Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.
本文披露了化合物及其药用盐,可用于治疗需要的受试者。本文披露的化合物可能是共济失调-毛细血管扩张和RAD-3相关蛋白激酶(ATR)的
抑制剂。还披露了含有这些化合物或其药用盐的药物组合物,以及其制备和使用方法。