1,3,5-triformylhexahydro-1,3,5-triazine | 58793-59-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪烷类
• 英文名称: 1,3,5-triformylhexahydro-1,3,5-triazine
• 英文别名: 1,3,5-Triazinane-1,3,5-tricarbaldehyde
• CAS: 58793-59-2
• 化学式: C₆H₉N₃O₃
• 分子量: 171.156
• InChiKey: FJAFCPLWDGAVJN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  60.9
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  oxymethyl methyl carbonate 、 乌洛托品 以62%的产率得到
  参考文献：
  名称：

  AGADZHANYAN, TS. E.;ARUTYUNYAN, G. L.;MINASYAN, G. G.;MOVSESYAN, R. A., ARM. XIM. ZH., 1983, 36, N 10, 669-672

  摘要：

  DOI：

文献信息

• Phosphorous organic compounds and their use
  申请人：Jomaa Pharmaka GmbH

  公开号：US20030036533A1

  公开（公告）日：2003-02-20

  Use of phosphorous organic compounds of general formula (I) 1 wherein B represents either an ether group of the formula (II) 2 or a keto group of the formula (III) 3 is a 5 or 6 membered cyclic compound, and their use for preparing pharmaceutical compositions for the therapeutic and prophylactic treatment of infections in humans and animals due to viruses, bacteria, fungi, and parasites as well as their use as a fungicide, bactericide and herbicide in plants.

  通用公式（I）中磷有机化合物的用途 其中B代表公式（II）中的醚基 或者公式（III）中的酮基 是一种5或6元环化合物， 以及它们用于制备用于治疗和预防人类和动物感染病毒、细菌、真菌和寄生虫的药物组合物，以及它们在植物中作为杀真菌剂、杀菌剂和除草剂的用途。
• HOCHSELEKTIVE UND SENSITIVE DETEKTION VON 2,4,6-TRINITROTOLUOL MITTELS FLUORESZENZVERSTÄRKUNG DURCH UV INDUZIERTE PHOTOREAKTION MIT ANIONEN
  申请人：Bundesrepublik Deutschland, Vertreten Durch Die Bundesministerin für Wirtschaft und Energie, Diese vertreten durch den Präsidenten der

  公开号：EP3489663A1

  公开（公告）日：2019-05-29

  Verfahren zum Nachweis eines Analyten umfassend 2,4,6-Trinitrotoluol in einer Probe umfassend: Bereitstellen einer Indikatorlösung, umfassend ein Kation und ein Anion; in-Kontakt-Bringen und/oder Wechselwirken von Indikatorlösung und der den Analyten enthaltenden Probe; photokatalytisch induziertes Ausbilden eines anionischen TNT-Sigma-Komplexes umfassend den Analyten und das Anion durch Belichten der miteinander in Kontakt gebrachten Indikatorlösung und Probe; fluoreszenzoptisches Nachweisen des ausgebildeten anionischen TNT-Sigma-Komplexes.

  一种检测样品中包含 2,4,6-三硝基甲苯的分析物的方法，包括：提供包含阳离子和阴离子的指示剂溶液；使指示剂溶液和包含分析物的样品接触和/或相互作用；通过将接触的指示剂溶液和样品暴露于光，光催化诱导形成包含分析物和阴离子的阴离子 TNT-sigma 复合物；荧光-光学检测形成的阴离子 TNT-sigma 复合物。
• Highly selective and sensitive detection of 2,4,6-trinitrotoluene by means of fluorescence enhancement using UV-induced photoreaction with anions
  申请人：Bundesrepublik Deutschland, Vertreten Durch Den Bundesrepublik Für Wirtschaft Und Energie

  公开号：US10976256B2

  公开（公告）日：2021-04-13

  A method for detecting an analyte comprising 2,4,6-trinitrotoluene in a sample comprising: providing an indicator solution, comprising a cation and an anion; bringing in contact and/or interacting the indicator solution and the sample comprising the analyte; photocatalytically induced forming of an anionic TNT sigma complex, comprising the analyte and the anion, by means of exposure of the indicator solution and the sample brought in contact with one another; fluorescence optically detecting the formed anionic TNT sigma complex.

  一种检测样品中包含 2,4,6-三硝基甲苯的分析物的方法，包括：提供包含阳离子和阴离子的指示剂溶液；使指示剂溶液和包含分析物的样品接触和/或相互作用；通过指示剂溶液和相互接触的样品的曝光，光催化诱导形成包含分析物和阴离子的阴离子 TNT sigma 复合物；荧光光学检测形成的阴离子 TNT sigma 复合物。
• Structural studies on bioactive compounds. 4. A structure-antitumor activity study on analogs of N-methylformamide
  作者：E. Nicholas Gate、Michael D. Threadgill、Malcolm F. G. Stevens、David Chubb、Lisa M. Vickers、Simon P. Langdon、John A. Hickman、Andreas Gescher

  DOI：10.1021/jm00156a024

  日期：1986.6

  A series of derivatives of N-methylformamide (NMF), an experimental antitumor agent, has been prepared, having the general formula R3C(X)NR1R2 where R1 = H, CH3, CD3, CH2CF3, CH2CH2Cl, cyclopropyl, C2H5, CH2OH, CH2OR, CH2N(CH3)2; R2 = H, CH3; R3 = H, CF3, CCl3, CH3, Ph, NHCH3, N(CH3)2; and X = O, S, NH. A further short series of "push-pull" olefins of the general formula R1R2C = CHNR3R4 has been synthesized where R1 = H, CH3 and R2 = H, NO2, CN, CHO, CH3 and R3 = H and R4 = H, CH3, morpholino. These compounds have been tested for activity against the M5076 ovarian sarcoma and the TLX5 lymphoma in mice. NMF was by far the most potent agent of both series with activity against both tumors. Some other compounds showed weak activity, but there is a rigorous structural requirement for activity and most analogues were inactive. Certain members of the series exist as equilibrium mixtures of rotamers about the amide or pro-amide bonds as shown by NMR.
• Highly Selective and Sensitive Detection of 2,4,6-Trinitrotoluene by Means of Fluorescence Enhancement Using UV-Induced Photoreaction with Anions
  申请人：Bundesrepublik Deutschland, Vertreten Durch Den Bundesrepublik Für Wirtschaft Und Energie

  公开号：US20190154581A1

  公开（公告）日：2019-05-23

  A method for detecting an analyte comprising 2,4,6-trinitrotoluene in a sample comprising: providing an indicator solution, comprising a cation and an anion; bringing in contact and/or interacting the indicator solution and the sample comprising the analyte; photocatalytically induced forming of an anionic TNT sigma complex, comprising the analyte and the anion, by means of exposure of the indicator solution and the sample brought in contact with one another; fluorescence optically detecting the formed anionic TNT sigma complex.