pyrene-butanol | 63397-91-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 英文名称: pyrene-butanol
• 英文别名: 4-(pyren-2-yl)butan-1-ol；2-Pyrenebutanol；4-pyren-2-ylbutan-1-ol
• CAS: 63397-91-1
• 化学式: C₂₀H₁₈O
• 分子量: 274.362
• InChiKey: XZNIUURTXULQGK-UHFFFAOYSA-N

物化性质

• 沸点：
  488.4±24.0 °C(Predicted)
• 密度：
  1.217±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  pyrene-butanol 在 N-溴代丁二酰亚胺(NBS) 、 三苯基膦 作用下， 以 二氯甲烷 为溶剂， 以74%的产率得到2-(4-bromobut-1-yl)pyrene
  参考文献：
  名称：

  2'-固定脂锚核苷的合成及其在磷脂膜中的行为

  摘要：

  已经合成了各种在 2' 位带有一个或两个亲脂基团的新核苷。亲脂性取代基连接到 2'-羟基、2'-氨基或 2'-硫代官能团。这些亲脂性核苷锚定在用作磷脂膜模型的大型单层 POPC 囊泡中。通过核磁共振技术研究了这些分子插入到膜中的情况。为了进行比较，还研究了在 2'-、3'-或 5'-位置具有两个或三个亲脂基团的核苷。（© Wiley-VCH Verlag GmbH & Co. KGaA，69451 Weinheim，德国，2008 年）

  DOI：

  10.1002/ejoc.200701064
• 作为产物：
  描述：

  pyrenebutyric acid 在 dimethyl sulfide borane 作用下， 以 四氢呋喃 为溶剂， 反应 24.0h， 生成 pyrene-butanol
  参考文献：
  名称：

  一种结合芘和三苯基鏻盐的新型线粒体探针，用于通过荧光寿命测量进行细胞氧和自由基检测

  摘要：

  摘要 为了改善和多样化单细胞线粒体中活性氧 (ROS) 的量化，我们将芘衍生物 (PB) 连接到三苯基鏻盐 (TPP + ) 作为线粒体载体，形成 PB-TPP +探针。两个芘异构体与n合成并表征了连接在其 1-或 2-位上的-丁基三苯基鏻部分。利用芘的长荧光寿命，可以监测细胞自由基和氧的变化，并实时跟踪两种猝灭剂的可逆性。我们将这些新探针的行为与之前发表的芘探针进行了比较，芘探针由线粒体穿透肽功能化，允许它们转移到线粒体 (Mito-PB) 或芘丁酸 (PBA) 的细胞溶质膜。新探针的高细胞吸收允许细胞以比 Mito-PB 探针低 40 倍的初始浓度加载，而不会对细胞生长造成干扰。+基于探针的结果与基于 MPP 的探针的结果相当。然而，在负载浓度低至 25 nM 时，我们的技术允许在 TPP +载体存在的情况下检测线粒体中自由基产生的增加，这是对这个众所周知的载体用户的警告。

  DOI：

  10.1080/10715762.2022.2077202

文献信息

• Synthesis of Nucleosides with 2′-Fixed Lipid Anchors and Their Behavior in Phospholipid Membranes
  作者：Oliver Kaczmarek、Nicolai Brodersen、Andreas Bunge、Ludwig Löser、Daniel Huster、Andreas Herrmann、Anna Arbuzova、Jürgen Liebscher

  DOI：10.1002/ejoc.200701064

  日期：2008.4

  Various new nucleosides bearing one or two lipophilic groups at the 2′-position have been synthesized. The lipophilic substituents were attached to a 2′-hydroxy, 2′-amino, or 2′-thio function. These lipophilic nucleosides anchor in large unilamellar POPC vesicles serving as phospholipid membrane models. The insertion of these molecules into the membranes was investigated by NMR techniques. For comparison

  已经合成了各种在 2' 位带有一个或两个亲脂基团的新核苷。亲脂性取代基连接到 2'-羟基、2'-氨基或 2'-硫代官能团。这些亲脂性核苷锚定在用作磷脂膜模型的大型单层 POPC 囊泡中。通过核磁共振技术研究了这些分子插入到膜中的情况。为了进行比较，还研究了在 2'-、3'-或 5'-位置具有两个或三个亲脂基团的核苷。（© Wiley-VCH Verlag GmbH & Co. KGaA，69451 Weinheim，德国，2008 年）
• Can morphology tailoring based on functionalized fullerene nanostructures improve the performance of organic solar cells?
  作者：Lie Chen、Kai Yao、Yiwang Chen

  DOI：10.1039/c2jm33380e

  日期：——

  Nanowire, nanosheet and nanoflower supramolecular assemblies of fullerenes are constructed from self-organization of biphenyl and pyrene substituted PCBM. When 20 wt% PCBPy is blended into P3HT:PCBM as part of the acceptor, devices exhibit the best photovoltaic performance with PCE up to 4.8% by fine tuning of the morphology.

  富勒烯的纳米线、纳米片和纳米花超分子组合体是由联苯和芘取代的 PCBM 自组织构建而成的。当 20 wt% 的 PCBPy 掺入 P3HT:PCBM 作为受体的一部分时，通过微调形貌，器件表现出最佳的光伏性能，PCE 可高达 4.8%。
• COMB POLYMER
  申请人：COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

  公开号：US20210253760A1

  公开（公告）日：2021-08-19

  The present invention relates to a comb polymer comprising a main chain formed from 1-ethenyl- and/or 1-allyl-2,3,4,5,6-pentafluorobenzene monomers and polymeric side chains grafted in the para position of the pentafluorophenyl groups, in which said polymeric side chains are linked to said main chain by an oxygen atom, the molar grafting rate of polymeric side chains being greater than or equal to 50%. It also relates to a method for the preparation of such a comb polymer.
• SOLID POLYMER ELECTROLYTE BASED ON A COMB POLYMER
  申请人：COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

  公开号：US20210296699A1

  公开（公告）日：2021-09-23

  The present invention relates to a solid polymer electrolyte comprising: at least one comb polymer comprising a main chain formed from 1-ethenyl- and/or 1-allyl-2,3,4,5,6-pentafluorobenzene monomers, some of the monomer units of the main chain bearing polymeric side chains based on polymers that are solvents for alkali metal or alkaline-earth metal salts; said chains being grafted in the para position of the pentafluorophenyl groups; and at least one alkali metal or alkaline-earth metal salt, in particular a lithium salt. The invention also relates to a process for preparing a solid polymer electrolyte film and to the use thereof in an electrochemical system, in particular a lithium battery.
• PROCESS FOR PREPARING A SOLID ELECTROLYTE BASED ON POLYCARBONATES AND A COMPOSITE ELECTRODE COMPRISING SUCH A SOLID ELECTROLYTE
  申请人：COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

  公开号：US20220416298A1

  公开（公告）日：2022-12-29

  A process for preparing a solid electrolyte or a composite electrode incorporating a solid electrolyte, configured for an electrochemical system, may involve: (i) synthesizing, in a solvent medium, at least one (co)polymer by ring-opening (co)polymerization (ROP) of at least one 5-8-membered cyclic carbonate and, optionally, of at least one 5-8-membered lactone, catalyzed by Brønsted superacid(s) and initiated by compound(s) comprising hydroxide group(s); (ii) adding to the reaction medium a sufficient amount of an alkali metal or alkaline earth metal hydride, e.g., LiH, to neutralize all the catalyst and obtain an alkali metal or alkaline earth metal salt and to protect the terminal hydroxyl group(s) of the (co)polymer(s); (iii) optionally adding to the mixture from (ii) salt(s) of the alkali metal or alkaline earth metal, e.g., a lithium salt; and (iv) forming a solid electrolyte by evaporation of the solvent medium or a composite electrode incorporating the solid electrolyte.