3-bromo-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-6-carbonitrile | 1200130-53-5

分子结构分类

有机化合物 - 有机杂环化合物 - 吡咯并吡啶类

中文名称

——

中文别名

——

英文名称

3-bromo-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-6-carbonitrile

英文别名

3-bromo-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b:4',3'-d]pyrrole-6-carbonitrile；3-bromo-9-(2-trimethylsilanylethoxymethyl)-9H-dipyrido[2,3-b:4',3'-d]pyrrole-6-carbonitrile；3-Bromo-9-(2-trimethylsilanylethoxymethyl)-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile；12-bromo-8-(2-trimethylsilylethoxymethyl)-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile

3-bromo-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-6-carbonitrile化学式

CAS

1200130-53-5

化学式

C₁₇H₁₉BrN₄OSi

mdl

——

分子量

403.354

InChiKey

INUKRKHBSIWMAG-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

4.53
重原子数：

24
可旋转键数：

5
环数：

3.0
sp3杂化的碳原子比例：

0.35
拓扑面积：

63.7
氢给体数：

0
氢受体数：

4

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	3-bromo-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-6-carbonitrile	1200130-52-4	C₁₁H₅BrN₄	273.091
——	3-bromo-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-6-carboxamide	1200130-51-3	C₁₁H₇BrN₄O	291.107
——	methyl 3-bromo-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-6-carboxylate	1200130-50-2	C₁₂H₈BrN₃O₂	306.118

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	9-((2-(trimethylsilyl)ethoxy)methyl)-9H-pyrrolo[2,3-b:5,4-c′]-dipyridine-6-carbonitrile	1200130-63-7	C₁₇H₂₀N₄OSi	324.457
——	3-hydroxy-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-6-carbonitrile	1200130-59-1	C₁₇H₂₀N₄O₂Si	340.457
——	3-amino-9-(2-trimethylsilanylethoxymethyl)dipyrido[2,3-b:4',3'-d]pyrrole-6-carbonitrile	1200130-61-5	C₁₇H₂₁N₅OSi	339.472
——	3-chloro-9-(2-trimethylsilanylethoxymethyl)dipyrido[2,3-b:4',3'-d]pyrrole-6-carbonitrile	1200130-62-6	C₁₇H₁₉ClN₄OSi	358.903
——	4-hydroxy-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-83-1	C₁₇H₂₀N₄O₂Si	340.457
——	4-chloro-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1200130-66-0	C₁₇H₁₉ClN₄OSi	358.903
——	3-(4-hydroxymethylphenyl)-bromo-9-(2-trimethylsilanylethoxymethyl)-9H-dipyrido[2,3-b:4',3'-d]pyrrole-6-carbonitrile	1200130-57-9	C₂₄H₂₆N₄O₂Si	430.582
——	9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile-1,7-dioxide	1200130-64-8	C₁₇H₂₀N₄O₃Si	356.456
——	2-chloro-9-(2-trimethylsilanylethoxymethyl)dipyrido[2,3-b:4',3'-d]pyrrole-6-carbonitrile-7-oxide	1288958-95-1	C₁₇H₁₉ClN₄O₂Si	374.902
——	methanesulfonic acid 4-(6-cyano-9-(2-trimethylsilanylethoxymethyl)-9H-dipyrido[2,3-b:4',3'-d]pyrrol-3-yl)benzyl ester	1200130-58-0	C₂₅H₂₈N₄O₄SSi	508.673
——	tert-butyl (6-cyano-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridin-3-yl)carbamate	1200130-60-4	C₂₂H₂₉N₅O₃Si	439.589
——	4-(piperazin-1-yl)-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-81-9	C₂₁H₂₈N₆OSi	408.578
——	4-chloro-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile-7-dioxide	1200130-65-9	C₁₇H₁₉ClN₄O₂Si	374.902
——	(S)-4-(3-aminopyrrolidin-1-yl)-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312756-12-9	C₂₁H₂₈N₆OSi	408.578
——	3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-pyrrolo[2,3-b:5,4-c′]dipyridine-6-carbonitrile	1200130-54-6	C₂₃H₃₁BN₄O₃Si	450.421
——	(S)-4-(3-hydroxypyrrolidin-1-yl)-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-85-3	C₂₁H₂₇N₅O₂Si	409.563
——	(R)-4-(piperidin-3-yloxy)-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-97-7	C₂₂H₂₉N₅O₂Si	423.59
——	4-((4-methylpiperidin-4-yl)methoxy)-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-93-3	C₂₄H₃₃N₅O₂Si	451.644
——	(R)-4-(piperidin-3-ylmethoxy)-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-78-4	C₂₃H₃₁N₅O₂Si	437.617
——	(R)-4-(piperidin-2-ylmethoxy)-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312756-02-7	C₂₃H₃₁N₅O₂Si	437.617
——	4-((1-ethyl-4-methylpiperidin-4-yl)methoxy)-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido [2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-96-6	C₂₆H₃₇N₅O₂Si	479.698
——	4-((4-ethyl-1-methylpiperidin-4-yl)methoxy)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312756-01-6	C₂₆H₃₇N₅O₂Si	479.698
——	(R)-4-(1-methylpiperidin-3-yloxy)-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-98-8	C₂₃H₃₁N₅O₂Si	437.617
——	(R)-4-(1-methylpiperidin-3-ylmethoxy)-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-79-5	C₂₄H₃₃N₅O₂Si	451.644
——	(S)-4-(N-ethylpyrrolidin-3-amino)-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312756-06-1	C₂₃H₃₂N₆OSi	436.632
——	(R)-4-(1-ethylpiperidin-3-yloxy)-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-99-9	C₂₄H₃₃N₅O₂Si	451.644
——	4-(3-methylpiperidin-3-yloxy)-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-91-1	C₂₃H₃₁N₅O₂Si	437.617
——	4-((1-(2-methoxyethyl)-4-methylpiperidin-4-yl)methoxy)-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-95-5	C₂₇H₃₉N₅O₃Si	509.724
——	4-(1-(3-fluoropropyl)-4-methylpiperidin-4-yl)methoxyl-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-94-4	C₂₇H₃₈FN₅O₂Si	511.715
——	(R)-4-((1-methylpiperidin-2-yl)methoxy)-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312756-04-9	C₂₄H₃₃N₅O₂Si	451.644
——	(R)-4-((1-ethylpiperidin-2-yl)methoxy)-9-(2-trimethylsilanyl-ethoxymethyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312756-03-8	C₂₅H₃₅N₅O₂Si	465.671
——	(S)-4-(3-(2,2,2-trifluoroethylamino)pyrrolidin-1-yl)-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312756-13-0	C₂₃H₂₉F₃N₆OSi	490.604
——	tert-butyl 4-(6-cyano-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrol-4-yl)piperazine-1-carboxylate	1312753-96-0	C₂₆H₃₆N₆O₃Si	508.696
——	(S)-tert-butyl 1-(6-cyano-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrol-4-yl)pyrrolidin-3-ylcarbamate	1312755-87-5	C₂₆H₃₆N₆O₃Si	508.696
——	(R)-tert-butyl 3-((6-cyano-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-[2,3-b;4',3'-d]pyrrol-4-yloxy)methyl)piperidine-1-carboxylate	1312755-77-3	C₂₈H₃₉N₅O₄Si	537.734
——	(S)-tert-butyl 1-(6-cyano-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrol-4-yl)piperidin-3-ylcarbamate	1312753-95-9	C₂₇H₃₈N₆O₃Si	522.723
——	(S)-3-chloro-4-(3-hydroxypyrrolidin-1-yl)-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312755-86-4	C₂₁H₂₆ClN₅O₂Si	444.008
——	(S)-tert-butyl 1-(3-bromo-6-cyano-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrol-4-yl)pyrrolidin-3-yl(ethyl)carbamate	1312755-89-7	C₂₈H₃₉BrN₆O₃Si	615.646
——	(S)-tert-butyl 1-(6-cyano-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrol-4-yl)pyrrolidin-3-yl(ethyl)carbamate	1312754-16-7	C₂₈H₄₀N₆O₃Si	536.75
——	3-chloro-4-(tert-butyl piperazin-1-carboxylate)-9-((2-(trimethylsilyl)ethoxy)methyl)-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carbonitrile	1312756-07-2	C₂₆H₃₅ClN₆O₃Si	543.141