dimethyl sulfosuccinate sodium salt | 50576-97-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: dimethyl sulfosuccinate sodium salt
• 英文别名: sodium dimethyl sulfosuccinate；Sodium dimethylsulfosuccinate；1,2-bis-methoxycarbonyl-ethanesulfonic acid ; sodium-salt；1,2-Bis-methoxycarbonyl-aethansulfonsaeure; Natrium-Salz；Sodium;1,4-dimethoxy-1,4-dioxobutane-2-sulfonate
• CAS: 50576-97-1
• 化学式: C₆H₉O₇S*Na
• 分子量: 248.189
• InChiKey: VDIJONLMYVEURD-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -4.36
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  118
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  dimethyl sulfosuccinate sodium salt 、 (2,4,6-trimethylphenyl)diazonium tetrafluoronorate 以 水 为溶剂， 反应 24.0h， 以160 mg的产率得到
  参考文献：
  名称：

  “捕捉” AOT反胶束的界面：使用化学捕集

  摘要：

  在“捕捉” AOT-2,2,4-三甲基戊烷-水反胶束界面区域中水和磺基琥珀酸酯头基的局部摩尔浓度时，已实现了苯基阳离子捕获技术的首次使用。我们的结果表明，在A0（0.1 M）-2,2,2,4-三甲基戊烷-水反胶束中，磺基琥珀酸酯头基的界面浓度在W0（水与水的摩尔比）中非常高（2.75-2.34 M）表面活性剂）的范围在12至44之间。但是，在相同溶液组成范围内，AOT-2,2,4-三甲基戊烷-水反胶束中水的界面浓度（27.9-32.0 M）显着低于本体摩尔浓度水（55.5 M）。

  DOI：

  10.1002/1521-3765(20000804)6:15<2847::aid-chem2847>3.0.co;2-q
• 作为产物：
  描述：

  马来酸二甲酯 在 sodium hydrogensulfite 作用下， 以 水 为溶剂， 生成 dimethyl sulfosuccinate sodium salt
  参考文献：
  名称：

  琥珀酸盐骨架在 AOT 及其类似分子的无序-有序转变中的作用：通过琥珀酸盐骨架扭转角差异引起的配置的红外吸收光谱检测

  摘要：

  已经详细研究了二烷基磺酸钠（烷基：乙基、正丙基、正丁基、正己基、正庚基、正辛基、正癸基和正十二烷基）和 1,2-双（2-乙基己基）磺基琥珀酸钠（1,2-双（2-乙基己基氧羰基）乙磺酸钠）（AOT ）。结果提供了明确的证据，表明由琥珀酸骨架扭转角的差异引起的两种构型优先稳定在水溶液和固态中，这取决于浓度。因此，该区域的红外光谱可用作阐明 AOT 或其同系物在分子水平上的聚集系统中无序有序转变机制的有力工具。

  DOI：

  10.1246/bcsj.20100002

文献信息

• Raman and IR spectroscopic studies of the interaction between counterion and polar group in self-assembled systems of AOT-homologous “sodium dialkyl sulfosuccinates’'
  作者：Yasuyuki Nagasoe、Naoki Ichiyanagi、Hirofumi Okabayashi、Sandrine Nave、Julian Eastoe、Charmian J. O'Connor

  DOI：10.1039/a904815d

  日期：——

  Headgroup–counterion interactions have been studied for a homologous series of sodium dialkyl sulfosuccinates (SDAS) with propyl, butyl, hexyl, octyl, decyl, undecyl and dodecyl chains as Aerosol-OT analogues. Raman scattering and IR absorption spectra were recorded and compared with those for dimethyl sulfosuccinate monohydrate, diethyl sulfosuccinate trihydrate and diheptyl sulfosuccinate dihydrate, whose crystal structures are known. The spectral features of the C2O and SO3- stretch modes directly reflect the interaction between the polar group and the Na+ ion and depend strongly upon the environment of hydration. The results may be summarized as follows. For the SDAS monohydrates in the solid state, there exists a strong interaction between the β C2O group and the Na+ ion, as a consequence of coordination of the β C2O to the Na+ ion, resulting in splitting of the C2O stretch modes. In particular, the common Raman (IR) bands observed at 1705–1707 (1706–1708) and 1730–1732 (1732–1733) cm-1 may be assigned to the β C2O group coordinated to the Na+ counterion and the hydrated α C2O group, respectively. The extent of splitting of these bands is a measure of the strength of this C2O···Na+ interaction. Coordination of the β C2O to the Na+ ion also affects the C2O deformation modes of the O–C2O linkage. An increased hydration number and longer hydrocarbon chains induce a weak interaction between the C2O group and the Na+ ion. The SO3-···Na+ interaction reflects the SO3- stretch modes, depending upon the extent of hydration. Furthermore, for the SDAS samples in the organic and aqueous microphases, Raman (IR) bands characteristic of the C2O and SO3-1 groups have been used successfully to account for the interaction between the polar group and the Na+ ion.

  头基–对离子相互作用已被研究一系列同系物的硫酸二烷基琥珀酸钠（SDAS），其烷基链包括丙基、丁基、己基、辛基、癸基、十一烷基和十二烷基，作为气溶胶-OT的类似物。记录并比较了拉曼散射和红外吸收光谱，并与已知晶体结构的单水合二甲基琥珀酸、三水合二乙基琥珀酸和二水合二庚基琥珀酸的光谱特征进行了比较。C=O和SO₃⁻的伸缩模式的光谱特征直接反映了极性基团与Na⁺离子之间的相互作用，并且强烈依赖于水合环境。结果可总结如下：在固态的SDAS单水合物中，β C=O基团与Na⁺离子之间存在强相互作用，这是由于β C=O与Na⁺离子的配位，导致C=O伸缩模式的分裂。特别是，在1705–1707 cm⁻¹（1706–1708 cm⁻¹）和1730–1732 cm⁻¹（1732–1733 cm⁻¹）观察到的常见拉曼（红外）特征带可以分别归因于与Na⁺对离子配位的β C=O基团和水合的α C=O基团。这些特征带的分裂程度是C=O· · ·Na⁺相互作用强度的衡量。β C=O与Na⁺离子的配位还影响O–C=O连接的C=O变形模式。增加的水合数和较长的烃链会导致C=O基团与Na⁺离子之间的弱相互作用。SO₃⁻· · ·Na⁺的相互作用反映了SO₃⁻的伸缩模式，依赖于水合程度。此外，对于有机和水相微相中的SDAS样品，C=O和SO₃⁻基团特征的拉曼（红外）特征带已成功用于解释极性基团与Na⁺离子之间的相互作用。
• Thermoplastic resin composition
  申请人：MITSUBISHI CHEMICAL CORPORATION

  公开号：EP0635548A1

  公开（公告）日：1995-01-25

  A thermoplastic resin composition comprising (a) a polyphenylene sulfide resin, (b) a polyphenylene ether resin, (c) a specific organophosphorus compound, and (d) a basic compound is disclosed. The composition exhibits improved compatibility between resinous components (a) and (b) and therefore provides a molded article having high mechanical strength and excellent appearance.

  本发明公开了一种热塑性树脂组合物，该组合物由 (a) 聚苯硫醚树脂、(b) 聚苯醚树脂、(c) 特定有机磷化合物和 (d) 碱性化合物组成。该组合物改善了树脂成分（a）和（b）之间的相容性，从而提供了一种具有高机械强度和出色外观的成型品。
• PROCESS FOR PRODUCTION OF CROSSLINKED POLY(METH)ACRYLIC NITROXIDE COMPOUNDS
  申请人：SUMITOMO SEIKA CHEMICALS CO., LTD.

  公开号：EP1911775A1

  公开（公告）日：2008-04-16

  The present invention relates to a crosslinked poly(meth)acrylic acid nitroxide compound resulting from crosslinking of a poly(meth)acrylic acid nitroxide compound, and an object of the present invention is to provide a method of inexpensively and easily producing a crosslinked poly (meth) acrylic acid nitroxide compound having a high radical concentration. The present invention is a method of producing a crosslinked poly(meth)acrylic acid nitroxide compound including a repeating unit represented by the general formula (2) : (in the formula, R represents a hydrogen atom or a methyl group), comprising a nitroxidation step carried out in a state that a crosslinked poly(meth)acrylic acid imino compound resulting from crosslinking of a poly(meth)acrylic acid imino compound including a repeating unit represented by the general formula (1): (in the formula, R represents the same group as that represented by R in said general formula (2)) is dispersed in water.

  本发明涉及一种由聚(甲基)丙烯酸亚硝基化合物交联产生的交联聚(甲基)丙烯酸亚硝基化合物，本发明的目的是提供一种廉价而简便地生产具有高自由基浓度的交联聚(甲基)丙烯酸亚硝基化合物的方法。 本发明是一种生产交联聚（甲基）丙烯酸亚硝基化合物的方法，该化合物包括通式（2）所代表的重复单元： (式中，R 代表氢原子或甲基），包括在以下状态下进行的硝化步骤：由包括通式 (1) 代表的重复单元的聚(甲基)丙烯酸亚胺化合物交联得到的交联聚(甲基)丙烯酸亚胺化合物： (式中，R 代表与所述通式 (2) 中 R 代表的基团相同的基团）分散在水中。
• Apparatus for histoprocessing of tissue samples
  申请人：THE UNIVERSITY OF MIAMI

  公开号：EP2199774A1

  公开（公告）日：2010-06-23

  Described is an apparatus for rapid processing of tissue specimens for histology with continuous throughput, the apparatus comprising: (a) a microwave unit which (1) fixes, dehydrates, and defats the tissue specimens with a non-aqueous solution In a first vessel; (II) agitates the tissue specimens and the non-aqueous solution In the first vessel; and (III) exposes the tissue specimens and the non-aqueous solution in the first vessel to microwave energy to produce fixed, dehydrated, and defatted tissue specimens; and a source for the nen-aqueous solution which is fluidly coupled to the first vessel; (b) an Impregnator unit which (I) Impregnates the fixed, dehydrated, and defatted tissue specimens with a wax solution In cut second vessel; (ii) agitates the fixed, dehydrated, and defatted tissue specimens and the wax solution In the second vessel; and (iii) exposes the fixed, dehydrated, and defatted tissue specimens and the wax solution to elevated temperature under a vacuum to produce fixed, dehydrated, defatted, and impregnated tissue specimens; and a source for the wax solution which Is fluidly coupled to the second vessel; and wherein tissue specimens are sequentially transferred into the first vessel and then into the second vessel.

  描述了一种用于连续快速处理组织学组织标本的设备，该设备包括 (a) 微波装置：(1) 在第一容器中用非水溶液对组织标本进行固定、脱水和脱脂处理；(2) 在第一容器中搅拌组织标本和非水溶液；(3) 将第一容器中的组织标本和非水溶液暴露于微波能下，以产生固定、脱水和脱脂的组织标本；以及一个与第一容器流体连接的水溶液源； (b) 浸渍器装置，该装置 (I) 在切割的第二容器中用蜡溶液浸渍固定、脱水和脱脂的组织标本；(ii) 在第二容器中搅拌固定、脱水和脱脂的组织标本和蜡溶液；(iii) 将固定的、脱水的和脱脂的组织标本和蜡溶液暴露于真空下的高温，以产生固定的、脱水的、脱脂的和浸渍的组织标本；以及与第二容器流体连接的蜡溶液源；以及 其中组织标本依次转移到第一容器中，然后转移到第二容器中。
• Simultaneous dehydration and staining of tissue for deep imaging
  申请人：APPLIKATE TECHNOLOGIES LLC

  公开号：US10591392B2

  公开（公告）日：2020-03-17

  A biopsy-sized tissue sample is stained for quick imaging. A significant amount of permeation enhancer is included in a mixed solution of permeant enhancer, fixative or dehydrant, and one or two fluorescent dyes to simultaneously dehydrate and dye the tissue sample. The permeation enhancer, e.g., 10% to 50% in the mixed solution, achieves an image of dyed tissue in the contacted tissue sample at a depth of at least 200 um within no more than 1.5 hours. One of the fluorescent dyes is a fluorescent nuclear dye such as DAPI, SYTOX green, acridine orange, propidium iodide, or a Hoechst dye. The other fluorescent dye is a fluorescent protein dye such as eosin or rhodamine B. The tissue sample is cleared with a clearing agent having a refractive index of at least 1.4[R2], e.g., using BABB. The mixed solution may further include Chloroform or other morphology preservative.

  对活检大小的组织样本进行染色，以便快速成像。在渗透增强剂、固定剂或脱水剂以及一种或两种荧光染料的混合溶液中加入大量渗透增强剂，以同时对组织样本进行脱水和染色。渗透促进剂，如在混合溶液中占 10%-50%，可在不超过 1.5 小时的时间内，在接触的组织样本中形成深度至少为 200 微米的染色组织图像。其中一种荧光染料是荧光核染料，如 DAPI、SYTOX 绿、吖啶橙、碘化丙啶或 Hoechst 染料。另一种荧光染料是荧光蛋白染料，如曙红或罗丹明 B。组织样本用折射率至少为 1.4[R2]的透明剂清除，如使用 BABB。混合溶液可进一步包括氯仿或其他形态防腐剂。