1-Nitro-4-[(2,2,3,3,4,4,5,5,6,6,6-undecafluorohexyl)oxy]benzene | 183997-46-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Nitro-4-[(2,2,3,3,4,4,5,5,6,6,6-undecafluorohexyl)oxy]benzene
• 英文别名: 1-nitro-4-(2,2,3,3,4,4,5,5,6,6,6-undecafluorohexoxy)benzene
• CAS: 183997-46-8
• 化学式: C₁₂H₆F₁₁NO₃
• 分子量: 421.167
• InChiKey: RGOZNZUAXTXBNG-UHFFFAOYSA-N

物化性质

• 沸点：
  294.1±40.0 °C(Predicted)
• 密度：
  1.571±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  55
• 氢给体数：
  0
• 氢受体数：
  14

反应信息

• 作为反应物：
  描述：

  1-Nitro-4-[(2,2,3,3,4,4,5,5,6,6,6-undecafluorohexyl)oxy]benzene 在 盐酸 、 sodium hydroxide 、 sodium carbonate 、 potassium carbonate 、 溶剂黄146 、 potassium iodide 、 tin(ll) chloride 、 sodium nitrite 作用下， 以 乙醇 、 丙酮 为溶剂， 反应 9.0h， 生成 [4-(6-Bromo-hexyloxy)-phenyl]-[4-(2,2,3,3,4,4,5,5,6,6,6-undecafluoro-hexyloxy)-phenyl]-diazene
  参考文献：
  名称：

  Synthesis of 4-(1H,1H-perfluoroalkoxy)-4′-(6-methacryloyloxy-hexyloxy)-azobenzenes and their liquid crystalline intermediates

  摘要：

  The synthesis and characterization of 4-(1H,1H-perfluoroalkoxy)-4'-(6-methacryloyloxy-hexyloxy)-azobenzenes with different lengths of the fluorinated tail group (C-2-C-8) and their liquid crystalline intermediates, starting from 1H,1H-perfluoroalkyl-p-nitrophenyl-ethers is described. The liquid crystalline properties of the compounds were studied by differential scanning calorimetry, polarizing optical microscopy and X-ray diffraction methods. In contrast with their non-fluorinated analogues, all the liquid crystalline products display smectic mesophases caused by the fluorination of the tail group. (C) 1997 Elsevier Science S.A.

  DOI：

  10.1016/s0022-1139(97)00076-6
• 作为产物：
  描述：

  全氟己酸 在 lithium aluminium tetrahydride 、 sodium hydride 、 三乙胺 作用下， 以 六甲基磷酰三胺 、 二氯甲烷 为溶剂， 反应 14.0h， 生成 1-Nitro-4-[(2,2,3,3,4,4,5,5,6,6,6-undecafluorohexyl)oxy]benzene
  参考文献：
  名称：

  Various synthetic approaches to fluoroalkyl p-nitrophenyl ethers

  摘要：

  Homologous 1H,1H-perfluoroalkyl p-nitrophenyl ethers (alkyl = C-2-C-8) were synthesized using different methods. The results are discussed in context with contradictory comments of the literature. The fluoroalkoxylation of p-chloronitrobenzene occurs in only one step, but it is limited to small fluoroalkyl groups. The fluoroalkylation of p-nitrophenol via sulphonic acid esters is a better synthetic route. Differences in reactivity and yield between tosylates, mesylates and triflates are found and discussed. The preferred synthesis includes the use of trifluoromethane sulphonic acid esters.

  DOI：

  10.1016/s0022-1139(96)03490-2

文献信息

• Synthesis of 4-(1H,1H-perfluoroalkoxy)-4′-(6-methacryloyloxy-hexyloxy)-azobenzenes and their liquid crystalline intermediates
  作者：Thomas Thiele、Dietrich Prescher、Ralf Ruhmann、Dietmar Wolff

  DOI：10.1016/s0022-1139(97)00076-6

  日期：1997.10

  The synthesis and characterization of 4-(1H,1H-perfluoroalkoxy)-4'-(6-methacryloyloxy-hexyloxy)-azobenzenes with different lengths of the fluorinated tail group (C-2-C-8) and their liquid crystalline intermediates, starting from 1H,1H-perfluoroalkyl-p-nitrophenyl-ethers is described. The liquid crystalline properties of the compounds were studied by differential scanning calorimetry, polarizing optical microscopy and X-ray diffraction methods. In contrast with their non-fluorinated analogues, all the liquid crystalline products display smectic mesophases caused by the fluorination of the tail group. (C) 1997 Elsevier Science S.A.
• Various synthetic approaches to fluoroalkyl p-nitrophenyl ethers
  作者：Dietrich Prescher、Thomas Thiele、Ralf Ruhmann

  DOI：10.1016/s0022-1139(96)03490-2

  日期：1996.8

  Homologous 1H,1H-perfluoroalkyl p-nitrophenyl ethers (alkyl = C-2-C-8) were synthesized using different methods. The results are discussed in context with contradictory comments of the literature. The fluoroalkoxylation of p-chloronitrobenzene occurs in only one step, but it is limited to small fluoroalkyl groups. The fluoroalkylation of p-nitrophenol via sulphonic acid esters is a better synthetic route. Differences in reactivity and yield between tosylates, mesylates and triflates are found and discussed. The preferred synthesis includes the use of trifluoromethane sulphonic acid esters.