3-methoxy-caproic acid methyl ester | 54905-29-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3-methoxy-caproic acid methyl ester
• 英文别名: 3-Methoxy-hexansaeure-methylester；Methyl 3-methoxy-hexanoate；Methyl-3-methoxyhexanoat；Methyl 3-methoxyhexanoate
• CAS: 54905-29-2
• 化学式: C₈H₁₆O₃
• 分子量: 160.213
• InChiKey: FGRRNMYHWQHHRN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-methoxy-caproic acid methyl ester 在 sodium hydroxide 作用下， 以 甲醇 为溶剂， 生成 3-甲氧基己酸
  参考文献：
  名称：

  Micromide and Guamamide:  Cytotoxic Alkaloids from a Species of the Marine Cyanobacterium Symploca

  摘要：

  Two new cytotoxins have been isolated from a species of marine cyanobacterium belonging to the genus Symploca that was collected in Guam. These new compounds, micromide (1) and guamamide (2), were accompanied by the known lipopeptides apramides A (3), B (4), and G (5). The planar structures of both alkaloids were elucidated by standard 2D NMR techniques, and the configurations of the amino acid-derived units in 1 were determined by chiral HPLC. The stereochemistry of the beta-methoxyhexanoic acid in 1 was determined by derivatization with methyl D-mandelate, after acid hydrolysis, and comparison with synthetic standards.

  DOI：

  10.1021/np030215x
• 作为产物：
  描述：

  3-羟基己酸甲酯 、 硫酸二甲酯 在 氢氧化钾 、 三乙胺 作用下， 以 Petroleum ether 为溶剂， 反应 5.0h， 生成 3-methoxy-caproic acid methyl ester
  参考文献：
  名称：

  Micromide and Guamamide:  Cytotoxic Alkaloids from a Species of the Marine Cyanobacterium Symploca

  摘要：

  Two new cytotoxins have been isolated from a species of marine cyanobacterium belonging to the genus Symploca that was collected in Guam. These new compounds, micromide (1) and guamamide (2), were accompanied by the known lipopeptides apramides A (3), B (4), and G (5). The planar structures of both alkaloids were elucidated by standard 2D NMR techniques, and the configurations of the amino acid-derived units in 1 were determined by chiral HPLC. The stereochemistry of the beta-methoxyhexanoic acid in 1 was determined by derivatization with methyl D-mandelate, after acid hydrolysis, and comparison with synthetic standards.

  DOI：

  10.1021/np030215x

文献信息

• MULTILAYER COATING FILM FORMING METHOD
  申请人：Nippon Paint Automotive Coatings Co., Ltd.

  公开号：EP3827904A1

  公开（公告）日：2021-06-02

  The present invention aims to provide a method for forming a multilayer coating film having good coating film smoothness. A method for forming a multilayer coating film, comprising a first aqueous coating composition application step of applying a first aqueous coating composition (A) to form an uncured first aqueous coating film; a second aqueous coating composition application step of applying a second aqueous coating composition (B) onto the uncured first aqueous coating film to form an uncured second aqueous coating film; a clear coating step of applying a clear coating composition (C) onto the uncured second aqueous coating film to form an uncured clear coating film; and a curing step of heat-curing at once these coating films to form a multilayer coating film, wherein the first aqueous coating composition (A) contains a water-dispersible polyurethane resin (a1) and a viscosity modifier (a2), and the second aqueous coating composition (B) contains water and an organic solvent as diluent components besides solid matters in a state of dilution to a coating viscosity.

  本发明旨在提供一种形成具有良好涂膜平滑性的多层涂膜的方法。一种形成多层涂膜的方法，包括第一水性涂膜组合物涂敷步骤，在未固化的第一水性涂膜上涂敷第一水性涂膜组合物（A），形成未固化的第一水性涂膜；第二水性涂膜组合物涂敷步骤，在未固化的第一水性涂膜上涂敷第二水性涂膜组合物（B），形成未固化的第二水性涂膜；透明涂层步骤：在未固化的第二水性涂膜上涂布透明涂层组合物 (C)，形成未固化的透明涂膜；以及将这些涂膜同时加热固化以形成多层涂膜的固化步骤，其中第一水性涂料组合物 (A) 包含水分散性聚氨酯树脂 (a1) 和粘度调节剂 (a2)，而第二水性涂料组合物 (B) 除了稀释至涂料粘度的固体物质外，还包含作为稀释成分的水和有机溶剂。
• Method for forming multilayer coating film
  申请人：NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD.

  公开号：US11247231B2

  公开（公告）日：2022-02-15

  The present invention aims to provide a method for forming a multilayer coating film having good coating film smoothness. A method for forming a multilayer coating film, comprising a first aqueous coating composition application step of applying a first aqueous coating composition (A) to form an uncured first aqueous coating film; a second aqueous coating composition application step of applying a second aqueous coating composition (B) onto the uncured first aqueous coating film to form an uncured second aqueous coating film; a clear coating step of applying a clear coating composition (C) onto the uncured second aqueous coating film to form an uncured clear coating film; and a curing step of heat-curing at once these coating films to form a multilayer coating film, wherein the first aqueous coating composition (A) contains a water-dispersible polyurethane resin (a1) and a viscosity modifier (a2), and the second aqueous coating composition (B) contains water and an organic solvent as diluent components besides solid matters in a state of dilution to a coating viscosity.

  本发明旨在提供一种形成具有良好涂膜平滑性的多层涂膜的方法。一种形成多层涂膜的方法，包括第一水性涂膜组合物涂敷步骤，在未固化的第一水性涂膜上涂敷第一水性涂膜组合物（A），形成未固化的第一水性涂膜；第二水性涂膜组合物涂敷步骤，在未固化的第一水性涂膜上涂敷第二水性涂膜组合物（B），形成未固化的第二水性涂膜；透明涂层步骤：在未固化的第二水性涂膜上涂布透明涂层组合物 (C)，形成未固化的透明涂膜；以及将这些涂膜同时加热固化以形成多层涂膜的固化步骤，其中第一水性涂料组合物 (A) 包含水分散性聚氨酯树脂 (a1) 和粘度调节剂 (a2)，而第二水性涂料组合物 (B) 除了稀释至涂料粘度的固体物质外，还包含作为稀释成分的水和有机溶剂。
• The palladium(II) catalyzed olefin carbonylation reaction. Mechanisms and synthetic utility
  作者：D. E. James、J. K. Stille

  DOI：10.1021/ja00423a028

  日期：1976.3
• METHOD FOR FORMING MULTILAYER COATING FILM
  申请人：NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD.

  公开号：US20210245198A1

  公开（公告）日：2021-08-12

  The present invention aims to provide a method for forming a multilayer coating film having good coating film smoothness. A method for forming a multilayer coating film, comprising a first aqueous coating composition application step of applying a first aqueous coating composition (A) to form an uncured first aqueous coating film; a second aqueous coating composition application step of applying a second aqueous coating composition (B) onto the uncured first aqueous coating film to form an uncured second aqueous coating film; a clear coating step of applying a clear coating composition (C) onto the uncured second aqueous coating film to form an uncured clear coating film; and a curing step of heat-curing at once these coating films to form a multilayer coating film, wherein the first aqueous coating composition (A) contains a water-dispersible polyurethane resin (a1) and a viscosity modifier (a2), and the second aqueous coating composition (B) contains water and an organic solvent as diluent components besides solid matters in a state of dilution to a coating viscosity.
• US6033826A
  申请人：——

  公开号：US6033826A

  公开（公告）日：2000-03-07