4-dimethylaminopropyloxy benzophenone | 120692-35-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-dimethylaminopropyloxy benzophenone
• 英文别名: [4-[3-(Dimethylamino)propoxy]phenyl]-phenylmethanone
• CAS: 120692-35-5
• 化学式: C₁₈H₂₁NO₂
• 分子量: 283.37
• InChiKey: GDAKRXFUQAIKOF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (Propionylcyclopentadienyl)tricarbonylmanganese 、 4-dimethylaminopropyloxy benzophenone 在 TiCl₄ 、 Zn 作用下， 以 四氢呋喃 为溶剂， 以54%的产率得到1-phenyl-1-(4-dimethylaminopropyloxyphenyl)-2-cymantrenyl-1-butene
  参考文献：
  名称：

  The first titanocenyl dichloride moiety vectorised by a selective estrogen receptor modulator (SERM). Synthesis and preliminary biochemical behaviour

  摘要：

  The synthesis of 4'. a titanocene derivative of the anticancer drug tamoxifen is presented together with its biochemical properties. Compound 4' is prepared by a McMurry coupling followed by a ligand exchange. Compound 4' reveals an unexpected proliferative effect on the hormone-dependent cell line MCF7. Surprisingly this effect is also observed with Cp2TiCl2 alone. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(01)01271-2
• 作为产物：
  描述：

  N,N-二甲氨基氯丙烷盐酸盐 、 4-羟基-二苯甲酮 在 sodium hydroxide 作用下， 以 丙酮 为溶剂， 反应 15.25h， 以77%的产率得到4-dimethylaminopropyloxy benzophenone
  参考文献：
  名称：

  The first titanocenyl dichloride moiety vectorised by a selective estrogen receptor modulator (SERM). Synthesis and preliminary biochemical behaviour

  摘要：

  The synthesis of 4'. a titanocene derivative of the anticancer drug tamoxifen is presented together with its biochemical properties. Compound 4' is prepared by a McMurry coupling followed by a ligand exchange. Compound 4' reveals an unexpected proliferative effect on the hormone-dependent cell line MCF7. Surprisingly this effect is also observed with Cp2TiCl2 alone. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(01)01271-2

文献信息

• POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS
  申请人：Loccufier Johan

  公开号：US20110063388A1

  公开（公告）日：2011-03-17

  A polymerizable Type II photoinitiator according to Formula (I): wherein: A represents a Norrish Type II initiating group; L represents a divalent linking group positioning the Norrish Type II initiating group A and the CR2R3-group in a 1-5 to a 1-8 position wherein position 1 is defined as the first atom in the aromatic or alicyclic ring of A to which L is covalently bonded and the position 5 to 8 is defined as the carbon atom of the CR2R3-group to which L is covalently bonded, with the proviso that L does not contain an amine. Radiation curable compositions and inks include the multifunctional Type II photoinitiator.

  一种可聚合的二型光引发剂，其化学式为（I）：其中：A代表Norrish二型引发基团；L代表二价连接基团，将Norrish二型引发基团A和CR2R3基团定位在1-5到1-8位置之间，其中位置1定义为A芳香或螺环的第一个原子，与L共价键合，位置5到8定义为CR2R3基团的碳原子，与L共价键合，但L不含胺基。辐射可固化组合物和油墨包括多功能二型光引发剂。
• MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS
  申请人：Loccufier Johan

  公开号：US20110069130A1

  公开（公告）日：2011-03-24

  A multifunctional Type II photoinitiator according to Formula (I): wherein X represents a structural moiety according to Formula (II): wherein: A represents a Norrish Type II initiating group; and L represents a divalent linking group positioning the Norrish Type II initiating group A and the CR2R3-group in a 1-5 to a 1-9 position wherein position 1 is defined as the first atom in the aromatic or alicyclic ring of A to which L is covalently bonded and the position 5 to 9 is defined as the carbon atom of the CR2R3-group to which L is covalently bonded, with the proviso that L does not contain an amine. Radiation curable compositions and inks include the multifunctional Type II photoinitiator.

  一种多功能的二型光引发剂，其化学式为(I)：其中X代表化学式(II)的结构基团：其中：A代表Norrish二型引发基团；L代表二价连结基团，将Norrish二型引发基团A和CR2R3基团定位于1-5到1-9的位置，其中位置1定义为A芳香环或脂环中与L共价结合的第一个原子，位置5到9定义为CR2R3基团中与L共价结合的碳原子，但L不包含胺基。辐射可固化组合物和油墨包括该多功能二型光引发剂。
• Radiation curable inkjet fluids and inks improved for photoyellowing
  申请人：Agfa Graphics N.V.

  公开号：EP2053102A1

  公开（公告）日：2009-04-29

  A radiation curable inkjet fluid including a radiation curable composition comprising at least 25 wt% of a vinylether acrylate and at least 15 wt% of a polymerizable compound comprising at least three acrylate groups; and a photoinitiator comprising a tertiary amine group and 0 to 3 wt% of isopropylthioxanthone. An inkjet printing method is also disclosed.

  一种辐射固化喷墨流体，包括一种辐射固化组合物，该组合物包含至少 25 wt%的乙烯基醚丙烯酸酯和至少 15 wt%的包含至少三个丙烯酸酯基团的可聚合化合物；以及 光引发剂，包括叔胺基团和 0 至 3 wt%的异丙基硫杂蒽酮。 还公开了一种喷墨打印方法。
• Crystal Structure and Conformational Analysis of N, N-dimethyl-N-[3-(benzoyl-4-phenoxy)propyl]-N-n-dodecyl-ammonium bromide: Molecule acting as UV filter
  作者：Cecilia Anselmi、Marisanna Centini、Mirella Scotton、Alessandro Sega、P. Dapporto、P. Paoli

  DOI：10.1002/prac.19923340205

  日期：——

  The solid state conformation of the title compound was determined. Conformational analysis based on molecular modelling mechanics allowed the calculation of the energy of the most stable conformers and their comparison with X-ray conformation.
• RADIATION CURABLE INKJET FLUIDS AND INKS IMPROVED FOR PHOTOYELLOWING
  申请人：Loccufier Johan

  公开号：US20100330296A1

  公开（公告）日：2010-12-30

  A radiation curable inkjet fluid includes a radiation curable composition including at least 25 wt % of a vinylether acrylate and at least 15 wt % of a polymerizable compound including at least three acrylate groups, each wt % being based upon the total weight of the radiation curable composition; and a photoinitiator including a tertiary amine group and 0 to 3 wt % of isopropylthioxanthone based upon the total weight of the radiation curable inkjet fluid. Also, an inkjet printing method using the radiation curable inkjet fluid.