N-2,3-dihydroxypropylacrylamide | 42521-68-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-2,3-dihydroxypropylacrylamide
• 英文别名: 1-Acrylamidopropan-2,3-diol；N-(2,3-dihydroxypropyl)prop-2-enamide
• CAS: 42521-68-6
• 化学式: C₆H₁₁NO₃
• 分子量: 145.158
• InChiKey: GFHMKLBDCUNICS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  69.6
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-氨基-1,2-丙二醇 、 丙烯酰氯 生成 N-2,3-dihydroxypropylacrylamide
  参考文献：
  名称：

  Paprotny,J. et al., Roczniki Chemii, 1976, vol. 50, p. 333 - 335

  摘要：

  DOI：

文献信息

• NON-AMPHIPHILE-BASED WATER-IN-WATER EMULSION AND USES THEREOF
  申请人：LUK Yan-Yeung

  公开号：US20090269323A1

  公开（公告）日：2009-10-29

  The present invention relates to a non-amphiphile-based water-in-water emulsion composition. The non-amphiphile-based water-in-water emulsion composition includes a water-soluble polymer, a non-amphiphilic lyotropic mesogen encapsulated by the water-soluble polymer; and water. In one embodiment, the non-amphiphilic lyotropic mesogen includes, without limitation, a lyotropic chromonic liquid crystal, and more specifically disodium cromoglycate (DSCG). In another embodiment, the water-soluble polymer can include, without limitation, a polyacrylamide, a polyol, a polyvinylpyrrolidone, a polysaccharide, or a water-soluble fluoride-bearing polymer. The present invention also relates to a porous hydrogel made with the use of the non-amphiphile-based water-in-water emulsion. The present invention further relates to using the emulsion and hydrogel for various applications.

  本发明涉及一种非两亲性基材的水包水乳液组合物。该非两亲性基材的水包水乳液组合物包括水溶性聚合物、被水溶性聚合物封装的非两亲性溶致液晶；和水。在一个实施例中，非两亲性溶致液晶包括但不限于溶致色浆液晶，更具体地是无钠 Cromoglicate (DSCG)。在另一个实施例中，水溶性聚合物可以包括但不限于聚丙烯酰胺、聚醇、聚乙烯吡咯烷酮、多糖或水溶性含氟聚合物。本发明还涉及一种用非两亲性基材的水包水乳液制成的多孔水凝胶。本发明进一步涉及使用该乳液和水凝胶用于各种应用。
• COSMETIC COMPOSITION COMPRISING AT LEAST ONE CATIONIC COPOLYMER AND AT LEAST ONE ANIONIC ASSOCIATIVE POLYMER AND COSMETIC TREATMENT PROCESSES USING SAID COMPOSITION
  申请人：BIGANSKA Olga

  公开号：US20090074692A1

  公开（公告）日：2009-03-19

  The disclosure relates to novel cosmetic compositions comprising, in a cosmetically acceptable medium: (i) at least one cationic polymer which are produced by polymerization of a mixture of monomers comprising: a) at least one vinyl monomer substituted with at least one amino group, b) at least one hydrophobic nonionic vinyl monomer, c) at least one associative vinyl monomer, and e) at least one hydroxylated nonionic vinyl monomer, and (ii) at least one anionic associative polymers.

  该披露涉及新型化妆品组合物，包括在适合用于化妆的介质中的：(i) 至少一种阳离子聚合物，其由包括：a) 至少一种含有至少一个氨基团的乙烯单体，b) 至少一种疏水非离子乙烯单体，c) 至少一种关联性乙烯单体，和e) 至少一种羟基化非离子乙烯单体的单体混合物聚合而成，以及(ii) 至少一种阴离子关联性聚合物。
• COSMETIC COMPOSITION COMPRISING A CATIONIC COPOLYMER AND A STARCH AND COSMETIC TREATMENT PROCESS THEREOF
  申请人：BIGANSKA Olga

  公开号：US20090074696A1

  公开（公告）日：2009-03-19

  The disclosure relates to novel cosmetic compositions comprising, in a cosmetically acceptable medium: (i) at least one cationic polymer which is obtained by polymerization of a mixture of monomers comprising: a) at least one vinyl monomer substituted with at least one amino group, b) at least one hydrophobic nonionic vinyl monomer, chosen from those of formulae (I) and (II): CH 2 ═C(X)Z,  (I) CH 2 ═CH—OC(O)R;  (II) wherein X, Z, and R are defined in the present specification; c) at least one associative vinyl monomer, and d) at least one hydroxylated nonionic vinyl monomer; and (ii) at least one starch. These compositions may have a texture which does not change over time and which may allow a better distribution, better lathering properties and also better cosmetic properties.

  该披露涉及一种新型化妆品组合物，包括在化妆品可接受的介质中：(i) 至少一种通过聚合包含以下单体混合物获得的阳离子聚合物：a) 至少一种含有至少一个氨基团的乙烯单体，b) 至少一种疏水非离子乙烯单体，选择自以下式(I)和(II)的那些：CH2═C(X)Z，(I)CH2═CH—OC(O)R；(II)，其中X、Z和R在本说明书中有定义；c) 至少一种缔合性乙烯单体，和d) 至少一种羟基化非离子乙烯单体；以及(ii) 至少一种淀粉。这些组合物可能具有随时间不变的质地，可能允许更好的分布、更好的起泡性能和更好的化妆性能。
• Universal supports for oligonucleotide synthesis
  申请人：Glen Research Corporation

  公开号：US20020137855A1

  公开（公告）日：2002-09-26

  Universal supports for oligonucleotide synthesis include a support material represented by the following formula: 1 In this formula, substituent A is selected from H, alkyl, aryl, or a polymeric or silica base material; substituent B is selected from acyl, aroyl, or a polymeric or silica base material; and substituent C is selected from a dimethoxytrityl group or a protecting group removable under acidic or neutral conditions. For the supports, one of substituents A or B constitutes the polymeric or silica base material. In use, an oligonucleotide is attached to the support at substituent C.

  通用寡核苷酸合成支持材料的公式如下所示：1在该公式中，取代基A选自H、烷基、芳基或聚合物或硅基材料；取代基B选自酰基、芳酰基或聚合物或硅基材料；取代基C选自二甲氧基三苯甲基基团或在酸性或中性条件下可去除的保护基团。对于这些支持材料，取代基A或B之一构成聚合物或硅基材料。在使用中，寡核苷酸被连接到取代基C上。
• X-ray contrast media for prolonged opacification
  申请人：Sovak, Milos

  公开号：EP0436316A1

  公开（公告）日：1991-07-10

  Hydroxyalkyl amino-substituted triiodobenzoates are provided, where the remaining position is substituted by amino or carboxy. The compounds have low solubility in the gastrointestinal tract, but are resorbable from extravisceral body cavities. They can be readily formulated and used as contract media for the plain radiography of the GI tract. Also, addition polymers comprised of triiodo compounds bonded through an amino nitrogen to a non-oxo-carbonyl group of an addition polymerizable monomer are provided. The polymers are highly water soluble physiologically acceptable, and not resorbable from the GI tract, but from the extravisceral body cavities. The polymers find use for computer tomography of the GI tract.

  提供了羟基烷基氨基取代三碘苯甲酸酯，其中剩余的位置被氨基或羧基取代。这些化合物在胃肠道中的溶解度较低，但可以从体腔外吸收。它们可以轻松地配制并用作胃肠道平片的对比介质。此外，提供了由三碘化合物通过氨基氮与可加聚单体的非氧羰基团结合而成的加聚物。这些聚合物在生理上高度水溶性，可接受，但不能从胃肠道吸收，而是从体腔外吸收。这些聚合物可用于胃肠道的计算机断层扫描。