1,5-diphenylpentasulfane | 100079-88-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,5-diphenylpentasulfane
• 英文别名: diphenyl pentasulfide；phenyl pentasulfide；Diphenylpentasulfane；(phenylpentasulfanyl)benzene
• CAS: 100079-88-7
• 化学式: C₁₂H₁₀S₅
• 分子量: 314.541
• InChiKey: MRYDYPUNTUIQAD-UHFFFAOYSA-N

物化性质

• 沸点：
  475.4±28.0 °C(Predicted)
• 密度：
  1.42±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  127
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  二苯二硫醚 在 Rh(H)(PEt₃)₃ 1,2,3,4,5,6,7,8-八硫杂环辛烷 、 顺-1,2-双(二苯基膦)乙烯 作用下， 以 丙酮 为溶剂， 反应 0.08h， 以0.132 mmol的产率得到diphenyl trisulfide
  参考文献：
  名称：

  铑催化的有机多硫化物与硫之间的硫原子交换反应

  摘要：

  RhH的（PPH 3）4和CIS -1,2-双（二苯基膦基）乙烯（dppv）催化硫和有机多硫化物之间的硫原子的交换。三烷基二硫化物与硫的交换在室温下于5分钟内高效进行，从而产生有机多硫化物的混合物。

  DOI：

  10.1016/j.tetlet.2005.05.024

文献信息

• COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HYPOXIC OR ISCHEMIC INJURY
  申请人：Wintner Edward A.

  公开号：US20100130555A1

  公开（公告）日：2010-05-27

  A method for treating or preventing injury of a biological material exposed to hypoxic or ischemic conditions comprising contacting the biological material with an effective amount of a compound is disclosed. The compound has the following structure (I): R 1 —(S) n —R 2 (I) or a stereoisomer, pharmaceutically acceptable salt or prodrug thereof, wherein R 1 , R 2 , and n are as defined herein. Compounds, methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
• US4303765A
  申请人：——

  公开号：US4303765A

  公开（公告）日：1981-12-01
• US8202997B2
  申请人：——

  公开号：US8202997B2

  公开（公告）日：2012-06-19
• [EN] COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HYPOXIC OR ISCHEMIC INJURY<br/>[FR] COMPOSITIONS ET PROCÉDÉS POUR TRAITER OU PRÉVENIR UNE LÉSION HYPOXIQUE OU ISCHÉMIQUE
  申请人：IKARIA INC

  公开号：WO2010045582A2

  公开（公告）日：2010-04-22

  A method for treating or preventing injury of a biological material exposed to hypoxic or ischemic conditions comprising contacting the biological material with an effective amount of a compound is disclosed. The compound has the following structure (I): R1_(S)n-R2 or a stereoisomer, pharmaceutically acceptable salt or prodrug thereof, wherein R1, R2, and n are as defined herein. Compounds, methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
• Rhodium-catalyzed sulfur atom exchange reaction between organic polysulfides and sulfur
  作者：Mieko Arisawa、Ken Tanaka、Masahiko Yamaguchi

  DOI：10.1016/j.tetlet.2005.05.024

  日期：2005.7

  RhH(PPh3)4 and cis-1,2-bis(diphenylphosphino)ethylene (dppv) catalyze the exchange of sulfur atoms between sulfur and organic polysulfides. The exchange of dialkyl trisulfides with sulfur proceeds at a high efficiency within 5 min at room temperature yielding a mixture of organic polysulfides.

  RhH的（PPH 3）4和CIS -1,2-双（二苯基膦基）乙烯（dppv）催化硫和有机多硫化物之间的硫原子的交换。三烷基二硫化物与硫的交换在室温下于5分钟内高效进行，从而产生有机多硫化物的混合物。