3-butyloxy-2,2-dimethylpropionic acid | 125181-32-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-butyloxy-2,2-dimethylpropionic acid
• 英文别名: 3-Butoxy-2,2-dimethylpropanoic acid
• CAS: 125181-32-0
• 化学式: C₉H₁₈O₃
• 分子量: 174.24
• InChiKey: CJTKLGXZALTIEI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  氯甲基氯磺酸酯 、 四丁基硫酸氢铵 、 3-butyloxy-2,2-dimethylpropionic acid 生成 chloromethyl 3-butoxy-2,2-dimethylpropanoate
  参考文献：
  名称：

  ADAM, FRIEDHELM;BLUMBACH, JURGEN;DURCKHEIMER, WALTER;FISCHER, GERD;MENCKE+

  摘要：

  DOI：
• 作为产物：
  描述：

  ethyl 3-butoxy-2,2-dimethylpropanoate 以74%的产率得到
  参考文献：
  名称：

  ADAM, FRIEDHELM;BLUMBACH, JURGEN;DURCKHEIMER, WALTER;FISCHER, GERD;MENCKE+

  摘要：

  DOI：

文献信息

• Heterogeneously Catalysed Synthesis of New 3-Alkoxypivalic Acids from Substituted 1,3-Dioxanes
  作者：Jutta Fischer、Wolfgang F. Hölderich

  DOI：10.1006/jcat.2000.2956

  日期：2000.9

  3-alkyloxypivalic acids starting from substituted 1,3-dioxanes were examined. While one-step procedures combining isomerisation and oxidation were not successful due to degradation of formed intermediates and products, a two-step environmentally benign method could be established using O2 as oxidant in the presence of heterogeneous catalysts. The scope of the method was tested by use of several 1,3-dioxanes and

  从取代的1，3-二恶烷开始，研究了几种制备有趣和有价值的化合物3-烷氧基新戊酸的方法。尽管由于形成的中间体和产物的降解，将异构化和氧化相结合的一步法不成功，但是可以在异相催化剂存在下使用O 2作为氧化剂建立一种两步法环境友好的方法。该方法的范围通过使用几种1,3-二恶烷进行了测试，并对分离出的新戊酸衍生物进行了表征。
• Novel compositions of material, especially lubricants and pressure transmitting means, the production and use thereof
  申请人：——

  公开号：US20030186823A1

  公开（公告）日：2003-10-02

  The invention relates to novel compositions of matter which may advantageously be used as lubricants or pressure transfer media or else for functional liquids and lubricant additives. The lubricants according to the invention are the reaction products of an electro-philic addition of linear or branched, aliphatic or aromatic carboxylic acids, carboxylic anhydrides, carbonyl halides or novel neoacids to the double bonds of fatty acids, esters thereof and/or of other fatty acid derivatives and also of synthetic esters. Owing to their increased oxidation resistance compared to the starting materials and also their low toxicity, the novel class of synthetic esters based on oleochemicals may find use in novel environmentally compatible lubricants, pressure transfer systems, functional liquids and lubricant additives.

  本发明涉及一种新型物质组成，可优势地用作润滑剂或压力传递介质，或者用于功能液体和润滑剂添加剂。根据本发明，润滑剂是线性或支链的，脂肪族或芳香族羧酸，羧酸酐，羰基卤化物或新型新酸通过亲电加成反应与脂肪酸，其酯和/或其他脂肪酸衍生物以及合成酯的双键反应生成的产物。由于与起始材料相比具有较高的氧化抵抗性和低毒性，基于油脂化学的新型合成酯类可以用于新型环境兼容的润滑剂、压力传递系统、功能液体和润滑剂添加剂。
• CGRP RECEPTOR ANTAGONISTS WITH TERTIARY AMIDE, SULFONAMIDE, CARBAMITE AND UREA GROUPS
  申请人：Wood Michael R

  公开号：US20100292263A1

  公开（公告）日：2010-11-18

  Compounds of formula I: (wherein variables A, m, n, J, R e , R f , R 4 , E a , E b , E c , R PG and Y are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine; and pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

  公式I的化合物：（其中变量A，m，n，J，Re，Rf，R4，Ea，Eb，Ec，RPG和Y如本文所述），这些化合物是CGRP受体拮抗剂，可用于治疗或预防CGRP参与的疾病，例如偏头痛；以及包含这些化合物的制药组合物和使用这些化合物和组合物预防或治疗CGRP参与的这些疾病。
• Thermoplastic resin composition
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0356194A2

  公开（公告）日：1990-02-28

  A thermoplastic resin composition which has excellent heat resistance and impact resistance as well as excellent rigidity, chemical resistance and processibility, comprises: (a) a polyphenylene ether resin or a resin composition containing a polyphenylene ether, (b) either a modified propylene polymer grafted with a styrene-based monomer and an unsaturated carboxylic acid or its derivative, or a propylene-based resin composition containing the modified propylene polymer and a propylene polymer, and (c) a rubbery substance. The thermoplastic resin compositions not only have good mold-processibility but also exhibit well-balanced physical properties when molded into articles such as vehicle components.

  一种具有优异的耐热性和抗冲击性以及优异的刚性、耐化学性和可加工性的热塑性树脂组合物，包括 (a) 聚苯醚树脂或含有聚苯醚的树脂组合物、 (b) 接枝了苯乙烯基单体和不饱和羧酸或其衍生物的改性丙烯聚合物，或含有改性丙烯聚合物和丙烯聚合物的丙烯基树脂组合物，以及 (c) 橡胶物质。 这种热塑性树脂组合物不仅具有良好的模塑加工性，而且在模塑成汽车部件等物品时，还能表现出均衡的物理性能。
• Glass fiber-reinforced resin composition
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0404303A1

  公开（公告）日：1990-12-27

  A resin composition which has favorable mold processability and a superior balance of various physical properties comprises (a) polyphenylene ether or polyphenylene ether-­containing resin composition, (b) propylene polymer, (c) propylene polymer modified with an oxygen-­containing unsaturated organic compound, (d) optionally, rubber-like substance, and (e) glass fiber treated with a silane compound on its surface.

  一种树脂组合物具有良好的模具加工性和各种物理性能的卓越平衡，包括 (a) 聚苯醚或含聚苯醚的树脂组合物、 (b) 丙烯聚合物 (c) 用含氧不饱和有机化合物改性的丙烯聚合物、 (d) 可选的橡胶状物质，以及 (e) 表面经硅烷化合物处理的玻璃纤维。