(E)-1-Butoxy-2-(4-cyanophenyl)ethylene | 127087-66-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-1-Butoxy-2-(4-cyanophenyl)ethylene
• 英文别名: 4-[(E)-2-butoxyethenyl]benzonitrile
• CAS: 127087-66-5
• 化学式: C₁₃H₁₅NO
• 分子量: 201.268
• InChiKey: XSIIBRXLDRAFIA-CSKARUKUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  33
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-(1-丁氧基乙烯基)-4-(三氟甲基)苯 、 (E)-1-Butoxy-2-(4-cyanophenyl)ethylene 以84%的产率得到
  参考文献：
  名称：

  Cabri Walter, Candiani Ilaria, Bedeschi Angelo, Senti Roberto, J. Org. Chem, 58 (1993) N 26, S 7421-7426

  摘要：

  DOI：
• 作为产物：
  描述：

  乙烯基正丁醚 、 三氟甲磺酸4-氰基苯基醚 、 醋酸钯 生成 (E)-1-Butoxy-2-(4-cyanophenyl)ethylene
  参考文献：
  名称：

  CABRI, WALTER;CANDIANI, MARIA;BEDESCHI, ANGELO, J. ORG. CHEM., 55,(1990) N1, C. 3654-3655

  摘要：

  DOI：

文献信息

• Palladium-Catalyzed Regioselective Arylation of an Electron-Rich Olefin by Aryl Halides in Ionic Liquids
  作者：Lijin Xu、Weiping Chen、James Ross、Jianliang Xiao

  DOI：10.1021/ol000362b

  日期：2001.1.1

  [figure: see text] Palladium-catalyzed arylation of the electron-rich olefin butyl vinyl ether has been accomplished in the ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF4]), using as the arylating agents aryl iodides and bromides instead of the commonly used, but commercially unavailable and expensive, aryl triflates. The reaction proceeds with high efficiency and remarkable

  [图：见正文]富电子的烯烃丁基乙烯基醚的钯催化芳基化已在离子液体1-丁基-3-甲基咪唑四氟硼酸酯（[bmim] [BF4]）中完成，使用芳基碘化物作为芳基化剂和溴化物代替了芳烃三氟甲磺酸芳烃，而不是常用但市售和昂贵的芳基三氟甲磺酸酯。该反应以高效率和显着的区域选择性进行，几乎完全导致被烯烃碳α上的各种芳基取代为丁基乙烯基醚的杂原子。
• A new efficient tetraphosphine/palladium catalyst for the Heck reaction of aryl halides with styrene or vinylether derivatives
  作者：Marie Feuerstein、Henri Doucet、Maurice Santelli

  DOI：10.1016/s0040-4039(02)00219-8

  日期：2002.3

  cis,cis,cis-1,2,3,4-Tetrakis(diphenylphosphinomethyl)cyclopentane/[PdCl(C3H5)]2 system efficiently catalyses the Heck reaction of aryl halides with styrene and vinylether derivatives. High turnover numbers can be obtained for the reaction of several aryl halides with styrene and styrene derivatives. Lower turnover numbers have been observed in the presence of vinylethers.

  顺式，顺式，顺式-1,2,3,4-四（二苯基膦甲基）环戊烷/ [PdCl（C 3 H 5）] 2体系有效地催化了芳基卤化物与苯乙烯和乙烯基醚衍生物的Heck反应。对于几种芳基卤化物与苯乙烯和苯乙烯衍生物的反应，可以获得高周转率。在乙烯基醚存在下，观察到较低的营业额。
• Ligand-controlled .alpha.-regioselectivity in palladium-catalyzed arylation of butyl vinyl ether
  作者：Walter Cabri、Ilaria Candiani、Angelo Bedeschi、Roberto Santi

  DOI：10.1021/jo00298a050

  日期：1990.5
• 1,10-Phenanthroline derivatives: a new ligand class in the Heck reaction. Mechanistic aspects
  作者：Walter Cabri、Ilaria Candiani、Angelo Bedeschi、Roberto Santi

  DOI：10.1021/jo00078a021

  日期：1993.12

  Mechanistic studies concerning the use of 1,10-phenanthroline derivatives as palladium ligands in the Heck reaction are described. The work is focused on the steering factors for the coordination of unsaturated systems onto palladium(0) and palladium(II) complexes.