4-amino-2-butyl-pyrimidine-5-carbonitrile | 90562-77-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 4-amino-2-butyl-pyrimidine-5-carbonitrile
• 英文别名: 4-Amino-2-butyl-pyrimidin-5-carbonitril；4-Amino-2-butylpyrimidine-5-carbonitrile；4-amino-2-butylpyrimidine-5-carbonitrile
• CAS: 90562-77-9
• 化学式: C₉H₁₂N₄
• 分子量: 176.221
• InChiKey: WUOLOMHZSCGVFM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  75.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-amino-2-butyl-pyrimidine-5-carbonitrile 在 盐酸 、 水 作用下， 生成 4-Amino-5-aminomethyl-2-butyl-pyrimidin
  参考文献：
  名称：

  Does Age Change the Distribution of Visual Attention? A Comment on McCalley, Bouwhuis, and Juola (1995)

  摘要：

  A paper, by McCalley, Bouwhuis, and Juola (1995) suggested differences between younger and older adults in the use of visual cues. Furthermore, they reported these differences could largely be attributed to diminished (peripheral al) visual proressing capacities of elderly adults. I-It re, we reanalyze the data of McCalley and colleagues emphasizing relative rather than absolute differences. We find that when doing so, the data do not reveal differences in the way older and younger adults transiently allocate attention during visual search. Contrary to the conclusions of McCalley and colleagues, the similarity between the younger and older observers is therefore independent of the characteristics of the visual information. Furthermore, in our view the data suggest that older adults have foveal rather than peripheral visual processing difficulties. The results reemphasize the importance of the analytical approach taken in aging research, We discuss the difficulties and relevance of controlling and separating visual and attentional factors in age-related studies.

  DOI：

  10.1093/geronb/55.3.p187
• 作为产物：
  描述：

  ethyl valerimidate 、 (氨基亚甲基)丙二腈 生成 4-amino-2-butyl-pyrimidine-5-carbonitrile
  参考文献：
  名称：

  Does Age Change the Distribution of Visual Attention? A Comment on McCalley, Bouwhuis, and Juola (1995)

  摘要：

  A paper, by McCalley, Bouwhuis, and Juola (1995) suggested differences between younger and older adults in the use of visual cues. Furthermore, they reported these differences could largely be attributed to diminished (peripheral al) visual proressing capacities of elderly adults. I-It re, we reanalyze the data of McCalley and colleagues emphasizing relative rather than absolute differences. We find that when doing so, the data do not reveal differences in the way older and younger adults transiently allocate attention during visual search. Contrary to the conclusions of McCalley and colleagues, the similarity between the younger and older observers is therefore independent of the characteristics of the visual information. Furthermore, in our view the data suggest that older adults have foveal rather than peripheral visual processing difficulties. The results reemphasize the importance of the analytical approach taken in aging research, We discuss the difficulties and relevance of controlling and separating visual and attentional factors in age-related studies.

  DOI：

  10.1093/geronb/55.3.p187

文献信息

• Does Age Change the Distribution of Visual Attention? A Comment on McCalley, Bouwhuis, and Juola (1995)
  作者：F. W. Cornelissen、A. C. Kooijman

  DOI：10.1093/geronb/55.3.p187

  日期：2000.5.1

  A paper, by McCalley, Bouwhuis, and Juola (1995) suggested differences between younger and older adults in the use of visual cues. Furthermore, they reported these differences could largely be attributed to diminished (peripheral al) visual proressing capacities of elderly adults. I-It re, we reanalyze the data of McCalley and colleagues emphasizing relative rather than absolute differences. We find that when doing so, the data do not reveal differences in the way older and younger adults transiently allocate attention during visual search. Contrary to the conclusions of McCalley and colleagues, the similarity between the younger and older observers is therefore independent of the characteristics of the visual information. Furthermore, in our view the data suggest that older adults have foveal rather than peripheral visual processing difficulties. The results reemphasize the importance of the analytical approach taken in aging research, We discuss the difficulties and relevance of controlling and separating visual and attentional factors in age-related studies.