2-butoxy-butyric acid | 56674-72-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-butoxy-butyric acid
• 英文别名: 2-Butyloxy-buttersaeure；2-Butoxy-buttersaeure；2-Butoxybutanoic acid
• CAS: 56674-72-7
• 化学式: C₈H₁₆O₃
• 分子量: 160.213
• InChiKey: ZMEAFEGUMLZXBN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-butoxy-butyric acid 生成 3-butyloxy-2-methyl-pentanol-(2)
  参考文献：
  名称：

  Elphimoff, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1947, vol. 224, p. 400

  摘要：

  DOI：
• 作为产物：
  描述：

  2-溴丁酸 、 sodium butanolate 生成 2-butoxy-butyric acid
  参考文献：
  名称：

  Elphimoff, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1947, vol. 224, p. 400

  摘要：

  DOI：

文献信息

• NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT
  申请人：Chen James M.

  公开号：US20100104532A1

  公开（公告）日：2010-04-29

  The invention provides unsaturated phosphonates of Formula I or a tautomer or pharmaceutically accepatble salt thereof, as described herein, as well as pharmaceutical compositions comprising the compounds, and therapeutic methods comprising administering the compounds. The compounds have anti-viral properties and are useful for treating viral infections (e.g. HCV) in animals (e.g. humans).

  本发明提供了公式I或其互变异构体或药学上可接受的盐的不饱和膦酸酯，以及包含这些化合物的制药组合物和包括给予这些化合物的治疗方法。这些化合物具有抗病毒性质，适用于治疗动物（如人类）的病毒感染（例如HCV）。
• Oligomers of 2,2,6,6-tetramethylpiperidinol, polycarboxylic acid esters and synthetic polymer compositions
  申请人：ADEKA ARGUS CHEMICAL CO., Ltd.

  公开号：EP0108993A1

  公开（公告）日：1984-05-23

  Oligomers of 2,2,6,6-tetramethylpiperidinol polycarboxylic acid esters are provided having the formula: wherein: Z is the residue of an aliphatic or aromatic or nitriloaliphatic or hydroxy aliphatic polycarboxylic acid having from three to six carboxylic acid groups and from one to thirty carbon atoms; wherein R3 is hydrogen, alkyl and hydroxyalkyl having from one to about twenty carbon atoms; cycloalkyl having from six to about twenty carbon atoms; aryl having from six to about twenty carbon atoms; or cycloalkylene with the N in the ring and having from two to five carbon atoms; R is alkylene having from two to about twelve carbon atoms; cycloalkylene having from three to about twelve carbon atoms; phenylene having from six to about twenty carbon atoms; mixed alkylenecycloalkylene or alkylene phenylene or oxyalkylene having from two to about twelve carbon atoms; wherein R4 is alkyl having from one to about six carbon atoms; R2 is hydrogen; oxyl; alkyl having from one to about twenty carbon atoms; epoxyalkyl having from two to about six carbon atoms or hydroxyalkyl having from one to about six carbon atoms; acyl having from one to about six carbon atoms; aroyl having from seven to about twenty carbon atoms; and alkaryl having from seven to about twenty carbon atoms; (Continuation next page)

  2,2,6,6-四甲基哌啶醇聚羧酸酯的低聚物具有以下式子： 其中 Z 是具有三至六个羧酸基团和一至三十个碳原子的脂肪族或芳香族或氮脂 族或羟基脂肪族聚羧酸的残余物； 其中 R3 是氢、烷基和羟基烷基，具有一至约二十个碳原子；环烷基，具有六至约二十个碳原子；芳基，具有六至约二十个碳原子；或环亚烷基，N 位于环中，具有二至五个碳原子； R 是具有 2 至约 12 个碳原子的亚烷基；具有 3 至约 12 个碳原子的环亚烷基；具有 6 至约 20 个碳原子的亚苯基；具有 2 至约 12 个碳原子的混合亚烷基环亚烷基或亚苯基或氧烷基； 其中 R4 是具有 1 至约 6 个碳原子的烷基； R2是氢；氧代烷基；具有一至约二十个碳原子的烷基；具有二至约六个碳原子的环氧烷基或具有一至约六个碳原子的羟基烷基；具有一至约六个碳原子的酰基；具有七至约二十个碳原子的芳基；和具有七至约二十个碳原子的烷芳基； (下页接续)
• Verfahren zur Herstellung von Isocyanuratgruppen und olefinische Doppelbindungen aufweisenden Verbindungen, die nach diesem Verfahren erhältlichen Verbindungen und ihre Verwendung als Bindemittel bzw. Bindemittelkomponente in Überzugsmitteln
  申请人：BAYER AG

  公开号：EP0126359A2

  公开（公告）日：1984-11-28

  Ein neues Verfahren zur Herstellung von unter dem Einfluß energiereicher Strahlung vernetzbaren, lsocyanuratgruppen, olefinische Doppelbindungen und gegebenenfalls blokkierte, Isocyanatgruppen aufweisenden Verbindungen durch Umsetzung von (i) gegebenenfalls im Gemisch mit Isocyanuratgruppen-freien, aliphatischen und/oder cycloaliphatischen Polyisocyanaten vorliegenden, aliphatischen und/oder cycloaliphatischen Isocyanato-Isocyanuraten, deren Isocyanatgruppen bis zu 70% mit Blockierungsmittel blockiert sein können, mit (ii) Hydroxylgruppen aufweisenden Estern der Acrylsäure und/oder Methacrylsäure, die gemäß diesem Verfahren erhältlichen, Isocyanuratgruppen aufweisenden Umsetzungsprodukte, sowie ihre Verwendung als Bindemittel bzw. Bindemittelkomponente in, durch den Einfluß energiereicher Strahlung vernetzbaren Überzugsmitteln.

  一种用于制备可在高能辐射影响下交联并具有异氰尿酸酯基团、烯烃双键和可选封端异氰酸酯基团的化合物的新工艺，其方法是：(i)可选与不含异氰酸酯基团的多异氰酸酯混合存在的脂肪族和/或环脂肪族多异氰酸酯，与(ii)异氰酸酯基团最多可被封端剂封端 70%的脂肪族和/或环脂肪族异氰酸酯反应、脂肪族和/或环脂肪族异氰酸酯，其异氰酸酯基团最多可被 70% 的封端剂封端；(ii) 含羟基的丙烯酸和/或甲基丙烯酸酯，通过该工艺可获得含有异氰尿酸酯基团的反应产物，并将其用作不含异氰酸酯的脂肪族和/或环脂肪族多异氰酸酯中的粘合剂或粘合剂组分，或通过该工艺与(iii) 不含异氰酸酯的脂肪族和/或环脂肪族多异氰酸酯结合使用。可在高能辐射影响下交联的涂层组合物中的粘合剂成分。
• Bis(2,2,6,6-tetramethylpiperidyl-1,3,5-triazinyl)-spirodiamines and spiroglycol ethers and synthetic resin compositions containing the same
  申请人：ADEKA ARGUS CHEMICAL CO., Ltd.

  公开号：EP0148962A1

  公开（公告）日：1985-07-24

  Bis(2,2,6,6-tetramethylpiperidyl-1,3,5. triazinyl)spirodiamines and spiroglycol ethers are provided, having the formula: wherein: R1 is selected from the group consisting of hydrogen, alkyl having from one to about eighteen carbon atoms, hydroxyalkyl having from two to about six carbon atoms; epoxyalkyl having from three to about eight carbon atoms; alkylaryl having from seven to about eighteen carbon atoms; acyl having from two about eight carbon atoms; and oxyl; R2 is alkylene having from one to about six carbon atoms; Z is selected from the group consisting of in which R3 is alkyl having from one to about six carbon atoms; and R4 is selected from the group consisting of hydrogen; alkyl having from one to about eighteen carbon atoms; cycloalkyl having from about four to about eight carbon atoms; hydroxy alkyl and alkoxyalkyl having from two to about twelve carbon atoms and dialkylamino having from two to about ten carbon atoms; X is selected from the group consisting of -O-. and in which R5 is selected from the group consisting of hydrogen, alkyl having from one to about eighteen carbon atoms; cycloalkyl having from about four to about eight carbon atoms; hydroxy alkyl and alkoxyalkyl having from two to about twelve carbon atoms, and dialkylamino having from two to about ten carbon atoms; and Y is selected from the group consisting of: and CI; in which R6 is selected from the group consisting of alkyl having from one to about eighteen carbon atoms; cycloalkyl having from about four to about eight carbon atoms; hydroxy alkyl and alkoxyalkyl having from two to about twelve carbon atoms and dialkylamino having from two to about ten carbon atoms and aryl and alkaryl having from six to about twenty-four carbon atoms; R7 and Ra are selected from the group consisting of hydrogen, alkyl having from one to about eighteen carbon atoms; and alkylene forming a heterocyclic ring including the nitrogen atom in the ring and having from four to seven carbon atoms and no or one oxygen atom; and n is a number from 1 to about 50, preferably from 1 to about 5, representing the average number of units enclosed by the brackets; and synthetic resin compositions containing the same as light stabilizers.

  提供了双(2,2,6,6-四甲基哌啶基-1,3,5. 三嗪基)螺二胺和螺环乙二醇醚，它们具有以下式子： 其中 R1 选自氢、具有 1 至约 18 个碳原子的烷基、具有 2 至约 6 个碳原子的羟基烷基、具有 3 至约 8 个碳原子的环氧烷基、具有 7 至约 18 个碳原子的烷基芳基、具有 2 至约 8 个碳原子的酰基和羰基组成的组； R2 是具有 1 至约 6 个碳原子的亚烷基； Z 选自以下组成的组 其中 R3 是具有 1 至约 6 个碳原子的烷基；和 R4 选自由氢、1 至 18 个碳原子的烷基、4 至 8 个碳原子的环烷基、2 至 12 个碳原子的羟基烷基和烷氧基烷基以及 2 至 10 个碳原子的二烷基氨基组成的组； X选自由-O-组成的组。 其中 R5 选自由氢、具有 1 至约 18 个碳原子的烷基、具有约 4 至约 8 个碳原子的环烷基、具有 2 至约 12 个碳原子的羟基烷基和烷氧基烷基以及具有 2 至约 10 个碳原子的二烷基氨基组成的组；以及 Y 选自以下组成的组 和 CI； 其中 R6 选自由 1 至约 18 个碳原子的烷基、约 4 至约 8 个碳原子的环烷基、2 至约 12 个碳原子的羟基烷基和烷氧基烷基、2 至约 10 个碳原子的二烷基氨基以及 6 至约 24 个碳原子的芳基和烷芳基组成的组； R7 和 Ra 选自由氢、具有 1 至约 18 个碳原子的烷基和形成杂环（包括环中的氮原子）的亚烷基（具有 4 至 7 个碳原子，没有或仅有一个氧原子）组成的组；以及 n 是 1 至约 50 的数字，最好是 1 至约 5 的数字，代表括号内单位的平均数量；以及含有相同的光稳定剂的合成树脂组合物。
• Alkylidene bisphenol phosphites and phosphates having 2,2,6,6-tetramethyl piperidinyl groups and synthetic resin compositions
  申请人：ADEKA ARGUS CHEMICAL CO., Ltd.

  公开号：EP0149259A2

  公开（公告）日：1985-07-24

  Alkylidene bisphenol phosphites and phosphates having 2,2,6,6-tetramethyl piperidinyl groups are provided having the formula: wherein: R, is alkyl having from one to about twelve carbon atoms; R2, R3 and R4 are each selected from the group consisting of hydrogen and alkyl having from one to about twelve carbon atoms; m is 0 or 1; n is 0 or 1; X is selected from the group consisting of wherein: R5 is selected from the group consisting of hydrogen oxyl O, alkyl having from one to about twelve carbon atoms; aryl alkyl having from seven to about eighteen carbon atoms: 2,3-epoxypropyl, acyl having from one to about eight carbon atoms and in which Rs is selected from the group consisting of hydrogen, alkyl having from one to about twelve carbon atoms and phenyl, and Y, is selected from the group consisting of hydrogen; acyl having from one to about twelve carbon atoms; and Z, is selected from the group consisting of -CH and wherein R7 is alkyl having from one to about twelve carbon atoms: and wherein: R6 is selected from the group consisting of hydrogen, alkyl having from one to about twelve carbon atoms and phenyl; and Z2 is selected from the group consisting of >C=O; -CH-O-Y2; in which R7 is alkyl having from one to about twelve carbon atoms; R8 is alkylene having from one to about eight carbon atoms and Y2 is selected from the group consisting of hydrogen and acyl having from one to about eight carbon atoms.

  提供了具有 2，2，6，6-四甲基哌啶基团的亚烷基双酚亚磷酸酯和磷酸酯，其结构式为 其中 R是具有1至约12个碳原子的烷基； R2、R3 和 R4 分别选自由一个至约十二个碳原子的氢和烷基组成的组； m为0或1 n 为 0 或 1； X 选自以下组成的组 其中 R5 选自由氢氧 O、具有 1 至约 12 个碳原子的烷基、具有 7 至约 18 个碳原子的芳基烷基组成的组：2,3-环氧丙基，具有 1 至 8 个碳原子的酰基，以及 其中 Rs 选自氢、具有 1 至约 12 个碳原子的烷基和苯基组成的组，Y 选自氢、具有 1 至约 12 个碳原子的酰基组成的组，以及 Z，选自由-CH 和-CH烷基组成的组。 其中 R7 是具有 1 至约 12 个碳原子的烷基：和 其中 R6 选自由氢、具有 1 至 12 个碳原子的烷基和苯基组成的组；以及 Z2 选自由 >C=O；-CH-O-Y2 组成的组； 其中 R7 是具有 1 至约 12 个碳原子的烷基；R8 是具有 1 至约 8 个碳原子的亚烷基；Y2 选自氢和具有 1 至约 8 个碳原子的酰基组成的组。