N-Butyl-chlor-methansulfonsaeureamid | 88512-80-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: N-Butyl-chlor-methansulfonsaeureamid
• 英文别名: N-butyl-1-chloromethanesulfonamide
• CAS: 88512-80-5
• 化学式: C₅H₁₂ClNO₂S
• 分子量: 185.675
• InChiKey: LEATUIINEURODU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  54.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  氯甲磺酰氯 生成 N-Butyl-chlor-methansulfonsaeureamid
  参考文献：
  名称：

  TAMARU, MASATOSHI;OGAWA, HARUKI;NISHIMURA, TASIMUMI;TAKAHASHI, YOSHIMASA;+, J. PESTIC. SCI., 13,(1988) N 1, 1-6

  摘要：

  DOI：

文献信息

• El-Hewehi,Z.; Runge,F., Journal fur praktische Chemie (Leipzig 1954), 1962, vol. 16, p. 297 - 336
  作者：El-Hewehi,Z.、Runge,F.

  DOI：——

  日期：——
• TAMARU, MASATOSHI;OGAWA, HARUKI;NISHIMURA, TASIMUMI;TAKAHASHI, YOSHIMASA;+, J. PESTIC. SCI., 13,(1988) N 1, 1-6
  作者：TAMARU, MASATOSHI、OGAWA, HARUKI、NISHIMURA, TASIMUMI、TAKAHASHI, YOSHIMASA、+

  DOI：——

  日期：——
• [EN] SUBSTITUTED THIAZOLIDINEDIONE INDAZOLES, INDOLES AND BENZOTRIAZOLES AS ESTROGEN-RELATED RECEPTOR-a MODULATORS<br/>[FR] THIAZOLIDINEDIONE INDAZOLES, INDOLES ET BENZOTRIAZOLES SUBSTITUÉS UTILES EN TANT QUE MODULATEURS DES RÉCEPTEURS ? LIÉS AUX OESTROGÈNES
  申请人：JANSSEN PHARMACEUTICA NV

  公开号：WO2011149841A1

  公开（公告）日：2011-12-01

  The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating a condition including but not limited to ankylosing spondylitis, artherosclerosis, arthritis (such as rheumatoid arthritis, infectious arthritis, childhood arthritis, psoriatic arthritis, reactive arthritis), bone-related diseases (including those related to bone formation), breast cancer (including those unresponsive to anti-estrogen therapy), cardiovascular disorders, cartilage-related disease (such as cartilage injury/loss, cartilage degeneration, and those related to cartilage formation), chondrodysplasia, chondrosarcoma, chronic back injury, chronic bronchitis, chronic inflammatory airway disease, chronic obstructive pulmonary disease, diabetes, disorders of energy homeostasis, gout, pseudogout, lipid disorders, metabolic syndrome, multiple myeloma, obesity, osteoarthritis, osteogenesis imperfecta, osteolytic bone metastasis, osteomalacia, osteoporosis, Paget's disease, periodontal disease, polymyalgia rheumatica, Reiter's syndrome, repetitive stress injury, hyperglycemia, elevated blood glucose level, and insulin resistance.