trans-2-decenoic acid butyl ester | 7492-45-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: trans-2-decenoic acid butyl ester
• 英文别名: Butyl 2-decenoate；butyl (E)-dec-2-enoate
• CAS: 7492-45-7；343616-49-9
• 化学式: C₁₄H₂₆O₂
• 分子量: 226.359
• InChiKey: DTCZJIDFDTTXSG-VAWYXSNFSA-N

物化性质

• 沸点：
  291.2±9.0 °C(Predicted)
• 密度：
  0.881±0.06 g/cm3(Predicted)
• LogP：
  6.10
• 物理描述：
  Colourless liquid; Powerful, fatty, fruity aroma
• 溶解度：
  Soluble in most fixed oils; Insoluble in water
• 折光率：
  1.444-1.451

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  16
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-壬炔 、 一氧化碳 、 正丁醇 在 palladium diacetate 、 1,4-双(二苯基膦)丁烷 作用下， 以 二氯甲烷 为溶剂， 110.0 ℃ 、4.14 MPa 条件下， 反应 20.0h， 生成 trans-2-decenoic acid butyl ester 、 Butyl 2-methylidenenonanoate
  参考文献：
  名称：

  Pd（II）-dppb和合成气在中性条件下催化末端炔烃的区域选择性加氢酯化

  摘要：

  在中性条件下，钯（II）在合成气中区域选择性地催化末端炔烃的加氢酯化反应，形成出色的化学收率的α，β-不饱和酯3和4。通过在包括CH 2 Cl 2的溶剂中包含Pd（II），1,4-双（二苯基膦基）丁烷（dppb）和CO / H 2的催化体系获得对线性酯4的高选择性。区域选择性的控制在很大程度上取决于配体的类型，溶剂和合成气混合物的使用。

  DOI：

  10.1016/s0040-4039(01)00152-6

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• PDK4 INHIBITOR AND USE THEREOF
  申请人：THE KITASATO INSTITUE

  公开号：US20150344404A1

  公开（公告）日：2015-12-03

  The present invention to provide a novel pyruvate dehydrogenase kinase inhibitors. A pyruvate dehydrogenase kinase inhibitor comprising a compound represented by the general formula (I) as an active ingredient (wherein, ring A represents a 6-membered aromatic hydrocarbon ring optionally substituted with 2-4 substituents, R 1 and R 4 , which are the same or different, represent a hydrogen atom, a hydroxyl group, an optionally substituted C1-6 alkyl group, R 2 and R 3 , which are the same or different, represent a hydrogen atom, a carboxyl group, an optionally substituted C1-6 alkyl group, an optionally substituted C6-10 aryl group, or a group represented by —C (═R 9 )—R 10 ), a pharmaceutical composition for treatment or prophylaxis of diseases or disorders that pyruvate dehydrogenase kinase relates to its development or aggravation, and a cosmetic composition, and the like.

  本发明提供了一种新型丙酮酸脱氢酶激酶抑制剂。一种丙酮酸脱氢酶激酶抑制剂包括一种以通式(I)表示的化合物作为活性成分（其中，环A代表一个6-成员芳香碳氢环，可选择地取代有2-4个取代基，R1和R4，它们相同或不同，代表氢原子，羟基，可选择地取代的C1-6烷基基团，R2和R3，它们相同或不同，代表氢原子，羧基，可选择地取代的C1-6烷基基团，可选择地取代的C6-10芳基基团，或由—C(═R9)—R10表示的基团），一种用于治疗或预防与丙酮酸脱氢酶激酶有关的疾病或紊乱的药物组合物，以及一种化妆品组合物等。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• New chewing gum base and their use in a chewing gum
  申请人：NABISCO BRANDS, Inc.

  公开号：EP0066864A2

  公开（公告）日：1982-12-15

  The present invention is a homogeneous gum base composition which includes a properly plasticized elastomer component and a properly plasticized resin component, and optionally, a third component having fillers, emulsifiers, and/or softening agents, texturizing agents and waxes normally associated with production of chewing gum base. This invention also includes a method of preparing the novel chewing gum base as well as their use in a chewing gum.

  本发明是一种均匀的口香糖胶基组合物，它包括适当塑化的弹性体成分和适当塑化的树脂成分，以及可选的第三种成分，第三种成分具有通常与口香糖胶基生产相关的填料、乳化剂和/或软化剂、质地剂和蜡。本发明还包括制备新型口香糖基料的方法以及它们在口香糖中的用途。
• Reduced-shrink bubble gum and method for preparing same
  申请人：NABISCO BRANDS, Inc.

  公开号：EP0102081A2

  公开（公告）日：1984-03-07

  A reduced-shrink chewing gum composition having good film-forming characteristics which is prepared with an increased amount of inert inorganic filler and a non-styrene butadiene base. The filler material is included as a component of the base and as a component added after formation of the base.

  一种具有良好成膜特性的减缩口香糖组合物，它是用更多的惰性无机填料和非苯乙烯丁二烯基制备而成。填料既可作为基料的成分，也可作为基料形成后添加的成分。