2-己基十二烷-1-醇 | 110225-00-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-己基十二烷-1-醇
• 英文名称: 2-hexyl-1-dodecanol
• 英文别名: 2-decyl-octan-1-ol；2-hexyldodecanol；7-hydroxymethyl-heptadecane；7-Hydroxymethyl-heptadecan；2-hexyl dodecanol；2-hexyl-dodecanol；1-Dodecanol, 2-hexyl-；2-hexyldodecan-1-ol
• CAS: 110225-00-8
• 化学式: C₁₈H₃₈O
• 分子量: 270.499
• InChiKey: LOIMOHMWAXGSLR-UHFFFAOYSA-N

物化性质

• LogP：
  7.815 (est)
• 物理描述：
  Liquid

计算性质

• 辛醇/水分配系数(LogP)：
  8.1
• 重原子数：
  19
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-己基十二烷-1-醇 、 alkaline earth salt of/the/ methylsulfuric acid 在 苯 作用下， 生成 (4'-chloro-biphenyl-4-yl)-carbamic acid-(2-hexyl-dodecyl ester)
  参考文献：
  名称：

  Brunner; Wiedemann, Monatshefte fur Chemie, 1935, vol. 66, p. 441

  摘要：

  DOI：
• 作为产物：
  描述：

  辛醇 、 癸醇 、 镍 在 氢氧化钾 作用下， 以90%的产率得到2-己基十二烷-1-醇
  参考文献：
  名称：

  Propoxylated guerbet alcohols and esters thereof

  摘要：

  本发明涉及具有碘值小于7且由通用公式定义的丙氧基格贝醇和酯：##STR1## 这些醇和酯可以单独或混合使用，作为金属加工中的润滑剂。

  公开号：

  US04830769A1

文献信息

• COMPOSITION CONTAINING A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND COSMETIC TREATMENT PROCESS
  申请人：CHODOROWSKI-KIMMES Sandrine

  公开号：US20100028277A1

  公开（公告）日：2010-02-04

  Composition containing, in a cosmetically or dermatologically acceptable medium, a compound that may be obtained by reaction between: an oil bearing at least one nucleophilic and/or electrophilic reactive function, and a junction group capable of establishing hydrogen bonds with one or more partner junction groups, the junction group bearing at least one reactive function capable of reacting with the reactive function borne by the oil, and also comprising at least one unit of formula (I) or (II):

  含有一种化合物的成分，可以通过以下反应获得：一个至少带有一个亲核和/或亲电反应功能的油，以及一个能够与一个或多个配对连接基建立氢键的连接基，该连接基至少带有一个能够与油所带反应功能发生反应的反应功能，并且还包括至少一个符合式(I)或(II)的单元的化妆品或皮肤学上可接受的介质。
• Polyether-modified polymers as leather auxiliaries
  申请人：Reiners Juergen

  公开号：US20050058619A1

  公开（公告）日：2005-03-17

  (Co)polymers which contain a) structural units of the general formula I in which W represents a trivalent radical from the group in which * indicates the orientation for the incorporation of the radical W into the formula I, and Z represents the radicals —OH, —O − M + or —N—R 1 R 2 , in which R 1 and R 2 , independently of one another, represent hydrogen, optionally substituted alkyl radicals, alkenyl radicals, aralkyl radicals or cycloalkyl radicals, which may be interrupted by 0 atoms, N atoms, Si atoms or amido, carbonate, urethane, urea, allophanate, biuret or isocyanurate groups or mixtures thereof, and M + represents H + or an alkali metal ion, an NH 4 ion or a primary, secondary, tertiary or quaternary aliphatic ammonium radical which preferably carries a C 1 -C 22 -alkyl or C 1 -C 22 -hydroxyalkyl group, b) at least 10 mol %, based on the units of the formula I, of structural units of the general formula Ia in which R 3 represents a hydrocarbon radical having C 1 -C 60 -atoms, preferably a saturated C 1 -C 60 -alkyl radical, in particular C 12 -C 30 -alkyl radical, and R 4 represents hydrogen or has the same meaning as R 3 , and e) polyether units having an average molecular weight of 200 - 6000 g/mol.

  聚合物包含a) 通式I的结构单元，其中W代表来自该组的三价基团，其中*表示将基团W合并到通式I中的取向，Z代表基团—OH，—O−M+或—N—R1R2，其中R1和R2独立地表示氢，可选择地取代的烷基基团，烯基基团，芳基烷基基团或环烷基基团，可以由0个原子，N原子，Si原子或酰胺，碳酸酯，脲，脲，异氰酸酯，双脲基或异氰酸酯基团或它们的混合物中断，并且M+表示H+或碱金属离子，NH4离子或一种一级，二级，三级或季铵基团，最好携带C1-C22-烷基或C1-C22-羟基烷基基团，b)至少占通式I单位的10摩尔％的通式Ia的结构单元，其中R3代表具有C1-C60原子的碳氢基团，优选为饱和的C1-C60烷基基团，特别是C12-C30烷基基团，和R4代表氢或具有与R3相同的含义，以及e) 平均分子量为200-6000g/mol的聚醚单元。
• [EN] GUERBET CONDENSATION REACTION<br/>[FR] RÉACTION DE CONDENSATION DE GUERBET
  申请人：UNIV GENT

  公开号：WO2017093473A1

  公开（公告）日：2017-06-08

  The invention relates to a process for the preparation of a Guerbet alcohol, comprising the steps of: (a) providing at least one alcohol, wherein said at least one alcohol has a carbon atom bearing at least one hydrogen atom adjacent to the hydroxyl group; (b) providing a catalyst composition, wherein said catalyst composition comprises an alkaline catalyst and a copper-nickel catalyst comprised in a hydrotalcite; (c) mixing alcohol (a) with catalyst composition (b), thereby obtaining a mixture; and, (d) heating said mixture; thereby obtaining a Guerbet alcohol.

  这项发明涉及一种制备Guerbet醇的过程，包括以下步骤：(a)提供至少一种醇，其中所述至少一种醇具有至少一个碳原子，其上带有至少一个与羟基相邻的氢原子；(b)提供催化剂组合物，其中所述催化剂组合物包括碱性催化剂和铜-镍催化剂，其包含在水滑石中；(c)将醇(a)与催化剂组合物(b)混合，从而获得混合物；以及(d)加热所述混合物；从而获得Guerbet醇。
• PROCESS FOR DYEING HAIR
  申请人：Henkel AG & Co. KGaA

  公开号：US20200397684A1

  公开（公告）日：2020-12-24

  The subject of the present disclosure is a process for dyeing human hair, in which a pretreatment agent (A) which contains at least one organic silicon compound of the formula (I) and/or (II) and contains no direct dyes and no pigments, and a colorant (B) which contains at least one organic silicon compound of the formula (I) and/or (II) and further contains at least one colorant compound from the group of direct dyes and/or pigments, can be applied to the hair, wherein the organic silicon compounds of formulae (I) and (II) are defined as follows R 1 R 2 N-L-Si(OR 3 ) a (R 4 ) b (I), (R 5 O) c (R 6 ) d Si-(A) e -[NR 7 -(A′)] f —[O-(A″)] g -[NR 8 -(A′″)] h —Si(R 6 ′) d′ (OR 5 ′) c′ (II).

  本公开的主题是一种染色人类头发的过程，其中可以将含有至少一种有机硅化合物公式(I)和/或(II)且不含有直接染料和颜料的预处理剂(A)，和含有至少一种有机硅化合物公式(I)和/或(II)且进一步含有直接染料和/或颜料化合物群中的至少一种颜料化合物的染料剂(B)应用于头发上。其中，公式(I)和(II)的有机硅化合物定义如下：R1R2N-L-Si(OR3)a(R4)b(I)，(R5O)c(R6)dSi-(A)e-[NR7-(A′)]f—[O-(A″)]g-[NR8-(A′″)]h—Si(R6′)d′(OR5′)c′(II)。
• TRANSDERMAL ABSORPTION PREPARATION
  申请人：Nitto Denko Corporation

  公开号：US20180311362A1

  公开（公告）日：2018-11-01

  Provided is a transdermal absorption preparation that shows superior skin permeability of a drug and that does not easily cause cold flow. A transdermal absorption preparation having a drug-containing layer containing a drug and a polymer, wherein 50-100 wt % of the polymer in the drug-containing layer is a polymer having a glass transition temperature of 30° C.-200° C., and the drug in the drug-containing layer is in an amorphous state.

  提供了一种经皮吸收制剂，该制剂具有卓越的药物皮肤渗透性，且不易引起冷流现象。该经皮吸收制剂包括一种药物含量层，其中包含药物和聚合物，其中药物含量层中的聚合物的50-100重量％为具有30℃-200℃玻璃转移温度的聚合物，而药物则处于非晶态。