methyl (E)-2-methyl-3-(tetrahydrofuran-2-yl)acrylate | 1433724-73-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: methyl (E)-2-methyl-3-(tetrahydrofuran-2-yl)acrylate
• 英文别名: methyl (E)-2-methyl-3-[(3R)-oxolan-3-yl]prop-2-enoate
• CAS: 1433724-73-2
• 化学式: C₉H₁₄O₃
• 分子量: 170.208
• InChiKey: KLRPADDRXASYDV-WVXIBAHESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2,5-二氢呋喃 、 甲基丙烯酸甲酯 在 Ru(naphthalene)(2-methylbicyclo[3.3.1]nona-2,6-diene) 作用下， 以 neat (no solvent) 为溶剂， 反应 168.0h， 以80%的产率得到
  参考文献：
  名称：

  Asymmetric Cross-Dimerization between Methyl Methacrylate and Substituted Alkene by Ru(0)–Bicyclononadiene Complex

  摘要：

  New Ru(0)-naphthalene complexes containing a bicyclononadiene ligand catalyze the linear cross-dimerization between methyl methacrylate and substituted alkenes by an oxidative coupling mechanism. The chiral (S,S)-2-methylbicyclo[3.3.1]nona-2,6-diene complex (S,5)-1b catalyzes asymmetric linear cross-dimerization between methyl methacrylate and 2,5-dihydrofuran to give the cross-dimer In 74% yield In 80% ee.

  DOI：

  10.1021/ol400963d

文献信息

• Asymmetric Cross-Dimerization between Methyl Methacrylate and Substituted Alkene by Ru(0)–Bicyclononadiene Complex
  作者：Yuki Hiroi、Nobuyuki Komine、Sanshiro Komiya、Masafumi Hirano

  DOI：10.1021/ol400963d

  日期：2013.5.17

  New Ru(0)-naphthalene complexes containing a bicyclononadiene ligand catalyze the linear cross-dimerization between methyl methacrylate and substituted alkenes by an oxidative coupling mechanism. The chiral (S,S)-2-methylbicyclo[3.3.1]nona-2,6-diene complex (S,5)-1b catalyzes asymmetric linear cross-dimerization between methyl methacrylate and 2,5-dihydrofuran to give the cross-dimer In 74% yield In 80% ee.