N-[(Pyren-1-YL)methyl]pyridine-2-carboxamide | 680198-52-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 英文名称: N-[(Pyren-1-YL)methyl]pyridine-2-carboxamide
• 英文别名: N-(pyren-1-ylmethyl)pyridine-2-carboxamide
• CAS: 680198-52-1
• 化学式: C₂₃H₁₆N₂O
• 分子量: 336.393
• InChiKey: WOKXCXKSUYHOJP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  42
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-吡啶甲酰氯 、 1-芘甲胺 盐酸盐 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 4.0h， 以90%的产率得到N-[(Pyren-1-YL)methyl]pyridine-2-carboxamide
  参考文献：
  名称：

  Self-Association and Nitroaromatic-Induced Deaggregation of Pyrene Substituted Pyridine Amides

  摘要：

  The self-assembly features of the bis-pyrene methyl amide functionalized pyridine and benzene "tweezers" 1 and 2 were studied in organic solution and in the solid state. These systems were found to display remarkably different self-association features and optical properties, which was rationalized by control experiments using compounds bearing pyrenemethyl esters, alkyl groups, or a single pyrene substituent (3-6). As dilute solutions in chloroform, tweezers 1 displays both pyrene monomer and excimer emission features reflecting intramolecular contacts between the pyrene subunits. At higher concentrations in chloroform, as well as in the solid state, tweezers 1 self-assembles to form a linear supramolecular polymer. In contrast, tweezers 2 does not interact in an intermolecular fashion and photoexcitation produces emission features characteristic of a pyrene monomer. DFT (density functional theory) and TDDFT (time dependent density functional theory) calculations revealed that the lowest vertical transitions are forbidden and that S-1 of 1 is an emissive state. In contrast to 1 and 2, both pyrene-free control systems 5 and 6 were found to form linearly self-assembled supramolecular arrays in the solid state, albeit of differing structure. Upon exposure to trinitrobenzene (TNB), the self-assembled structures formed from 1 undergo deaggregation to form TNB complexes. This change is reflected in both an easily discernible color change and a quenching of the fluorescence emission intensity. Changes in the optical features were also seen in the case of 2. However, notable differences between these two ostensibly similar systems were seen.

  DOI：

  10.1021/ja411672f

文献信息

• Self-Association and Nitroaromatic-Induced Deaggregation of Pyrene Substituted Pyridine Amides
  作者：Sung Kuk Kim、Jong Min Lim、Tuhin Pradhan、Hyo Sung Jung、Vincent M. Lynch、Jong Seung Kim、Dongho Kim、Jonathan L. Sessler

  DOI：10.1021/ja411672f

  日期：2014.1.8

  The self-assembly features of the bis-pyrene methyl amide functionalized pyridine and benzene "tweezers" 1 and 2 were studied in organic solution and in the solid state. These systems were found to display remarkably different self-association features and optical properties, which was rationalized by control experiments using compounds bearing pyrenemethyl esters, alkyl groups, or a single pyrene substituent (3-6). As dilute solutions in chloroform, tweezers 1 displays both pyrene monomer and excimer emission features reflecting intramolecular contacts between the pyrene subunits. At higher concentrations in chloroform, as well as in the solid state, tweezers 1 self-assembles to form a linear supramolecular polymer. In contrast, tweezers 2 does not interact in an intermolecular fashion and photoexcitation produces emission features characteristic of a pyrene monomer. DFT (density functional theory) and TDDFT (time dependent density functional theory) calculations revealed that the lowest vertical transitions are forbidden and that S-1 of 1 is an emissive state. In contrast to 1 and 2, both pyrene-free control systems 5 and 6 were found to form linearly self-assembled supramolecular arrays in the solid state, albeit of differing structure. Upon exposure to trinitrobenzene (TNB), the self-assembled structures formed from 1 undergo deaggregation to form TNB complexes. This change is reflected in both an easily discernible color change and a quenching of the fluorescence emission intensity. Changes in the optical features were also seen in the case of 2. However, notable differences between these two ostensibly similar systems were seen.