methyl (2S)-2-(pent-4-enylamino)propanoate | 195310-87-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: methyl (2S)-2-(pent-4-enylamino)propanoate
• CAS: 195310-87-3
• 化学式: C₉H₁₇NO₂
• 分子量: 171.239
• InChiKey: YYVDVYXYTDLYGT-QMMMGPOBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  methyl (2S)-2-(pent-4-enylamino)propanoate 在 偶氮二异戊腈 、 三正丁基氢锡 、 三乙胺 作用下， 以 乙醚 、 甲苯 为溶剂， 反应 7.0h， 生成 (S)-2-(2-Methyl-pyrrolidin-1-yl)-propionic acid methyl ester
  参考文献：
  名称：

  Cyclisation of Aminyl Radicals Derived from Amino Acids

  摘要：

  alpha-Amino acid aminyl radicals have been generated from sulfenamide precursors using Bu3SnH. The aminyl radicals undergo 5-exo-trig cyclisation reactions onto suitably placed N-alkenyl or alpha-alkenyl chains on the amino acids with reasonable diastereoselectivity. The alpha-ester of the amino acid imparts electrophilic behaviour to the aminyl radicals and facilitates cyclisation onto alkenes. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)01413-5
• 作为产物：
  描述：

  methyl (2S)-2-[pent-4-enyl(phenylsulfanyl)amino]propanoate 在 偶氮二异戊腈 、 三正丁基氢锡 作用下， 以 甲苯 为溶剂， 反应 6.0h， 生成 methyl (2S)-2-(pent-4-enylamino)propanoate 、 (S)-2-(2-Methyl-pyrrolidin-1-yl)-propionic acid methyl ester
  参考文献：
  名称：

  Cyclisation of Aminyl Radicals Derived from Amino Acids

  摘要：

  alpha-Amino acid aminyl radicals have been generated from sulfenamide precursors using Bu3SnH. The aminyl radicals undergo 5-exo-trig cyclisation reactions onto suitably placed N-alkenyl or alpha-alkenyl chains on the amino acids with reasonable diastereoselectivity. The alpha-ester of the amino acid imparts electrophilic behaviour to the aminyl radicals and facilitates cyclisation onto alkenes. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)01413-5

文献信息

• MULTI-METALLIC ORGANOMETALLIC COMPLEXES, AND RELATED POLYMERS, COMPOSITIONS, METHODS AND SYSTEMS
  申请人：RADLAUER Madalyn

  公开号：US20130066029A1

  公开（公告）日：2013-03-14

  Multi-metallic organometallic complexes that allow performance of olefin based reaction and in particular polymerization of olefins to produce polyolefin polymers, and related methods and systems are described.

  描述了一种多金属有机金属配合物，可用于进行基于烯烃的反应，特别是进行烯烃的聚合以生产聚烯烃聚合物，以及相关的方法和系统。
• US9233996B2
  申请人：——

  公开号：US9233996B2

  公开（公告）日：2016-01-12
• [EN] MULTI-METALLIC ORGANOMETALLIC COMPLEXES, AND RELATED POLYMERS, COMPOSITIONS, METHODS AND SYSTEMS<br/>[FR] COMPLEXES ORGANOMÉTALLIQUES À PLUSIEURS MÉTAUX, ET POLYMÈRES, COMPOSITIONS, PROCÉDÉS ET SYSTÈMES CORRESPONDANTS
  申请人：CALIFORNIA INST OF TECHN

  公开号：WO2013040276A1

  公开（公告）日：2013-03-21

  Multi-metallic organometallic complexes that allow performance of olefin based reaction and in particular polymerization of olefins to produce polyolefin polymers, and related methods and systems are described.
• Cyclisation of Aminyl Radicals Derived from Amino Acids
  作者：W.Russell Bowman、Michael J Broadhurst、Daniel R Coghlan、Kirk A Lewis

  DOI：10.1016/s0040-4039(97)01413-5

  日期：1997.9

  alpha-Amino acid aminyl radicals have been generated from sulfenamide precursors using Bu3SnH. The aminyl radicals undergo 5-exo-trig cyclisation reactions onto suitably placed N-alkenyl or alpha-alkenyl chains on the amino acids with reasonable diastereoselectivity. The alpha-ester of the amino acid imparts electrophilic behaviour to the aminyl radicals and facilitates cyclisation onto alkenes. (C) 1997 Elsevier Science Ltd.