2,3,4,5,6-Pentafluor-ω-nitro-styrol | 885-31-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,3,4,5,6-Pentafluor-ω-nitro-styrol
• 英文别名: 2,3,4,5,6-Pentafluor-β-nitro-styrol；1,2,3,4,5-pentafluoro-6-(2-nitroethenyl)benzene
• CAS: 885-31-4
• 化学式: C₈H₂F₅NO₂
• 分子量: 239.101
• InChiKey: LBBACRWAXVCTNR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  45.8
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  2,3,4,5,6-Pentafluor-ω-nitro-styrol 、 N-<(2-Methylphenyl)methylene>-1,1-dimethylethanamine 在 2,2,6,6-四甲基哌啶 、 N-溴代丁二酰亚胺(NBS) 、 正丁基锂 、 过氧化苯甲酰 作用下， 以 四氢呋喃 、 正己烷 、 1,2-二氯乙烷 为溶剂， 反应 14.0h， 生成
  参考文献：
  名称：

  Regiospecific Synthesis of Novel Cyclic Nitrostyrenes and 3-Substituted 2-Nitronaphthalenes

  摘要：

  A two-step, practical, regiospecific, and readily scalable benzannulation protocol for the preparation of novel 3-alkyl- and 3-aryl-substituted 2-nitronaphthalenes is disclosed. Addition of a beta-nitrostyrene or nitroalkene to a solution of freshly prepared lithiated o-tolualdehyde tert-butyl imine first leads to the formation of a nitronate, via rapid 1,4-addition, then an intramolecular aza-Henry reaction takes place to afford a six-membered carbocycle. Subsequent treatment of the reaction mixture with aqueous acid affords novel substituted cyclic nitrostyrenes that can be conveniently aromatized via a one-pot radical-induced bromination and elimination sequence to furnish the corresponding 3-alkyl- or 3-aryl-2-nitronaphthalenes in excellent yields. The straightforward syntheses of 2-aminonaphthalenes, substituted BINAMs, 2-naphthols as well as tricyclic fused 1,2,3-triazoles are also described.

  DOI：

  10.1055/s-0033-1338867
• 作为产物：
  描述：

  2,3,5,6-五氟-alpha-(硝基甲基)苄醇 在 phosphorus pentoxide 作用下， 生成 2,3,4,5,6-Pentafluor-ω-nitro-styrol
  参考文献：
  名称：

  Petrov,V.P. et al., Doklady Chemistry, 1968, vol. 178, p. 113 - 115

  摘要：

  DOI：

文献信息

• A Base-Catalysed One-Pot Three-Component Coupling Reaction Leading to Nitrosubstituted Pyrroles
  作者：Steven Ley、Ian Baxendale、Christopher Buckle、Lucia Tamborini

  DOI：10.1055/s-0028-1087991

  日期：——

  Tosyl isocyanide and ethyl chloroformate react with nitrostyrenes to afford nitro-substituted pyrroles in good yield when a catch-and-release protocol was employed as a purification strategy.

  在采用捕获-释放策略作为纯化方案的情况下，甲磺酰异氰和氯甲酸乙酯与硝基苯乙烯反应，以良好产率得到硝基取代的吡咯。
• Pd/C-Catalyzed Dehydrogenative [3+2] Cycloaddition for the Synthesis of Functionalized Tropanes
  作者：Hai-Jun Wang、Lei Guo、Cheng-Feng Zhu、Yun-Fei Luo、You-Gui Li、Xiang Wu

  DOI：10.1002/ejoc.201801147

  日期：2018.10.24

  Described is a Pd/C‐catalyzed dehydrogenative [3+2] cycloaddition for the synthesis of benzo‐fused tropanes. The reaction proceeds through a sequential Pd/C‐catalyzed dehydrogenative formation of azomethine ylides from amines and 1,3‐dipolar cycloaddition.

  描述了Pd / C催化的脱氢[3 + 2]环加成反应，用于合成苯并熔合的托烷。该反应通过胺的1,3-偶极环加成反应依次进行Pd / C催化的偶氮甲亚胺脱氢反应形成。
• Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition
  申请人：BREWER SCIENCE, INC.

  公开号：US20030054117A1

  公开（公告）日：2003-03-20

  An improved method for applying polymeric antireflective coatings to substrate surfaces and the resulting precursor structures are provided. Broadly, the methods comprise plasma enhanced chemical vapor depositing (PECVD) a polymer on the substrate surfaces. The most preferred starting monomers are 4-fluorostyrene, 2,3,4,5,6-pentafluorostyrene, and allylpentafluorobenzene. The PECVD processes comprise subjecting the monomers to sufficient electric current and pressure so as to cause the monomers to sublime to form a vapor which is then changed to the plasma state by application of an electric current. The vaporized monomers are subsequently polymerized onto a substrate surface in a deposition chamber. The inventive methods are useful for providing highly conformal antireflective coatings on large surface substrates having super submicron (0.25 &mgr;m or smaller) features. The process provides a much faster deposition rate than conventional chemical vapor deposition (CVD) methods, is environmentally friendly, and is economical.

  本发明提供了一种改进的方法，可将聚合物抗反射涂层应用于基底表面及由此产生的前驱体结构。概括地说，该方法包括在基底表面进行等离子体增强化学气相沉积（PECVD）聚合物。最优选的起始单体是 4-氟苯乙烯、2,3,4,5,6-五氟苯乙烯和烯丙基五氟苯。PECVD 工艺包括将单体置于足够的电流和压力下，使单体升华形成蒸汽，然后通过施加电流将蒸汽转变为等离子状态。气化的单体随后在沉积室中聚合到基底表面上。本发明的方法适用于在具有超亚微米（0.25 微米或更小）特征的大表面基底上提供高保形防反射涂层。与传统的化学气相沉积（CVD）方法相比，该工艺的沉积速率快得多，而且环保、经济。
• EP1397260A4
  申请人：——

  公开号：EP1397260A4

  公开（公告）日：2006-03-08
• POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION
  申请人：Brewer Science, Inc.

  公开号：EP1397260A1

  公开（公告）日：2004-03-17