2-氰基-2-丁基苯并二硫酯 | 220182-83-2

• 物质功能分类: 医药中间体
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-氰基-2-丁基苯并二硫酯
• 英文名称: 1-cyano-1-methylpropyl dithiobenzoate
• 英文别名: 2-cyano-2-butyl dithiobenzoate；2-cyanobut-2-yl dithiobenzoate；2-Cyanobutan-2-yl benzenecarbodithioate
• CAS: 220182-83-2
• 化学式: C₁₂H₁₃NS₂
• 分子量: 235.374
• InChiKey: PLCFUVHOKGMNCT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  81.2
• 氢给体数：
  0
• 氢受体数：
  3

SDS

2-氰基-2-丁基苯二硫代酯MSDS英文版

反应信息

• 作为产物：
  描述：

  苯二硫代甲酸 、 2,2-Azodi(2-Methylbutyronitrile) 在 二甲基亚砜 作用下， 以 乙酸乙酯 为溶剂， 反应 16.0h， 生成 2-氰基-2-丁基苯并二硫酯
  参考文献：
  名称：

  Monodisperse, Micron-Sized Reactive Low Molar Mass Polymer Microspheres by Two-Stage Living Radical Dispersion Polymerization of Styrene

  摘要：

  Living/controlled radical dispersion polymerization of styrene was carried out in ethanol and in ethanol-water mixtures in the presence of perfluorohexyl iodide (C6F13I, 2-5 wt % based on styrene) as a degenerative chain transfer (DCT) agent or 1-cyano-1-methylpropyl dithiobenzoate (CMPDB, 0.5 and 1.0 mol % based on styrene) as a reversible addition-fragmentation chain transfer (RAFT) agent. These reagents disrupt the nucleation stage of particle formation when present at the start of the reaction. If their addition is delayed until the nucleation stage is complete, the reaction acquires the characteristics of a living/controlled radical polymerization: M-n increases linearly with the monomer conversion, and the molar mass distribution is much narrower (minimal M-w/M-n: 1.2) than polystyrene prepared without C6F13I or CMPDB. For reactions in ethanol, at low molar mass, the particles formed have a broad size distribution as a consequence of the solubility of the polymer at the reaction temperature, followed by precipitation upon cooling. When the reactions were run in a more polar medium (95 wt % aqueous ethanol), the polymer molecules precipitated as they were formed and were absorbed by the existing particles in the solution. The particles formed had an average diameter in the range 1-3 Am with a very narrow size distribution (CV < 1%). The polymer chains in these particles are reactive and chain-extendible.

  DOI：

  10.1021/ma061321j

文献信息

• [EN] COMPOSITIONS AND METHODS OF MANUFACTURING STAR POLYMERS FOR LIGAND DISPLAY AND/OR DRUG DELIVERY<br/>[FR] COMPOSITIONS ET PROCÉDÉS DE FABRICATION DE POLYMÈRES EN ÉTOILE POUR L'AFFICHAGE DE LIGAND ET/OU L'ADMINISTRATION DE MÉDICAMENT
  申请人：AVIDEA TECH INC

  公开号：WO2020214858A1

  公开（公告）日：2020-10-22

  A star polymer of formula O[P1]-([X]-A[P2]-[Z]-[P3])n where O is a core; A is a polymer arm attached to the core; X is a linker molecule between the core and the polymer arm; Z is a linker molecule between the end of the polymer arm and P3; P1, P2 and P3 are each independently one or more pharmaceutically active compounds that act extracellularly or intracellularly, n is an integer number; [ ] denotes that the group is optional; and at least one of P1, P2 or P3 is present.

  一个星形聚合物的化学式为O[P1]-([X]-A[P2]-[Z]-[P3])n，其中O是一个核心；A是连接到核心的聚合物臂；X是核心和聚合物臂之间的连接分子；Z是连接到聚合物臂末端和P3之间的连接分子；P1、P2和P3分别是一个或多个药物活性化合物，可以在细胞外或细胞内起作用，n是一个整数；[ ]表示该组是可选的；并且至少有一个P1、P2或P3存在。
• [EN] STAR POLYMER DRUG CONJUGATES<br/>[FR] CONJUGUÉS POLYMÈRE EN ÉTOILE-MÉDICAMENT
  申请人：AVIDEA TECH INC

  公开号：WO2022086853A1

  公开（公告）日：2022-04-28

  A star polymer of formula O[D1]-([X]-A(D2)-[Z]-[D3])n where O is a core; A is a polymer arm that comprises reactive monomers, hydrophilic monomers and/or charged monomers and is attached to the core; X is a linker molecule between the core and the polymer arm; Z is a linker molecule between the end of the polymer arm and D3; D1 is a drug molecule linked to the core; D2 is a drug molecule linked to reactive monomers distributed along the polymer arm; D3 is a drug molecule linked to the ends of the polymer arms; n is an integer number; [ ] denotes that the group is optional; and D2 is linked to the reactive monomers distributed along the polymer arm at a density of between 1 mol% and 80 mol%.

  一种星形聚合物，化学式为O[D1]-([X]-A(D2)-[Z]-[D3])n，其中O为核心；A为聚合物臂，包括反应性单体、亲水性单体和/或带电单体，并连接到核心；X为连接核心和聚合物臂的连接分子；Z为连接聚合物臂末端和D3的连接分子；D1为连接到核心的药物分子；D2为连接到沿着聚合物臂分布的反应性单体的药物分子；D3为连接到聚合物臂末端的药物分子；n为整数；[ ]表示该组是可选的；D2与沿聚合物臂分布的反应性单体以1 mol%至80 mol%的密度连接。
• SOLDER MASK INKJET INKS FOR MANUFACTURING PRINTED CIRCUIT BOARDS
  申请人：AGFA-GEVAERT

  公开号：EP3321332A1

  公开（公告）日：2018-05-16

  The invention provides an inkjet method for producing a solder mask in the manufacture of a Printed Circuit Board. By using a solder mask inkjet ink containing at least one photo-initiator, at least one free radical polymerizable compound and at least one RAFT compound as adhesion promoter, a high quality solder mask withstanding the high thermal stress during the soldering process while maintaining excellent physical properties, may be produced.

  本发明提供了一种在印刷电路板制造过程中生产焊接掩模的喷墨方法。通过使用含有至少一种光引发剂、至少一种自由基可聚合化合物和至少一种作为附着力促进剂的 RAFT 化合物的焊接掩模喷墨墨水，可以生产出高质量的焊接掩模，既能承受焊接过程中的高热应力，又能保持良好的物理性能。
• Solder mask inkjet inks for manufacturing printed circuit boards
  申请人：AGFA-GEVAERT NV

  公开号：US11091659B2

  公开（公告）日：2021-08-17

  An inkjet method for producing a solder mask in the manufacture of a Printed Circuit Board uses a solder mask inkjet ink containing at least one photo-initiator, at least one free radical polymerizable compound and at least one RAFT compound as adhesion promoter. A high quality solder mask withstanding the high thermal stress during the soldering process while maintaining excellent physical properties is produced.

  一种用于制造印刷电路板的焊接掩模的喷墨方法使用一种焊接掩模喷墨墨水，该墨水含有至少一种光引发剂、至少一种可自由基聚合的化合物和至少一种作为附着力促进剂的 RAFT 化合物。生产出的高质量阻焊层既能承受焊接过程中的高热应力，又能保持良好的物理特性。
• SYNTHESIS OF DITHIOESTER CHAIN TRANSFER AGENTS
  申请人：Commonwealth Scientific and Industrial Research Organisation

  公开号：EP1149075B1

  公开（公告）日：2008-12-31