Crystallizable polylactone copolymers prepared from mono- and di-functional polymerization initiators
申请人:ETHICON, INC.
公开号:EP1374921A1
公开(公告)日:2004-01-02
The present invention is directed to absorbable polylactone copolymers prepared in part from about 2 to about 80 mole percent glycolide, utilizing a combination of a monofunctional polymerization initiator and a di-functional polymerization initiator, to achieve rates of crystallization of the copolymer of at least about 2 times faster than the rate of crystallization of a copolymer made by a similar process utilizing either the mono-functional or the di-functional polymerization initiator alone. Medical devices containing such copolymers are also disclosed.
本发明的目的是利用单官能团聚合引发剂和双官能团聚合引发剂的组合,制备部分由约 2 至约 80 摩尔百分数的羟基乙内酯组成的可吸收的聚乳酸共聚物,使共聚物的结晶速率比单独使用单官能团或双官能团聚合引发剂的类似工艺制作的共聚物的结晶速率至少快约 2 倍。此外,还公开了含有这种共聚物的医疗器械。