DL-2-aminoheptanamide | 53726-15-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: DL-2-aminoheptanamide
• 英文别名: 2-Aminoheptanamide
• CAS: 53726-15-1
• 化学式: C₇H₁₆N₂O
• 分子量: 144.217
• InChiKey: UMGJWCXKSKEXOF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  69.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] AMINO ARYL ACETAMIDES AND THEIR USE IN THE TREATMENT OF MALARIA<br/>[FR] AMINOARYLACÉTAMIDES ET LEUR UTILISATION DANS LE TRAITEMENT DU PALUDISME
  申请人：GLAXO GROUP LTD

  公开号：WO2011061277A1

  公开（公告）日：2011-05-26

  Amino phenyl acetamide compounds of Formula (I):and pharmaceutically acceptable salts thereof: wherein R1, R2, R3 and Ra are as defined in the description, use of such compounds in the chemotherapy of certain parasitic protozoal infections such as malaria, pharmaceutical compositions including such compounds and processes for the preparation of such compounds, are provided.

  化合物的氨基苯乙酰胺的化合物的分子式（I）及其药学上可接受的盐：其中R1、R2、R3和Ra如描述中所定义，这些化合物在化疗某些寄生原虫感染，如疟疾中的用途，包括这些化合物的制药组合物和制备这些化合物的方法。
• [EN] NOVEL DIAZEPINE COMPOUNDS AS LIGANDS OF THE MELANOCORTIN 1 AND/OR 4 RECEPTORS<br/>[FR] NOUVEAUX COMPOSES DE DIAZEPINE UTILISES COMME LIGANDS DES RECEPTEURS 1 ET/OU 4 DE LA MELANOCORTINE
  申请人：SMITHKLINE BEECHAM CORP

  公开号：WO2005118573A1

  公开（公告）日：2005-12-15

  There is provided novel diazepines that function as agonists at the melanocortin 4 receptor and as agonists at the melanocortin 1 receptor, pharmaceutical compositions containing them, methods for their use in treatment, and processes for their preparation.

  提供了一种新型的二氮杂环己烯类化合物，其在黑色素皮质素4受体上具有激动剂作用，并在黑色素皮质素1受体上也具有激动剂作用，包含它们的药物组合物，以及它们在治疗中的使用方法和制备过程。
• Novel Diazepine Compounds as Ligands of the Melanocortin 1 and/or 4 Receptors
  申请人：Szewczyk Ryszard Jerzy

  公开号：US20070270411A1

  公开（公告）日：2007-11-22

  There is provided novel diazepines that function as agonists at the melanocortin 4 receptor and as agonists at the melanocortin 1 receptor, pharmaceutical compositions containing them, methods for their use in treatment, and processes for their preparation.

  提供了一种新颖的二氮杂苯，它在黑色素皮质素4受体上作为激动剂，在黑色素皮质素1受体上作为激动剂，包含它们的药物组成物，用于治疗的方法以及它们的制备过程。
• Azetidinone derivatives
  申请人：AJINOMOTO CO., INC.

  公开号：EP0076621A2

  公开（公告）日：1983-04-13

  Azetidinone derivatives having the general formula: wherein Z is methylthio group or a methylsulphonyl group, X is a hydrogen atom, a halogen atom, an amino group, an alkylamino group or an acylamino group, and Y is either of the groups: wherein R is an alkyl group, an aralkyl group or a 2,2,2-trichloroethyl group, and M is a halogen atom or an alkali metal atom, are useful for inhibiting the activity of β-lactamase such as that produced by bacteria being treated with a penicillin or a cephalosporin.

  具有以下通式的氮杂环丁酮衍生物：其中 Z 是甲硫基或甲磺酰基，X 是氢原子、卤素原子、氨基、烷基氨基或酰氨基，Y 是以下任一基团：其中 R 是烷基、芳烷基或 2,2,2- 三氯乙基，M 是卤素原子或碱金属原子，可用于抑制β-内酰胺酶的活性，如用青霉素或头孢菌素处理细菌时产生的β-内酰胺酶的活性。
• Filtration membranes
  申请人：PALL CORPORATION

  公开号：EP0272842A2

  公开（公告）日：1988-06-29

  A porous polymeric medium having low protein affinity is provided comprising a porous polymeric substrate and a polymer coating having a low affinity for amide group-containing materials formed in situ at the surface of the porous polymeric substrate from a polymer having a plurality of hydroxyl groups and a cross-linking agent having functional groups which react with the hydroxyl groups.

  提供了一种具有低蛋白质亲和力的多孔聚合物介质，包括多孔聚合物基底和在多孔聚合物基底表面由具有多个羟基的聚合物和具有与羟基反应的官能团的交联剂就地形成的对含酰胺基材料具有低亲和力的聚合物涂层。