3-O-[[3-[(3-oxo-3-pent-4-ynoxypropanoyl)oxymethyl]phenyl]methyl] 1-O-pent-4-ynyl propanedioate | 1040750-65-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-O-[[3-[(3-oxo-3-pent-4-ynoxypropanoyl)oxymethyl]phenyl]methyl] 1-O-pent-4-ynyl propanedioate
• CAS: 1040750-65-9
• 化学式: C₂₄H₂₆O₈
• 分子量: 442.466
• InChiKey: LWQLFYMVVDMCDR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  32
• 可旋转键数：
  18
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  105
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  3-O-[[3-[(3-oxo-3-pent-4-ynoxypropanoyl)oxymethyl]phenyl]methyl] 1-O-pent-4-ynyl propanedioate 、 足球烯 在 碘 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 甲苯 为溶剂， 以44%的产率得到
  参考文献：
  名称：

  Click chemistry with fullerene derivatives

  摘要：

  C(60) derivatives bearing either terminal alkyne or azide functional groups have been prepared and used as building blocks under the copper-mediated Huisgen 1,3-dipolar cycloaddition conditions leading to 1,2,3-triazole derivatives. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.04.064
• 作为产物：
  描述：

  4-戊炔-1-醇 、 propanedioic acid 1,3-phenylenebis(methylene) 在 4-二甲氨基吡啶 、 1-羟基苯并三唑 、 N,N'-二环己基碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 以58%的产率得到3-O-[[3-[(3-oxo-3-pent-4-ynoxypropanoyl)oxymethyl]phenyl]methyl] 1-O-pent-4-ynyl propanedioate
  参考文献：
  名称：

  Click chemistry with fullerene derivatives

  摘要：

  C(60) derivatives bearing either terminal alkyne or azide functional groups have been prepared and used as building blocks under the copper-mediated Huisgen 1,3-dipolar cycloaddition conditions leading to 1,2,3-triazole derivatives. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.04.064

文献信息

• Synthesis of fullerene building blocks bearing alkyne or azide groups and their subsequent functionalization by the copper mediated Huisgen 1,3-dipolar cycloaddition
  作者：Rossimiriam Pereira de Freitas、Julien Iehl、Béatrice Delavaux-Nicot、Jean-François Nierengarten

  DOI：10.1016/j.tet.2008.09.047

  日期：2008.12

  C-60 derivatives bearing either terminal alkyne or azide functional groups have been prepared and used as building blocks under the copper mediated Huisgen 1,3-dipolar cycloaddition conditions. In general, the reactivity of C60 toward azides does not significantly compete with the cycloaddition leading to the desired 1,2,3-triazole derivatives and good yields can be obtained when fullerene derivatives with reasonable Solubility are used as starting materials. The electrochemical properties of the new fullerene derivatives have also been investigated by cyclic voltammetry (CV) and Osteryoung Square Wave Voltammetry (OSWV). (C) 2008 Elsevier Ltd. All rights reserved.
• Click chemistry with fullerene derivatives
  作者：Julien Iehl、Rossimiriam Pereira de Freitas、Jean-François Nierengarten

  DOI：10.1016/j.tetlet.2008.04.064

  日期：2008.6

  C(60) derivatives bearing either terminal alkyne or azide functional groups have been prepared and used as building blocks under the copper-mediated Huisgen 1,3-dipolar cycloaddition conditions leading to 1,2,3-triazole derivatives. (C) 2008 Elsevier Ltd. All rights reserved.