3-Decendicarbonsaeure | 128823-58-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3-Decendicarbonsaeure
• 英文别名: (E)-dec-3-enedioic acid
• CAS: 128823-58-5
• 化学式: C₁₀H₁₆O₄
• 分子量: 200.235
• InChiKey: YXFKNYQKLWPCJT-HWKANZROSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-Decendicarbonsaeure 在 sodium hydroxide 作用下， 生成 (E)-癸-2-烯二酸
  参考文献：
  名称：

  通过钯-膦配合物和二钴二羰基八丁烯催化的丁二烯的连续羰基化合成2-癸二酸（蜂王浆酸）

  摘要：

  钯配合物催化丁二烯在叔丁醇中的羰基化，得到3,8-壬二烯酸叔丁酯（I）。I在甲醇中用Co 2（CO）8进一步羰基化，得到-3-癸烯二酸叔丁酯（II）作为主要产物。II的水解和碱催化的异构化产生了E -2-癸二酸。

  DOI：

  10.1016/s0022-328x(00)91365-2
• 作为产物：
  描述：

  t-Butyl-3,8-nonadienoate 在 dicobalt octacarbonyl 吡啶 、 sodium hydroxide 作用下， 以 乙醇 为溶剂， 生成 3-Decendicarbonsaeure
  参考文献：
  名称：

  通过钯-膦配合物和二钴二羰基八丁烯催化的丁二烯的连续羰基化合成2-癸二酸（蜂王浆酸）

  摘要：

  钯配合物催化丁二烯在叔丁醇中的羰基化，得到3,8-壬二烯酸叔丁酯（I）。I在甲醇中用Co 2（CO）8进一步羰基化，得到-3-癸烯二酸叔丁酯（II）作为主要产物。II的水解和碱催化的异构化产生了E -2-癸二酸。

  DOI：

  10.1016/s0022-328x(00)91365-2

文献信息

• [EN] METHOD FOR THE SYNTHESIS OF ALKANE-1-HYDROXY-1,1-DIPHOSPHONIC ACID<br/>[FR] PROCÉDÉ DE SYNTHÈSE DE L'ACIDE ALCANE-1-HYDROXY-1,1-DIPHOSPHONIQUE
  申请人：STRAITMARK HOLDING AG

  公开号：WO2015059287A1

  公开（公告）日：2015-04-30

  The present invention is related to a new method for the synthesis of alkane-1-hydroxy-,1-diphosphonic acid or its salts which includes the steps of -reacting tetraphosphorus hexaoxide and a carboxylic acid under controlled reaction conditions; -hydrolyzing the formed alkane-1-hydroxy-1,1-diphosphonic acid condensates to form alkane-1-hydroxy-1,1-diphosphonic acid; -precipitating the alkane-1-hydroxy-1,1-diphosphonic acid through the use of a suitable solvent; -filtering the alkane-1-hydroxy-1,1-diphosphonic acid and recovering the mother liquor and the suitable solvent.1 The process according to the method of the present invention is highly controllable and is further characterized by a high selectivity.

  本发明涉及一种合成烷基-1-羟基-1,1-二膦酸或其盐的新方法，包括以下步骤：-在控制的反应条件下，将四磷六氧化物和羧酸反应；-水解形成的烷基-1-羟基-1,1-二膦酸缩聚物以形成烷基-1-羟基-1,1-二膦酸；-通过使用适当的溶剂沉淀烷基-1-羟基-1,1-二膦酸；-过滤烷基-1-羟基-1,1-二膦酸并回收母液和适当的溶剂。根据本发明的方法，该过程具有高度可控性，并且具有高选择性。
• Biological methods for modifying cellular carbon flux
  申请人：Radici Chimica S.p.A.

  公开号：US11174488B2

  公开（公告）日：2021-11-16

  The technology relates in part to biological methods for modifying carbon flux in cells, engineered cells and organisms in which cellular carbon flux has been modified, and methods of using engineered cells and organisms for production of organic molecules.

  该技术部分涉及改变细胞中碳通量的生物方法、改变细胞中碳通量的工程细胞和生物体，以及使用工程细胞和生物体生产有机分子的方法。
• METHOD FOR THE SYNTHESIS OF ALKANE-1-HYDROXY-1,1-DIPHOSPHONIC ACID
  申请人：Straitmark Holding AG

  公开号：EP3060567A1

  公开（公告）日：2016-08-31
• Method of analyzing dicarboxylic acids
  申请人：——

  公开号：US20020019056A1

  公开（公告）日：2002-02-14

  A novel method for the qualitative and quantitative analysis of dicarboxylic acids in biological samples is provided. The method includes the steps of estering the acid component of the sample and subsequently analyzing the esterified sample using tandem mass spectroscopy using atmospheric pressure ionization techniques in the positive ion mode. The method is particularly useful in the determination of methylmalonic acid in biological samples, and thus, the diagnosis of vitamin B 12 deficiency.
• Method For The Synthesis Of Alkane-1-Hydroxy-1,1-Diphosphonic Acid
  申请人：STRAITMARK HOLDING AG

  公开号：US20160251385A1

  公开（公告）日：2016-09-01

  The present invention is related to a new method for the synthesis of alkane-1-hydroxy-,1-diphosphonic acid or its salts which includes the steps of —reacting tetraphosphorus hexaoxide and a carboxylic acid under controlled reaction conditions; —hydrolyzing the formed alkane-1-hydroxy-1,1-diphosphonic acid condensates to form alkane-1-hydroxy-1,1-diphosphonic acid; —precipitating the alkane-1-hydroxy-1,1-diphosphonic acid through the use of a suitable solvent; —filtering the alkane-1-hydroxy-1,1-diphosphonic acid and recovering the mother liquor and the suitable solvent.1 The process according to the method of the present invention is highly controllable and is further characterized by a high selectivity.