docosan-2-ol | 83209-64-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: docosan-2-ol
• 英文别名: 2-Docosanol
• CAS: 83209-64-7
• 化学式: C₂₂H₄₆O
• 分子量: 326.607
• InChiKey: MWCUCWLKNRBDOG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.5
• 重原子数：
  23
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  docosan-2-ol 以1%的产率得到
  参考文献：
  名称：

  GREENAWAY, W.;WOLLENWEBER, E.;SCAYSBROOK, T.;WHATLEY, F. R., J. CHROMATOGR., 448,(1988) N 2, C. 284-290

  摘要：

  DOI：
• 作为产物：
  描述：

  docosan-2-one 在 lithium aluminium tetrahydride 、 乙醚 作用下， 生成 docosan-2-ol
  参考文献：
  名称：

  Baykut; Oezeris, Istanbul Universitesi Fen Fakultesi Mecmuasi, Seri C: [Astronomi-Fizik-Kimya], 1957, vol. 22, p. 32,34,35

  摘要：

  DOI：

文献信息

• Hybrid onium salt
  申请人：Ishihara Masami

  公开号：US20050020710A1

  公开（公告）日：2005-01-27

  The present invention relates to a hybrid type onium salt having an iodonium salt and a sulfonium salt in the molecule, useful, for example, as a cationic type photopolymerization initiator and an acid generator for a chemically amplified resist and provides a hybrid type onium salt shown by the general formula [1]: [wherein R 1 to R 3 are each independently a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group or an amino group which maybe substituted; Q 1 is a direct-linkage, an oxygen atom, a sulfur atom or a lower alkylene chain; T 1 is an alkylene group or an arylene group, which may have a substituent selected from the group consisting of a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group and an amino group which may be substituted; and R 4 is an alkyl group, an alkenyl group, an aryl group or an aralkyl group, which may have a substituent selected from the group consisting of a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group and an amino group which may be substituted or a group shown by the general formula [2]: (wherein R 5 to R 7 are each independently a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group or an amino group which maybe substituted; Q 2 is a direct-linkage, an oxygen atom, a sulfur atom or a lower alkylene chain; T 2 an alkylene group or an arylene group, which may have a substituent selected from the group consisting of a halogen atom, an alkyl group, a haloalkyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group and an amino group which may be substituted; A 3 is a counter anion; m is an integer of 0 to 4; and two ns are each independently an integer of 0 to 5); A 1 and A 2 are each independently a counter anion; and m and n are the same as described above], and a polymerization initiator or an acid generator, comprising said onium salt.

  本发明涉及一种杂化型离子盐，其分子中具有碘化离子盐和亚砜盐，例如，作为阳离子型光聚合引发剂和化学放大型抗蚀剂的酸发生剂有用，并提供由通式[1]所示的杂化型离子盐：[其中R1至R3分别独立地是卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基或氨基，可被取代；Q1是直链、氧原子、硫原子或较低的烷基链；T1是烷基或芳基，可具有从卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基和可被取代的氨基中选择的取代基；R4是烷基、烯丙基、芳基或芳基烷基，可具有从卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基和可被取代的氨基中选择的取代基或由通式[2]所示的基：（其中R5至R7分别独立地是卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基或氨基，可被取代；Q2是直链、氧原子、硫原子或较低的烷基链；T2是烷基或芳基，可具有从卤素原子、烷基、卤代烷基、芳基、烷氧基、芳氧基、烷硫基、芳硫基和可被取代的氨基中选择的取代基；A3是一个对离子；m是0到4的整数；两个n各自独立地是0到5的整数）；A1和A2各自独立地是一个对离子；m和n与上述描述相同]，以及包含该离子盐的聚合引发剂或酸发生剂。
• Hemorrhoid treatment pad
  申请人：The Procter and Gamble Company

  公开号：EP2085099A1

  公开（公告）日：2009-08-05

  A hemorrhoid treatment pad, the hemorrhoid treatment pad having a substance on a body facing surface thereof, the substance comprising a skin care composition. The skin care composition can have from about 0.001% to about 0.1% by weight of hexamidine; from about 0.001% to about 10% by weight of zinc oxide; from about 0.01% to about 10% by weight of niacinamide; and a carrier.

  一种痔疮治疗垫，该痔疮治疗垫在其面向身体的表面上有一种物质，该物质包括一种护肤组合物。护肤组合物可以有约 0.001%至约 0.1%（按重量计）的己脒；约 0.001%至约 10%（按重量计）的氧化锌；约 0.01%至约 10%（按重量计）的烟酰胺；以及载体。
• Sanitary napkins with hydrophobic lotions
  申请人：The Procter and Gamble Company

  公开号：EP2103315A2

  公开（公告）日：2009-09-23

  A catamenial device, said device comprising: a topsheet having a body facing surface, wherein said topsheet has a level of hydrophobicity, a lotion composition applied to at least a portion of at least to the body facing surface of said topsheet, said lotion having a level of hydrophobicity equal or greater than that of said topsheet, said lotion composition comprising from about 60% to about 99.9% by weight of the carrier wherein the carrier is selected from the group consisting of petroleum-based hydrocarbons having from about 4 to about 32 carbon atoms, fatty alcohols having from about 12 to about 24 carbon atoms, lower alcohols having from about 1 to about 6 carbon atoms, low molecular weight glycols and polyols, lanolin, and mixtures thereof; a backsheet joined to said topsheet; and an absorbent core disposed between said topsheet and said backsheet.

  一种导尿装置，所述装置包括：具有面向身体表面的表皮，其中所述表皮具有一定的疏水性；涂抹在所述表皮面向身体表面的至少一部分上的乳液组合物，所述乳液的疏水性等于或大于所述表皮的疏水性，所述乳液组合物包括约 60% 至约 99.9%（重量）的载体，其中所述载体选自由以下组成的组：具有约4至约32个碳原子的石油基碳氢化合物、具有约12至约24个碳原子的脂肪醇、具有约1至约6个碳原子的低级醇、低分子量乙二醇和多元醇、羊毛脂，以及它们的混合物；与所述表皮连接的背板；以及设置在所述表皮和所述背板之间的吸收芯。
• METHOD FOR PRODUCING OLIGONUCLEOTIDE
  申请人：Ajinomoto Co., Inc.

  公开号：EP2711370A1

  公开（公告）日：2014-03-26

  The problem of the present invention is provision of a method of producing an n+p-mer oligonucleotide efficiently in a high yield, which includes use of, as a starting material, an n-mer oligonucleotide wherein the 3'-terminal hydroxyl group is protected, and the 5'-terminal hydroxyl group is protected by a temporary protecting group, and continuously performing, in a solution, (1) a deprotection step of the 5'-terminal hydroxyl group, (2) a 5'-terminal elongation step by the addition of a p-mer oligonucleotide wherein the 3'-position is phosphoramidited, and (3) an oxidation step or a sulfurization step of a phosphite triester moiety. It has been found that the above-mentioned problem can be solved by adding a particular cation scavenger during the deprotection step, applying a neutralization treatment after completion of the deprotection reaction, and using a particular oxidizing agent or sulfurizing agent in the oxidation step or sulfurization step.

  本发明的问题是提供一种高产率高效生产 n+p-mer 寡核苷酸的方法，该方法包括使用 n-mer 寡核苷酸作为起始材料，其中 3'末端羟基受到保护，5'末端羟基受到临时保护基团的保护、在溶液中连续进行以下步骤：(1) 5'末端羟基的去保护步骤；(2) 通过添加 p-聚合寡核苷酸进行 5'末端延伸步骤，其中 3'位被磷酸化；(3) 亚磷酸三酯分子的氧化步骤或硫化步骤。 研究发现，在脱保护步骤中加入特定的阳离子清除剂，在脱保护反应完成后进行中和处理，以及在氧化步骤或硫化步骤中使用特定的氧化剂或硫化剂，可以解决上述问题。
• Fast drying coatings
  申请人：——

  公开号：US20040143031A1

  公开（公告）日：2004-07-22

  Novel, rapidly drying, low volatile organic compound (VOC), minimal dot gain coatings, (including lithographic ink and varnish systems) are herein described. These systems dry sufficiently rapidly, that their usage eliminates ink drying speed as the rate limiting factor in most lithographic printing applications. In addition to providing enhanced drying rates as compared with their conventional counterparts, the rapid drying, low/no VOC lithographic coating systems of the instant invention can provide the user with significant improvement in dried film rub resistance.

  本文描述了新型、快速干燥、低挥发性有机化合物 (VOC)、网点增大最小的涂料（包括平版印刷油墨和光油系统）。这些体系的干燥速度非常快，因此在大多数平版印刷应用中，它们的使用消除了油墨干燥速度这一限制因素。与传统的同类产品相比，本发明的快速干燥、低/无挥发性有机化合物平版印刷涂料体系不仅能提高干燥速度，还能显著改善干膜的耐摩擦性。