1-(3,4-dioxymethylenephenyl)propyl acetate | 73455-01-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并间二氧杂环戊烯类
• 英文名称: 1-(3,4-dioxymethylenephenyl)propyl acetate
• 英文别名: 1-(benzo[d]dioxol-5-yl)propyl acetate；acetic acid-(1-benzo[1,3]dioxol-5-yl-propyl ester)；Essigsaeure-(1-benzo[1,3]dioxol-5-yl-propylester)；1-Acetoxy-1-benzo[1,3]dioxol-5-yl-propan；1'-Acetoxy-2',3'-dihydrosafrole；1-(1,3-benzodioxol-5-yl)propyl acetate
• CAS: 73455-01-3
• 化学式: C₁₂H₁₄O₄
• 分子量: 222.241
• InChiKey: YDTOHZACIWPXLF-UHFFFAOYSA-N

物化性质

• 沸点：
  144-146 °C(Press: 11 Torr)
• 密度：
  1.1601 g/cm3(Temp: 27 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  异黄樟素 在 盐酸 作用下， 生成 1-(3,4-dioxymethylenephenyl)propyl acetate
  参考文献：
  名称：

  Ichikawa; Togashi, Nippon Kagaku Zasshi, 1950, vol. 71, p. 598

  摘要：

  DOI：

文献信息

• A novel synthesis of isoeugenol, [ring-(U)-¹⁴C]
  作者：John E. Immoos

  DOI：10.1002/jlcr.3329

  日期：2015.9.10

  A novel method for the preparation of isoeugenol, [ring-(U)-14C] is presented. Phenols and phenyl esters substituted in the para position with 1-hydroxyethyl or 1-hydroxypropyl acetate esters when treated with 1,8-diazabicyclo[5.4.0]undec-7-ene in dimethylformamide (DMF) eliminate the alkyl carboxylate function to give the unsaturated compound. The reaction fails with unsubstituted or ether substituted phenyl 1-hydroxyacetate esters.

  本文介绍了一种制备异丁香酚[环-(U)-14C]的新方法。在二甲基甲酰胺（DMF）中，用 1,8-二氮杂双环[5.4.0]十一-7-烯处理 1- 羟乙基或 1- 羟丙基乙酸酯取代对位的苯酚和苯酯时，会消除烷基羧酸酯的功能，从而得到不饱和化合物。未取代或醚取代的 1-羟基乙酸苯酯反应失败。
• Coagulant for separating serum or plasma from whole blood for use in blood examination procedures
  申请人：Nippon Paint Co., Ltd.

  公开号：EP0196533A1

  公开（公告）日：1986-10-08

  A coagulant or hemostatic comprises, as an effective ingredient, at least one compound consisting of a lignan skelton having oxygen-containing side chains or rings:

  凝血剂或止血剂作为有效成分，至少包含一种由木质素蛋白胨组成的化合物，该蛋白胨具有含氧侧链或环：
• Mameli, Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, 1904, vol. <5> 13 II, p. 320
  作者：Mameli

  DOI：——

  日期：——
• DDQ catalyzed benzylic acetoxylation of arylalkanes: a case of exquisitely controlled oxidation under sonochemical activation
  作者：Vinod Kumar、Abhishek Sharma、Meenakshi Sharma、Upendra K. Sharma、Arun K. Sinha

  DOI：10.1016/j.tet.2007.07.018

  日期：2007.9

  Acetoxylated arylalkanes are selectively obtained via sonochemical activation of DDQ catalyzed benzylic oxidation of arylalkanes in the presence of anhydrous acetic acid. The method gives an exquisite control of benzylic acetoxylation under ultrasound, in contrast to the uncontrolled oxidation observed under conventional heating or microwave activation. In addition, the developed method could be a useful strategy for the synthesis of industrially important enantiopure benzyl alcohols due to the easy amenability of obtained acetoxylated products toward chiral resolution. (c) 2007 Elsevier Ltd. All rights reserved.
• US4803153A
  申请人：——

  公开号：US4803153A

  公开（公告）日：1989-02-07