1-tetradecanesulfonamide | 149220-45-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 1-tetradecanesulfonamide
• 英文别名: 1-Tetradecylsulfonamide；tetradecane-1-sulfonamide
• CAS: 149220-45-1
• 化学式: C₁₄H₃₁NO₂S
• 分子量: 277.472
• InChiKey: LUOPDTDAPPLUNE-UHFFFAOYSA-N

物化性质

• 沸点：
  393.5±25.0 °C(predicted)
• 密度：
  0.975±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  18
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  68.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-tetradecanesulfonamide 、 2,6-二异丙基苯异氰酸酯 在 盐酸 、 NaH 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 N-[2,6-bis(1-methylethyl)phenyl]-N'-(tetradecylsulfonyl)urea
  参考文献：
  名称：

  Sulfonyl urea and carbamate ACAT inhibitors

  摘要：

  一种降低血液胆固醇水平的药用化合物，其化学式为##STR1##其中X为氧或--NH--; Ar为苯基，取代苯基，萘基或取代萘基; R.sub.1为氢，低烷基或苄基; R.sub.2为直链或支链烷基，具有从5到17个碳原子，可以在1-碳位置上用甲基，乙基，苯基或取代苯基或有3到8个碳原子的环烷基取代。

  公开号：

  US05254589A1

文献信息

• [EN] TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF<br/>[FR] COMPOSÉS MODULATEURS DE TLR2, COMPOSITIONS PHARMACEUTIQUES ET LEURS UTILISATIONS
  申请人：AXIAL THERAPEUTICS INC

  公开号：WO2021242923A1

  公开（公告）日：2021-12-02

  The present disclosure relates to compounds which modulate the activity of Toll-like receptor (TLR) proteins, including agonists or activators, partial agonists, and antagonists. Of particular interest of compounds that modulate the activity of TLR2, as well as methods of using such compounds to treat cancer and other disorders associated with a TLR2 pathway.

  本公开涉及调节Toll样受体（TLR）蛋白活性的化合物，包括激动剂或激活剂、部分激动剂和拮抗剂。特别感兴趣的是调节TLR2活性的化合物，以及使用这些化合物治疗与TLR2通路相关的癌症和其他疾病的方法。
• MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE
  申请人：JNC Corporation

  公开号：US20150097162A1

  公开（公告）日：2015-04-09

  Provided is an organic electroluminescent element which has improved driving voltage and improved current efficiency. An organic electroluminescent element having the above-mentioned improved characteristics is provided by using, as a material for organic electroluminescent elements, a polycyclic aromatic compound in which a nitrogen atom and another heteroatom or a metal atom (X) are adjacent to each other in a non-aromatic ring.

  提供一种具有改进驱动电压和改进电流效率的有机电致发光元件。通过使用多环芳香化合物作为有机电致发光元件的材料，其中一个氮原子和另一个杂原子或金属原子（X）相邻于非芳香环中，提供了具有上述改进特性的有机电致发光元件。
• Color photographic light-sensitive material
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0133503A2

  公开（公告）日：1985-02-27

  A silver halide color photographic light-sensitive material is described, comprising a support having coated thereon at least one silver halide emulsion layer, the color photographic light-sensitive material having a photographic layer containing at least one kind of magenta coupler of 5-pyrazolone type having an arylthio group at the coupling position thereof, the arylthio group having an alkoxy group or an aryloxy group at the ortho position to the sulfur atom thereof and the alkoxy group and the aryloxy group being substituted with a cyano group, a halogen atom, a sulfonyl group, a sulfinyl group, a phosphonyl group, or an group, wherein A represents a chemical bond, an alkylene group, an arylene group, an oxygen atom, a sulfur atom, or an imino group; and B represents a hydroxy group, an alkoxy group, an aryloxy group, a hydrogen atom, an alkyl group, an aryl group, a heterocyclic group, an acyclic amino group, or a hydrazino group. The silver halide color photographic light-sensitive material containing the 2-equivalent magenta coupler has an excellent color forming property even when it is processed in a color developing solution containing a salt of alkaline earth metal, exhibits photographic properties which are not influenced by variations in the pH of the color developing solution, and provides a magenta color image having a good light fastness. A method of forming a color image using the silver halide color photographic light-sensitive material is also described.

  本发明描述了一种卤化银彩色感光材料，它包括一个支撑体，支撑体上涂覆有至少一层卤化银乳剂层，该彩色感光材料具有一个感光层，该感光层含有至少一种 5-吡唑酮型洋红色偶联剂，该偶联剂在其偶联位置上具有一个芳硫基、该芳硫基在其硫原子的正交位置上具有烷氧基或芳氧基，且该烷氧基和芳氧基被氰基、卤素原子、磺酰基、亚砜基、膦酰基或一个基团取代。 其中 A 代表化学键、亚烷基、亚芳基、氧原子、硫原子或亚氨基；B 代表羟基、烷氧基、芳氧基、氢原子、烷基、芳基、杂环基、无环氨基或肼基。 含有 2-当量品红色耦合剂的卤化银彩色感光材料即使在含有碱土金属盐的显色溶液中处理，也具有极佳的成色性能，其感光性能不受显色溶液 pH 值变化的影响，并能提供具有良好耐光性的品红色彩色图像。此外，还介绍了使用卤化银彩色感光材料形成彩色图像的方法。
• POLYARYLENE COPOLYMER AND USES THEREOF
  申请人：Sumitomo Chemical Company Limited

  公开号：EP2489690A1

  公开（公告）日：2012-08-22

  The present invention provides a polyarylene-based copolymer including a plurality of segments having an ion exchange group and a plurality of segments having substantially no ion exchange group, wherein at least one of the segments having an ion exchange group includes a polyarylene structure, the polystyrene-equivalent weight-average molecular weight of the segments having an ion exchange group is from 10,000 to 250,000, and the ion exchange capacity of the polyarylene-based copolymer is 3.0 meq/g or more.

  本发明提供了一种聚芳基烯基共聚物，包括多个具有离子交换基团的片段和多个基本上没有离子交换基团的片段，其中至少一个具有离子交换基团的片段包括聚芳基烯结构，具有离子交换基团的片段的聚苯乙烯当量平均分子量为 10,000 至 250,000 之间，聚芳基烯基共聚物的离子交换容量为 3.0 meq/g 或以上。
• POLYCYCLIC AROMATIC COMPOUND
  申请人：Kyoto University

  公开号：EP2752418B1

  公开（公告）日：2017-11-29