2-Hydroxy-1,3-dimethyl-cyclobuten-(1)-on-(4) | 20117-50-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 乙烯基酸
• 英文名称: 2-Hydroxy-1,3-dimethyl-cyclobuten-(1)-on-(4)
• 英文别名: 1,3-Dimethyl-cyclobuten-(1)-ol-(2)-on-(4)；3-Hydroxy-2,4-dimethyl-cyclobut-2-enon；3-Hydroxy-2,4-dimethylcyclobut-2-enon；1.3-Dimethyl-cyclobut-1-en-2-ol-4-on；1,3-Dimethylcyclobut-1-en-2-ol-4-on；3-Hydroxy-2,4-dimethylcyclobutenon；2-Cyclobutenone, 3-hydroxy-2,4-dimethyl-；3-hydroxy-2,4-dimethylcyclobut-2-en-1-one
• CAS: 20117-50-4
• 化学式: C₆H₈O₂
• 分子量: 112.128
• InChiKey: ZSADIOZWRMCYNY-UHFFFAOYSA-N

物化性质

• 熔点：
  138 °C
• 沸点：
  196.2±40.0 °C(Predicted)
• 密度：
  1.196±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-Hydroxy-1,3-dimethyl-cyclobuten-(1)-on-(4) 在 溴 作用下， 以 四氯化碳 、 乙醚 为溶剂， 生成 3-Brom-2-methoxy-1,3-dimethyl-cyclobuten-(1)-on-(4)
  参考文献：
  名称：

  Lewis Acid Induced Rapid Allylic Rearrangements of 2-Halo-3-hydroxy-2,4-dimethylcyclobutenones. An Unusually Reactive α-Haloketone

  摘要：

  DOI：

  10.1021/ja01058a026
• 作为产物：
  描述：

  1,3-Dimethyl-cyclobuten-(1)-ol-(2)-on-(4)-propionat, trimeres Methylketen 生成 2-Hydroxy-1,3-dimethyl-cyclobuten-(1)-on-(4)
  参考文献：
  名称：

  Enk,E.; Spes,H., Angewandte Chemie, 1961, vol. 73, p. 334 - 338

  摘要：

  DOI：

文献信息

• CYANINE COMPOUNDS AND THEIR USE IN STAINING BIOLOGICAL SAMPLES
  申请人：Shao Jianhui

  公开号：US20100112584A1

  公开（公告）日：2010-05-06

  Cyanine compounds having the general formula I for staining biological samples, wherein R 1 , R 2 , X, Y, A 1 and A 2 are as defined in the specification. These kinds of compounds may show good light illumination stability, have a maximum absorption peak around 640 nm that may not change as a function of ambient temperature, have rapidly increased fluorescence intensity upon binding to nucleic acids to form compound/nucleic acid complexes, and have a light spectrum in the near-infrared region, thereby effectively reducing interference from background fluorescence and increasing the accuracy of the detection when used as a staining agent for nucleic acids in a flow cytometer. The compounds provided can be used as a staining agent for erythroblasts in the blood.
• REAGENT FOR BLOOD ANALYSIS AND METHOD OF USING THE SAME
  申请人：Baohua Zhang

  公开号：US20100143955A1

  公开（公告）日：2010-06-10

  A reagent for blood analysis includes: (1) a compound having the general formula I; and (2) at least one surfactant selected from cationic surfactants and nonionic surfactants. In another aspect a method for differentiating and counting blood cells is provided, the method includes the following steps: (a) mixing a blood sample with the reagent for blood analysis according to the present disclosure to form a cell suspension; (b) detecting scattered light signals and fluorescence signals of cells in the blood sample; and (c) differentiating and counting the cells in the blood sample based upon the scattered light signals and fluorescence signals. The reagent for blood analysis may be effective for identifying and counting erythroblasts and/or basophils in a blood sample to be detected, and meanwhile counting leukocytes therein.
• US8334109B2
  申请人：——

  公开号：US8334109B2

  公开（公告）日：2012-12-18
• US8383830B2
  申请人：——

  公开号：US8383830B2

  公开（公告）日：2013-02-26
• Enk,E.; Spes,H., Angewandte Chemie, 1961, vol. 73, p. 334 - 338
  作者：Enk,E.、Spes,H.

  DOI：——

  日期：——