种含义或为未取代苯基、C1-C6烷酰基、未取代或取代苯甲酰基、C2-C6烷氧羰基或苯氧羰基；或者如果必要，R1和R2连同CO基团一起形成环，当x为1时，R3为例如C1-C18烷基、苯基或苯并芘基，其中苯基和苯并芘基未取代或取代，或当x为2时，R3为例如C2-C12烷基、苯基或氧二苯基，其中苯基和氧二苯基未取代或取代，作为潜在酸供体，特别是在波长超过390纳米时，以及在光阻剂的生产中使用这些化合物。