Diagnostic method for neurodegenerative diseases based on measurement of SIRT1 levels or activity
申请人:The President and Fellows of Harvard College
公开号:EP2362226A1
公开(公告)日:2011-08-31
Provided herein are methods and compositions for modulating the activity of sirtuin deacetylase protein family members; p53 activity; apoptosis; lifespan and sensitivity to stress of cells and organisms. Exemplary methods comprise contacting a cell with an activating compound, such as flavone, stilbene, flavanone, isoflavone, catechin, chalcone, tannin or anthocyanidin; or an inhibitory compound, such as a sphingolipid, e.g., sphingosine. Also disclosed herein are methods for treating, preventing or diagnosing a disease associated with neuronal cell death, e.g., a neurodegenerative disease.
METHOD FOR MAKING AN AMBIENT LIGHT CURABLE ETHYLENE PROPYLENE DIENE TERPOLYMER RUBBER COATING DEVOID OF THERMALLY ACTIVATED ACCELERATORS
申请人:LION COPOLYMER GEISMAR, LLC
公开号:US20140228469A1
公开(公告)日:2014-08-14
A durable ambient light curable waterproof liquid rubber coating with volatile organic compound (VOC) content of less than 450 grams per liter made from ethylene propylene diene terpolymer (EPDM) in a solvent, a photoinitiator, an additive, pigments, and fillers, and a co-agent and a method for making the formulation, wherein the formulation is devoid of thermally activated accelerators.
QUATERNARY FATTY ACID ESTERS AS CORROSION INHIBITORS
申请人:Ecolab USA Inc.
公开号:US20150240365A1
公开(公告)日:2015-08-27
Corrosion inhibitor compositions, methods of inhibiting or reducing corrosion, and methods of manufacturing corrosion inhibitor compositions are disclosed herein. In certain methods, the corrosion inhibitor compositions may be added to an aqueous industrial system having at least one surface. The aqueous industrial system may be a water recirculating system, a cooling water system, a boiler water system, a pulp slurry, a papermaking process, a ceramic slurry, a mixed solid/liquid system, or an oil-field system. A method of manufacturing a corrosion inhibitor composition may include reacting an alkanolamine with a fatty acid to form a fatty acid ester reaction product and reacting the fatty acid ester reaction product with an alkyl halide or an acrylate.