heptanoyl bromide | 18255-47-5

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: heptanoyl bromide
• CAS: 18255-47-5
• 化学式: C₇H₁₃BrO
• 分子量: 193.084
• InChiKey: VILVQWOKZHEUOO-UHFFFAOYSA-N

物化性质

• 沸点：
  135 °C(Press: 45 Torr)
• 密度：
  1.250±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  heptanoyl bromide 在 四氯化碳 、 水 作用下， 生成 正戊基丙二酸
  参考文献：
  名称：

  Treibs; Orttmann, Chemische Berichte, 1958, vol. 91, p. 297,300

  摘要：

  DOI：
• 作为产物：
  描述：

  庚酸 在 三溴化磷 作用下， 生成 heptanoyl bromide
  参考文献：
  名称：

  Kirrmann, Annales de Chimie (Cachan, France), 1929, vol. <10>11, p. 232,271

  摘要：

  DOI：

文献信息

• METHOD FOR PRODUCING CYCLIC SULFONIC ACID ESTER AND INTERMEDIATE THEREOF
  申请人：Kuramoto Ayako

  公开号：US20120130089A1

  公开（公告）日：2012-05-24

  The present invention is directed to provide an efficient production method which is capable of not only obtaining a cyclic sulfonic acid ester (sultone) at low cost and in high yield, but also the sulfonic acid ester (sultone) stably even in a commercial scale. The present invention relates to a method for producing hydroxysultone comprising a first step where a diol having a specified structure and a thionyl halide are reacted to obtain a cyclic sulfite having a specified structure, and a second step where the cyclic sulfite is reacted with water or/and alcohol; a method for producing an unsaturated sultone having a specified structure comprising a third step where a hydroxylsultone having a specified structure is reacted with an acid halide or an acid anhydride to obtain an intermediate, subsequently the intermediate is treated with a base; as well as a cyclic sulfite having a specified structure.

  本发明旨在提供一种高效的生产方法，该方法不仅能够以低成本和高产率获得环状磺酸酯（磺酮），而且能够在商业规模下稳定地生产磺酸酯（磺酮）。本发明涉及一种生产羟基磺酮的方法，包括第一步，其中将具有特定结构的二元醇和硫酰卤反应，以获得具有特定结构的环状亚磺酸酯，以及第二步，其中将环状亚磺酸酯与水或/和醇反应；一种生产具有特定结构的不饱和磺酮的方法，包括第三步，其中将具有特定结构的羟基磺酮与酸卤或酸酐反应，以获得中间体，随后用碱处理中间体；以及具有特定结构的环状亚磺酸酯。
• SUBSTITUTED 6-H-1,3,4-THIADIAZINE-2-AMINES, THE USE THEREOF AS AN AESTHETISING, CARDIOVASCULAR AND HYPOMETABOLIC AGENTS, AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0877024A1

  公开（公告）日：1998-11-11

  Substituted 6H-1,3,4-thiadiazin-2-amines of the following general formula: wherein Ar is phenyl optionally substituted with one or more chloro, bromo atoms, C1-C4 alkoxy or C1-C4 alkyl groups; and represents a morpholino, thiomorpholino, piperidino, pyrrolidino, or hexamethylenimino moieties, the pharmaceutically acceptable salts thereof and the use of them as anaesthetic, cardiovascular and hypometabolic agents and pharmaceutical compositions containing them.

  通式如下的被取代的 6H-1,3,4-噻二嗪-2-胺： 其中 Ar 是任选被一个或多个氯原子、溴原子、C1-C4 烷氧基或 C1-C4 烷基取代的苯基；以及 代表吗啉基、硫代吗啉基、哌啶基、吡咯烷基或六亚甲基亚氨 基的分子、其药学上可接受的盐类以及用作麻醉剂、心血管药剂和低代谢药剂和含 有它们的药物组合物。
• 1,3-propanesultone derivative useful in the preparation of a 1,3-propenesultone derivative
  申请人：Wako Pure Chemical Industries, Ltd.

  公开号：EP2757102A1

  公开（公告）日：2014-07-23

  The present invention is directed to provide an efficient production method which is capable of not only obtaining a cyclic sulfonic acid ester (sultone) at low cost and in high yield, but also the sulfonic acid ester (sultone) stably even in a commercial scale. The present invention relates to a method for producing hydroxysultone comprising a first step where a diol having a specified structure and a thionyl halide are reacted to obtain a cyclic sulfite having a specified structure, and a second step where the cyclic sulfite is reacted with water or/and alcohol; a method for producing an unsaturated sultone having a specified structure comprising a third step where a hydroxylsultone having a specified structure is reacted with an acid halide or an acid anhydride to obtain an intermediate, subsequently the intermediate is treated with a base; as well as a cyclic sulfite having a specified structure.

  本发明旨在提供一种高效的生产方法，该方法不仅能够低成本、高产率地获得环状磺酸酯（磺内酯），而且即使在商业规模上也能稳定地获得磺酸酯（磺内酯）。本发明涉及一种生产羟基磺酸内酯的方法，包括第一步：具有特定结构的二元醇与亚 硫酰卤反应，得到具有特定结构的环状亚硫酸盐；第二步：环状亚硫酸盐与水或/和醇反应；一种生产具有特定结构的不饱和舒尔酮的方法，包括第三步：具有特定结构的羟基舒尔酮与酸卤化物或酸酐反应，得到中间体，然后用碱处理中间体；以及具有特定结构的环状亚硫酸盐。
• Radical mediated oxidations in organic chemistry. 3. An efficient and versatile transformation of aldehydes into amides ¥.
  作者：István E. Markó、Abdelaziz Mekhalfia

  DOI：10.1016/s0040-4039(00)97289-7

  日期：1990.1
• Metacyclophanes and related compounds. 24. Preparation and reaction of trimethyl[2.2.2]- and tetramethyl[2.2.2.2]metacyclophane
  作者：Masashi Tashiro、Tetsuya Watanabe、Akihiko Tsuge、Tsuyoshi Sawada、Shuntaro Mataka

  DOI：10.1021/jo00272a034

  日期：1989.5