2-benzylidenamino-butan-1-ol | 40355-37-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-benzylidenamino-butan-1-ol
• 英文别名: 2-(benzylideneamino)butan-1-ol
• CAS: 40355-37-1
• 化学式: C₁₁H₁₅NO
• 分子量: 177.246
• InChiKey: FQAGQRNEODORRX-UHFFFAOYSA-N

物化性质

• 沸点：
  105-113 °C(Press: 0.15 Torr)
• 密度：
  1.0192 g/cm3(Temp: 25 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  1.88
• 重原子数：
  13.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  32.59
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  2-benzylidenamino-butan-1-ol 在 溶剂黄146 、 三乙胺 作用下， 以 苯 为溶剂， 生成 5-ethyl-2-(2'-hydroxyethoxy)-3-phenyl-1,4,2λ⁵-oxazaphosphorinane 2-oxide
  参考文献：
  名称：

  摘要：

  DOI：

  10.1023/a:1013206003000
• 作为产物：
  描述：

  2-氨基-1-丁醇 、 苯甲醛 生成 2-benzylidenamino-butan-1-ol
  参考文献：
  名称：

  Reactions of Aminoalcohol—Aldehyde Anhydro Compounds

  摘要：

  DOI：

  10.1021/ja01120a046

文献信息

• A new synthetic route to chiral 3-aryl-5-ethyl-1,4,2-oxazaphosphorines
  作者：Kirill E. Metlushka、Dilyara N. Sadkova、Kristina A. Nikitina、Zilya R. Yamaleeva、Kamil A. Ivshin、Olga N. Kataeva、Vladimir A. Alfonsov

  DOI：10.1016/j.mencom.2018.11.004

  日期：2018.11

  Diastereoselective synthesis of racemic and enantiopure 3-aryl-5-ethyl-1,4,2-oxazaphosphorines, including those bearing phenolic hydroxyl groups in the exocyclic aromatic fragment, was implemented by the reaction of imines derived from (+/-)- and (R)-(-)-2-aminobutan-1-ol and (hydroxy)benzaldehydes with triethyl phosphite and trifluoroacetic acid, followed by the one-pot dealkylation of the intermediate esters.
• Membrane transport of dicarboxylic and α-hydroxy carboxylic acids induced by α-amino phosphonates
  作者：I. I. Stoikov、N. A. Fitseva、L. R. Akhmetzyanova、L. I. Gafioullina、I. S. Antipin、V. F. Zheltukhin、A. I. Devyaterikova、V. A. Al"fonsov、A. I. Konovalov

  DOI：10.1023/b:rucb.0000046257.44290.84

  日期：2004.7

  New alpha-amino phosphonates containing different alkyl and aryl substituents at the alpha-carbon atom were synthesized in high yields by the Kabachnik-Fields and Pudovik reactions. These compounds were studied as carriers of several alpha-hydroxy carboxylic and dicarboxylic acids through liquid impregnated membranes. These alpha-amino phosphonates studied are capable of molecular recognition of oxalic acid among structurally similar alpha-hydroxy carboxylic and dicarboxylic acids. The efficiency and selectivity of mass transfer of oxalic acid increase with an increase in the lipophilicity of the alpha-amino phosphonate.
• Reactions of Aminoalcohol—Aldehyde Anhydro Compounds
  作者：Eugene P. Goldberg、Harold R. Nace

  DOI：10.1021/ja01120a046

  日期：1953.12
• ——
  作者：M. N. Dimukhametov、E. V. Bayandina、E. Yu. Dabydova、V. A. Al'fonsov

  DOI：10.1023/a:1013206003000

  日期：——