2-庚基吡啶 | 20815-27-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 2-庚基吡啶
• 英文名称: 2-heptylpyridine
• CAS: 20815-27-4
• 化学式: C₁₂H₁₉N
• 分子量: 177.29
• InChiKey: DYCPESWJKDONHC-UHFFFAOYSA-N

物化性质

• 沸点：
  244.9±3.0 °C(Predicted)
• 密度：
  0.895±0.06 g/cm3(Predicted)
• LogP：
  4.370 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2933399090

反应信息

• 作为反应物：
  描述：

  2-庚基吡啶 在 哌啶 、 bis-triphenylphosphine-palladium(II) chloride 、 potassium acetate 作用下， 以 N-甲基吡咯烷酮 、 氯仿 、 丙酮 为溶剂， 反应 69.0h， 生成 3-(thiophen-2'-yl-5'-2-phenyl-3-hexylindolizine)-2-cyano-2-propenoic acid
  参考文献：
  名称：

  [EN] INDOLIZINE-BASED DYES FOR DYE-SENSITIZED SOLAR CELL
  [FR] COLORANTS À BASE D'INDOLIZINE POUR CELLULE SOLAIRE SENSIBILISÉE PAR COLORANT

  摘要：

  用作染料敏化太阳能电池中感光染料的化合物。

  公开号：

  WO2016019182A1
• 作为产物：
  描述：

  2-庚-6-炔基-吡啶 在 乙醇 、 镍 作用下， 生成 2-庚基吡啶
  参考文献：
  名称：

  Gautier et al., Bulletin de la Societe Chimique de France, 1958, p. 415,416

  摘要：

  DOI：

文献信息

• Selective and Serial Suzuki–Miyaura Reactions of Polychlorinated Aromatics with Alkyl Pinacol Boronic Esters
  作者：Sébastien Laulhé、J. Miles Blackburn、Jennifer L. Roizen

  DOI：10.1021/acs.orglett.6b02323

  日期：2016.9.2

  availability and low toxicity of the required reagents, mild reaction conditions, and functional group compatibility. Nevertheless, few conditions can be used to cross-couple alkyl boronic acids or esters with aryl halides, especially 2-pyridyl halides. Herein, we describe two novel Suzuki–Miyaura protocols that enable selective conversion of polychlorinated aromatics, with a focus on reactions to convert

  在交叉偶联反应中，Suzuki-Miyaura转化因其实际优势而脱颖而出，其中包括商业上可获得的试剂和所需试剂的低毒性，温和的反应条件以及官能团的相容性。然而，几乎没有条件可用于烷基硼酸或酯与芳基卤化物，特别是2-吡啶基卤化物的交联。在这里，我们描述了两个新颖的Suzuki-Miyaura协议，它们能够选择性地转换多氯代芳烃，重点是将2，6-二氯吡啶转化为2-氯-6-烷基吡啶或2-芳基-6-烷基吡啶的反应。
• PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE
  申请人：Okamoto Kuniaki

  公开号：US20120130107A1

  公开（公告）日：2012-05-24

  Object To provide a method for producing a bis-quaternary ammonium salt efficiently and a novel synthetic intermediate thereof. Solution The present invention relates to a method for producing a bis-quaternary ammonium salt represented by a general formula [3] which comprises reacting a disulfonic acid ester represented by a general formula [1] (in the formula, definitions of two R 1 's and T are as described in claim 1 ) with a tertiary amine represented by a general formula [2] (in the formula, definitions of R 3 to R 5 are as described in claim 1 ), and a disulfonic acid ester represented by a general formula [1′] (in the formula, two R 16 's represent independently a halogen atom or a C1-C3 fluoroalkyl group, and two m's represent independently an integer of 1 to 5).

  提供一种高效生产双季铵盐和其新型合成中间体的方法。本发明涉及一种生产由通用式[3]表示的双季铵盐的方法，包括将由通用式[1]表示的二磺酸酯（在该式中，两个R1和T的定义如权利要求1中所述）与由通用式[2]表示的三级胺（在该式中，R3到R5的定义如权利要求1中所述）以及由通用式[1']表示的二磺酸酯（在该式中，两个R16独立表示卤原子或C1-C3氟烷基，两个m独立表示1至5的整数）反应。
• Palladium-Catalyzed Amino-Heck Reaction of γ,δ-Unsaturated Ketone <i>O</i>-Diethylphosphinyloximes: A New Synthesis of Substituted Pyrroles and Indoles
  作者：Jia-Liang Zhu*、Yu-Hui Chan

  DOI：10.1055/s-2008-1072728

  日期：2008.5

  starting materials for the intramolecular amino-Heck reactions. In the presence of a catalytic amount of Pd(PPh 3 ) 4 in DBU, cyclization reactions occurred preferentially via a 5- EXO fashion to afford a variety of 2-substituted 5-methyl-1 H-pyrroles and several indole derivatives in moderate to high yields.

  γ,δ-不饱和酮 O-二乙基膦肟很容易由相应的酮制备，用作分子内氨基-Heck 反应的起始材料。在 DBU 中存在催化量的 Pd(PPh 3 ) 4 时，环化反应优先通过 5-EXO 方式发生，以提供各种 2-取代的 5-甲基-1 H-吡咯和几种吲哚衍生物。高产量。
• Enantioselective Alkylation of 2-Alkylpyridines Controlled by Organolithium Aggregation
  作者：Joshua J. Gladfelder、Santanu Ghosh、Maša Podunavac、Andrew W. Cook、Yun Ma、Ryan A. Woltornist、Ivan Keresztes、Trevor W. Hayton、David B. Collum、Armen Zakarian

  DOI：10.1021/jacs.9b08659

  日期：2019.9.25

  pyridines provides access to chiral pyridines via an opera- tionally simple protocol that obviates the need for prefunc- tionalization or preactivation of the substrate. The alkylation is accomplished using chiral lithium amides as non-covalent stereodirecting auxiliaries. Crystallographic and solution NMR studies provide insight into the structure of well- defined chiral aggregates in which a lithium

  2-烷基吡啶的直接对映选择性α-烷基化通过操作简单的方案提供了获得手性吡啶的途径，无需对底物进行预官能化或预活化。使用手性氨基化锂作为非共价立体定向助剂完成烷基化。晶体学和溶液 NMR 研究提供了对明确定义的手性聚集体结构的洞察，其中氨基锂试剂引导不对称烷基化。
• IONIC LIQUID CONTAINING ALLYLSULFONATE ANION
  申请人：Watahiki Tsutomu

  公开号：US20120157680A1

  公开（公告）日：2012-06-21

  PROBLEM: Providing a novel ionic liquid, which is low-cost, environment-friendly, and has low viscosity and melting point. MEANS FOR SOLVING THE PROBLEM: The present invention is the invention of the ionic liquid represented by the general formula [1]: wherein, R 1 to R 3 and n pieces of R 4 each independently represent hydrogen atom or alkyl group having 1 to 4 carbon atoms, R 5 to R 7 each independently represent alkyl group, aralkyl group, or aryl group, R 8 represents alkyl group, aralkyl group, aryl group, or the one represented by the general formula [2]: (wherein T represents alkylene chain having 1 to 8 carbon atoms, n represents 1 or 2, and R 1 to R 7 are the same as the above-described), X represents nitrogen atom or phosphorus atom, n represents 1 or 2. When n is 1, R 3 and R 4 are bound and may form cyclohexene ring together with the adjacent carbon atoms. In addition, when X is nitrogen atom, R 5 to R 7 or R 5 to R 6 may form hetero ring with nitrogen atom binding thereto}.

  问题：提供一种新型离子液体，成本低、环保，并具有低粘度和熔点。 解决问题的方法：本发明是一种由通式[1]表示的离子液体的发明：其中，R1到R3和n个R4分别独立表示氢原子或具有1到4个碳原子的烷基基团，R5到R7分别独立表示烷基基团、芳基烷基基团或芳基基团，R8表示烷基基团、芳基烷基基团、芳基基团或由通式[2]表示的基团：（其中T表示具有1到8个碳原子的烷基链，n表示1或2，R1到R7与上述相同），X表示氮原子或磷原子，n表示1或2。当n为1时，R3和R4结合并且可能与相邻碳原子一起形成环己烯环。此外，当X为氮原子时，R5到R7或R5到R6可能与结合在一起的氮原子形成杂环}。